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B W Low

Publications and source records attributed to B W Low.

33 records · Page 2Linked to original sources

Proinsulin: Crystallization and preliminary x-ray diffraction studies.

Bovine proinsulin has been crystallized under a variety of conditions at both neutral and acid pH. Microtechniques were employed with sample weights of about 200 mug and volumes of 5-20 mul. The crystalline preparations all differ from each other morphologically.X-ray photographs of one form, tetragonal bipyramids grown at pH 3 with added ammonium sulphate solution, established the space group P4(1)2(1)2 (or its enantiomorph P4(3)2(1)2). The cell dimensions are a = 50.8 +/- 0.2 A, c = 148.0 +/- 0.4 A. The asymmetric unit in this form is a dimer of proinsulin which is also the dominant species in solution at this pH.

Animals↗

Deamino-oxytocin and 1-gamma-mercaptobutyric acid-oxytocin: x-ray crystallographic data.

X-ray studies of crystalline deamino-oxytocin (1-beta-mercaptopropionic acid-oxytocin) have established the existence of both wet and dry forms. A remarkable degree of similarity exists between the two forms even though there are changes in cell dimensions and space group on drying. The dry form of 1-gamma-mercaptobutyric acid-oxytocin is very similar to that of deamino-oxytocin.

Butyrates↗