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Biomedical subjects

B de Toffol

Publications and source records attributed to B de Toffol.

At least 73 records · Page 4Linked to original sources

Influence of lateralized neuropsychological activities with and without sensorimotor components on EEG spectral power (alpha-rhythm).

Spectral analysis of the EEG (alpha-rhythm) was studied in 8 young right-handed men who underwent 6 experimental tasks which were compared with rest, and included two pure motor activities using only the right and then the left hand, two pure neuropsychological tasks, and two "mixed" tasks with both neurophysiological and motor activities. The electrophysiological parameters studied were the log of spectral power and an asymmetry index (RP-LP)/(RP + LP). In order to demonstrate lateralization of the EEG, one must associate lateralized motor and neuropsychological tasks (which are supposed to preferentially involve one of the cerebral hemispheres). These results may reconcile apparently divergent views published in the literature with respect to lateralized EEG modifications associated with cognitive activities.

Adult↗

Multiple cerebral angiomas and Rendu-Osler-Weber disease: case report.

A 25-year-old man was hospitalized after suffering a subarachnoid hemorrhage. Arteriograms disclosed two arteriovenous malformations, one of which was asymptomatic. Rendu-Osler-Weber disease was suspected because of the concomitant existence of cutaneous telangiectases. Review of the literature shows that in 12 previously published cases involving multiple arteriovenous malformations, this diagnosis was established five times. The indications for surgical treatment are discussed.

Adult↗

Two mesencephalic lacunar infarcts presenting as Claude's syndrome and pure motor hemiparesis.

Two exceptional cases of mesencephalic lacunar infarcts located both in the anterior vascular territory are reported. In patient 1, the infarct selectively involved the red nucleus, thus resulting in a Claude's syndrome. In patient 2, the lesion was limited to the external 2/3 of the cerebral peduncle, and was responsible for a pure motor hemiplegia (PMH). CT scan easily demonstrated the lesion in both cases. Claude's syndrome is very unusual, and PMH has only been reported once before in a mesencephalic infarct. The reasons why these lesions are so uncommon are discussed.

Aged↗

Spectral analysis of the EEG (alpha rhythm) and activity in the left hemisphere: the effects of lateral gaze.

This study tests the effect of maintaining right and left lateral gaze during a writing task which preferentially implicates the left hemisphere using an asymmetry parameter calculated from the spectral power of the alpha rhythm (RP-LP/RP + LP) in a right-handed patient undergoing the same experimental regimen nine times. A six derivation EEG was recorded. Maintaining left lateral gaze (toward the active hemisphere) removes the lateralization found during writing while staring straight ahead whereas maintaining right lateral gaze (toward the side opposite the active hemisphere) results in slightly lower values which are however, not significantly different from those obtained during staring straight ahead. This study adds an electrophysiologic aspect to Kinsbournes's paradigm on gaze position and hemispheric activation.

Adult↗

Are frequent spike-waves during non-REM sleep in relation with an acquired neuro-psychological deficit in epileptic children?

In a population of 11 children with frequent spike waves during non REM sleep who had no neurological symptoms between birth and their first symptom, 3 groups were compared according to their neuropsychological performances. In the first group, the children had no intellectual deficit, in the second group, they had an acquired aphasia as in the Landau-Kleffner syndrome and in the third they had severe behavioural disorder and mental deterioration. The non REM sleep paroxysmic activity density tended to be highest in the third group, variable in the second group and moderate in the first group, and their topography was always generalized in the acute phase in groups II and III but asymmetrical in group I. The EEG anomalies disappeared during adolescence but in group II and III children a moderate to severe delay in school work persisted.

Aphasia↗

Hydrocephalus and cavernoma of the cauda equina.

The association of a tumor of the cauda equina and hydrocephalus is unusual. We report a case of hydrocephalus with normal pressure associated with an equally rare affliction, a cavernous angioma of the cauda equina, which regressed after surgical ablation. The physiological mechanism involved is discussed.

Aged↗

Progressive necrosis of the conus medullaris: magnetic resonance imaging and surgical findings.

A 67-year-old man with non-insulin-dependent diabetes mellitus progressively developed, over a 2-year period, lower extremity sensory and motor defects associated with impaired bladder function and perineal and perianal sensation related to a disease of the conus medullaris extending from T12 to S5. The magnetic resonance imaging scan suggested myelomalacia and the diagnosis of progressive necrotic myelopathy was confirmed by surgical intervention.

Aged↗

Chronic cervical radiation myelopathy diagnosed by MRI.

We report a case of chronic cervical myelopathy which developed after radiotherapy for differentiated carcinoma of the buccal cavity. The myelopathy was diagnosed by the finding of severe cervical cord atrophy at MRI.

Adult↗

A syndrome of REM and non-REM sleep reduction and lateral gaze paresis after medial tegmental pontine stroke. Computed tomographic scans and anatomical correlations in four patients.

A common pattern of reduction in both rapid eye movement and non-rapid eye movement sleep associated with various lateral gaze paralyses was present in four cases of brain-stem stroke. From computed tomographic scan data, clinical inferences, and, in two cases, neuropathologic sections, the common lesions were localized in the medial pontine tegmentum, ie, the inner part of the gigantocellular and pontis centralis caudalis nuclei. These data in humans were compared with lesions obtained experimentally in cats.

Adult↗

[EEG spectral analysis in sylvian ischemia with normal value tracings].

The EEG power spectral analysis of 8 patients with a definite sylvian ischemia, the standard EEG of which was normal, was determined in comparison with the date of a control group (N = 14). We calculated the right-left power spectral differences in 4 symmetrical bipolar leads for 5 rhythms (delta: 1.2-3.1 Hz, theta: 3.5-7 Hz, alpha: 7.4-12.3 Hz, beta 1: 12.9-14.1 Hz and beta 2: 15.2-17.2 Hz). For each patient, the spectral difference is measured in comparison with the normal range of the control group with an alpha risk of 5%. There are 54 asymmetries favouring the lesioned side (mostly in 5 patients) and 6 the opposite, without predominance of a particular rhythm with the exception of the beta 2 rhythm which presents no asymmetries.

Aged↗

[Biofeedback of blood pressure information in man: changes in the electroencephalographic power spectrum].

Modifications of attention in cardiovascular field with the aim of a perceptive activity focused on a vegetative feature may include in man: a specific arousal component linked to significant visual information (blood pressure); an unspecific attention component (P300), obvious in modifications of averaged visual response in the same time to a background unsignificant stimulation.

Biofeedback, Psychology↗