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Biomedical subjects

B Weiner

Publications and source records attributed to B Weiner.

At least 73 records · Page 4Linked to original sources
PubMed1978

Rapid treatment of percodan addiction: a case report.

This is a case study of narcotic addiction in which the patient was completely withdrawn from 12 to 20 Percodan tablets daily within 7 days. Signs and symptoms of the Abstinence Syndrome were minor and required minimal medication for their control. In addition, no electroshock treatment was necessary, nor were any other narcotic or other drug substituted for the Percodan.

Adult↗
PubMed1978

Effects of attributions for success and failure on the performance of retarded adults.

Seventy-two TMR adults were given success and failure experiences at a coding task, as well as one of three causal attributions (ability, effort, or task difficulty [ease]). The data revealed that causal ascriptions interacted with outcome in influencing speed of performance and that success enhanced performance only when coupled with an ability ascription. The data suggested that some of the contradictions in the success-failure literature may be due to differential causal attributions elicited across the various investigations. The implications of these data for training programs also were discussed.

Achievement↗
PubMed1976

Stability of gentamicin sulfate injection following unit dose repackaging.

The potency of gentamicin sulfate following repackaging in disposable syringes were determined by a modification of the agar diffusion bioassay, using a highly gentamicin-resistant strain of Psuedomonas aeruginosa to assay milligram quantities of active drug. Three factors were studied at 30, 60 and 90 days: (1) syringe character (glass vs plastic); (2) temperature (25 C vs 4 C); and (3) volume of aspirated sample. Glass syringes were superior at all time intervals. Storage in plastic for even 30 days resulted in unacceptable loss of potency (greater than 15%) and formation of a brown precipitate. Mass spectrophotometry indicated that this precipitate consisted mainly of esters of phthalic acid (plasticizer) and methylparaben (gentamicin preservative). Temperature had no effect on retained potency. A positive correlation between the percent potency lost and volume of gentamicin aspirated was demonstrated in both glass and plastic.

Drug Packaging↗
PubMed1975

Occupational lead nephropathy.

Among eight subjects suspected of excessive occupational exposure to lead, detailed examination of renal function identified abnormalities in four. Glomerular filtration rate was less than 87 ml/mim/1.73 m2 in one subject with asymptomatic renal failure, and in three subjects with preclinical renal dysfunction. In the subject with asymptomatic renal failure, chelation therapy increased the glomerular filtration rate, p-aminohippurate (PAH) extraction, the maximal PAH secretion rate (TmPAH) and improved proximal tubule ultrastructure, despite decreased renal plasma flow. This improvement in PAH transport was associated with correction of a proximal tubule defect in tritiated PAH uptake detected by section freeze-dry autoradiography of renal biopsy specimens. In three subjects, the etiologic diagnosis of lead-induced nephropathy was established by exclusion, but tubular dysfunction did not obviously exceed the reduction in blomerular filtration. Proximal tubule abnormalities were seen in each of the three patients who underwent biopsy. These studies suggest that lead nephropathy may be an important occupational hazard in the United States lead industry.

Aminohippuric Acids↗