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Biomedical subjects

B Wach

Publications and source records attributed to B Wach.

6 recordsLinked to original sources

[Concurrence of lichen planus pemphigoides and ulcerative colitis (author's transl)].

Lichen planus belongs to the group of frequent skin diseases. Therefore, the concurrence with other diseases might be expected by chance. However, the bullous form of lichen planus is a rare disease and for this variant a coincidence with malignant diseases, tumors and systemic diseases, has been reported. Additionally, in the last decade the association of lichen planus respectively lichen planus pemphigoides and diseases accompanied with or caused by immunologic dysfunction has been pointed out. This concerns lupus erythematosus, myasthenia gravis, and ulcerative colitis, diseases, which are accompanied by circulating organ-specific antibodies. A further patient is reported who developed a lichen planus pemphigoides consecutively to an ulcerative colitis.

Adult↗

[Acne fulminans].

Explore the source record for details and available documents.

Acne Vulgaris↗

[Glucose assimilation, insulin secretion and insulin sensititivy in psoriasis patients].

The discussion about a connection between diabetes and psoriasis is picked up again. Serum-values of glucose, insulin and C-peptide after intravenous glucose-load and of glucose and C-peptide after intravenous insulin-load were tested. The level of insulin and C-peptide after i. v. glucose-load was found higher in psoriasis-patients (hyperinsulinism). Considering earlier investigations and new results in diabetes-research (incretin concept), a connection between the two diseases must be denied. The carbohydratemetabolism-deviation in psoriasis could be declared by an enteropathy.

C-Peptide↗

Fasting uric acid and phosphate in urine and plasma of renal calcium-stone formers.

Clearance experiments in calcium-stone patients (n = 60) and controls (n = 60) demonstrated significantly higher urinary uric acid (UA) in younger (less 40 years) stone patients than controls (median: 480 vs. 351 mug/min) but not in older (greater than 40 years) patients. Serum UA and urinary oxypurines were comparable in health and stone disease. Conversely urinary phosphate was significantly lower in younger patients than matched controls (males: 224 vs. 304 mug) and presumably is responsible for the more alkaline pH. It is suggested that calcium-stone formation in humans is represented by two different populations.

Adult↗