PubMed1989
In this study, 30 cases of male smokers aged 35.7 +/- 5.2 years mean and 30 male nonsmokers aged 36.6 +/- 6.8 years were selected from a factory. Before the assay, everyone smoked one pack of cigarette in a day, after that these tests were done. The experimental results as follows. 1. Comparing with control group, the levels of IgG and IgM in serum of smoking group are lower. It was shown that smoking has an inhibitive effect on phagocytosis and bactericidal of AM, so smoking has a damaging and prohibitive effect on the immunity of the body. 2. Smoking increases the level of serum IgE. 3. The increase of the level of CIC in serum in smoking individuals suggested that the defensive function decreases and the infectious susceptibility increases. So we should pay greatest attention to the occurrence of allergic disease of type III. 4. Smoking increases the level of serum elastase. 5. The level of TXB2 in human plasma of smokers increases. The result suggested that smoke plays an important role in cardiovascular diseases. 6. The decrease of the level of cAMP in the plasma of smokers may be related to the release of some mediators. 7. The increase of the level of vWF in the plasma of smokers may suggest that there are lesions in the endothelium of pulmonary blood vessels.