Biomedical subjects

B Zinnbauer

Publications and source records attributed to B Zinnbauer.

8 recordsLinked to original sources

PubMed1995

[Asynchronous bilateral hydronephrosis in retroperitoneal fibrosis with an interval of 44 months].

The case of a man, now aged 53 years, with bilateral, asynchronous (44 months apart) hydronephrosis caused by retroperitoneal fibrosis is reported. A review of the literature with reference to the reported side effects of H2-antagonists (which the patient had taken immediately before developing the hydronephrosis) does not reveal any definite relation between the disease and these drugs. Stenosis and medialization of the middle third of the ureter (mostly bilateral) should suggest retroperitoneal fibrosis to the urologist, as early surgical treatment is mandatory to preserve renal function. Postoperatively, immunosuppression for at least 6 months is highly recommended to prevent recurrence.

Cimetidine↗

PubMed1990

[Clinical efficacy and nephrotoxicity of gentamicin in single-dose parenteral administration of total individually adapted daily dosage].

The efficacy of gentamicin given intravenously once daily in a single, individually-adapted dose in form of a short infusion was confirmed in 30 patients with febrile urogenitary infections, taking nephrotoxicity into consideration. Antibiotic therapy was given for 7 days in each case, the individual dose of gentamicin being chosen from the dosage schedule according to Mawer. Depending on weight, age and renal function we used daily doses ranging from 160 to 480 mg (i.e. 2 to 5 mg/kg) of gentamicin. All patients were cured and all gram-negative bacteria were eliminated; no nephrotoxicity was recorded, as verified by constantly low serum levels of gentamicin (below the recommended peak level of 2 micrograms/ml) and non-significant changes in serum creatinine level. According to our results and to the findings of other investigations cited in the literature we conclude that in gentamicin therapy the once-daily individually--adapted intravenous dosage regimen is superior to to continuous administration by means of repeated daily doses with regard to efficacy and absence of nephrotoxicity.

Adult↗

PubMed1972