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Biomedical subjects

B W Watson

Publications and source records attributed to B W Watson.

At least 37 records · Page 2Linked to original sources

Theory of hydrokinetic clearance of bacteria from the urinary bladder. II. Effects of "bound" organisms and diuresis.

When patients with urinary infection drink large volumes of water and empty the bladder at frequent regular intervals, the concentration of bacteria in the voided samples commonly falls rapidly at first and then remains almost constant. The present theoretical analysis leads to the conclusion that the rapid initial fall in concentration is a function of diuresis and that the subsequent constant output originates from bacteria bound to multiplication sites on the uroepithelium from which their progeny are shed into the urine.

Bacteriuria↗

Electrical potential difference between basal cell carcinoma, benign inflammatory lesions and normal tissue.

Measurement of the resting electrical potential difference on the surface of the skin has been made on patients with suspected basal cell carcinoma. It was demonstrated that in fifty-five lesions from forty-nine patients, the mean electrical potential difference from thirty-six basal cell carcinomas was found to be +II mV, from nineteen benign inflammatory lesions it was found to be +2 mV, and from normal skin, contra-lateral to the lesions in both groups, it was found to be -3 mV. All the measurements are relative to a reference electrode placed under the tongue. The difference between the means for the inflammatory lesions and for the normal skin was found to be statistically insignificant, but the difference between these means and the mean potential difference for the basal cell carcinoma group was found to be highly significant (P less than 0-1%). However, the populations overlap to such an extent as to make the measurement, in its present form, useless as a diagnostic technique.

Basal Cell Carcinoma↗

The Departments of Medical Eelectronics, St. Bartholomew's Hospital--the first ten years.

The organisation of an electronics department required to support the work of a large teaching hospital is described. The research and development programme involves the interaction of graduates from many disciplines since problems can emerge from any of the specialities, for example general surgery, obstetrics and gynaecology, clinical neurophysiology. Examples from the research and development programme of the department are described in order to illustrate the range of medical electronic techniques needed to provide adequate support for the clinical research programmes which have received support from the Joint Research Board of the Hospital and Medical College.

Biophysical Phenomena↗