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Biomedical subjects

B Wechsler

Publications and source records attributed to B Wechsler.

At least 379 records · Page 21Linked to original sources

[Diagnosis of a fibrosarcoma of the psoas presenting with fever only by gallium citrate scintigraphy (author's transl)].

A fibrosarcoma of the psoas in a 62-year-old woman manifested itself essentially by a febrile syndrome for approximately one year. It would appear that the first manifestation of the lesion occurred three years previously (lumbar pain). Careful clinical examination, numerous radiological studies and two exploratory laparotomies failed to reveal the site of the lesion. The latter was finally demonstrated by GaC67 gammagraphy. This case thus confirms the great value of this radioactive tracer in the diagnostic study of a febrile syndrome as a tumour syndrome. It would appear to be perhaps desirable, in this pathological context, to request a whole body study using GaC67 before proceeding to exploratory laparotomy.

Back Pain↗

[Treatment of hypercalcemia].

Hypercalcemia may have various causes. I should nevertheless be rapidly treated. Among recent treatmens, we may quote diuresis with furosemide, calcitonin, mithramycin, which are the most effective. More recently indomethacin has been used and may be more specific for neoplastic hypercalcemia. These various treatments should be proposed depending on the level of serum calcium, the rapidity of onset and the presumed cause.

Calcitonin↗

[Hypokalemia and hypomagnesemia in a cirrhotic patient. Correction of metabolic disorders by magnesium].

The authors report the case of a cirrhotic with severe hypokalemia (2 mEq/l) responding incompletely to attempts at correction by classical treatments. The findings of a serum and red cell magnesium deficiency led to administration of this electrolyte which proved efficacous. They then recall the mechanism of hypokalemia and hypomagnesemia in alcoholics, study the possible relationship between these abnormalities, their noxious effects and suggest a treatment.

Humans↗

[Periarteritis nodosa and Australia antigen. Comparative study apropos of 25 cases].

The authors compared two series of 27 cases of périateritis over a period of 5 years. The determined the frequency of the nodosa HBs+ (series B) and HBs-- (series A) collected clinical and laboratory signs in both series. There resulted that apart from the hepatic signs constant in series B and absent in series A, the only statistically significant differences were the joint sings and the hypertension more common in series B and the respiratory signs more common in series A. Furthermore, the course of HBs+ cases appears much mote severe than that of HBs-- cases which emphasises the importance of the hepatic involvement but this finding should be interpreted with circumspection for the mode of selection of the patients and the treatment were different in the two series.

Adolescent↗

[Salivary calcinosis and the immunologic context].

On the strength of three new cases, it is suggested that the term "calcifying parotiditis" must be replaced by "salivary calcinosis". This suggestion is based on clinical and pathological grounds. An analysis of 11 cases of salivary calcinosis encountered in the last eight years points to clinical analogies between this condition and Gougerot-Sjögren's disease as well as to the fairly frequent involvement of the immune system in the calcinoses.

Adult↗

[Development and long term prognosis of lupus erythematosus (apropos of 124 cases)].

The authors report their experience of the course of lupus erythematosus. The ten year survival rate in 124 patients was 79.3 %. This good result is attributed to the effective treatment of the disorder using corticosteroids; often associated with ummuno-suppressants in severe cases. However, the side-effects of these drugs remain a source of concern and the ideal treatment for lupus has yet to be discovered.

Adrenal Cortex Hormones↗