Biomedical subjects
Publications and source records attributed to B Z Silverstone.
A case of isolated arteriovenous communication of the retina (AVCR) decompensated to central retinal vein occlusion and visual loss resulted. This decompensation is not rare. Therefore, photocoagulation of the shunting vessels has to be the preferred treatment.
In ten cases of nontraumatic retinal tears with initial vitreous hemorrhages so dense that all retinal detail was obscured, medical management included hospitalization, sedation, and binocular patching. It took an average of 4.3 days for the vitreous to clear so that the tears could be examined. All the tears were on or anterior to the equator, and all were in the superior quadrants. Surgery was performed promptly once the tears were visible even though much of the retina was still covered with hemorrhage. After total clearing of the vitreous, no additional retinal tears were found in any of the ten cases. Postoperative complications included hemorrhages in three cases, macular pucker in one case, and a paramacular star in one case.
There is considerable evidence which supports a link between abnormalities in copper metabolism and some pigmentary retinopathies. In a previous study, we found such abnormalities in high myopic Caucasian patients. Since the incidence of myopia, and the connection of the latter with retinal detachment, in the black are different from those found in the Caucasian, we modeled the present study on the black after the above-mentioned one carried out on the Caucasian. In the present study no abnormalities in copper metabolism were present, in the black high myopic patient.
A family affected with pituitary dwarfism transmitted probably as an X-linked recessive or autosomal recessive condition, is described. The propositus had globular-like changes in his cornea, this latter as a sequela of endocrine disturbances, is suggested and discussed.
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We described a family in which two siblings were suffering from Alport's syndrome. Both had identical ocular lesions: whitish-grey dots in the superficial layers of the retina mainly in the posterior pole. The visual acuity, the visual field, and the fundus fluorescein angiogram were normal. These lesions were associated with an impaired ERG. The ocular finding seems to be characteristic of the Alport's syndrome.