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Biomedical subjects

B Vuković

Publications and source records attributed to B Vuković.

At least 19 recordsLinked to original sources

Radon in the spas of Croatia.

Radon concentrations in air and geothermal water of the spa pools in Croatia were measured and the average values of 40.3 and 4.5 kBq/m3 were obtained, respectively. Great difference between radon concentrations in pool and spring water was considered as a result of mixing normal and geothermal water in the pool as well as the radon decay. Estimation of an effective dose, received by the personnel in the Bizovac spa, gave the value of 0.27 mSv/y. At the location Stubica, the transfer factor of the radon for air and thermal water in the pool was calculated, and the value of 4.9+/-0.7 x 10(-3) was obtained.

Air Pollutants, Radioactive↗

Radon time variations and deterministic chaos.

Radon concentrations were continuously measured outdoors, in the living room and in the basement at 10 min intervals for a month. Radon time series were analyzed by comparing algorithms to extract phase space dynamical information. The application of fractal methods enabled exploration of the chaotic nature of radon in atmosphere. The computed fractal dimensions, such as the Hurst exponent (H) from the rescaled range analysis, Lyapunov exponent (lambda) and attractor dimension, provided estimates of the degree of chaotic behavior. The obtained low values of the Hurst exponent (0 < H < 0.5) indicated anti-persistent behavior (non-random changes) of the time series, but the positive values of lambda pointed out the grate sensitivity on initial conditions and the deterministic chaos that appeared due to radon time variations. The calculated fractal dimensions of attractors indicated more influencing (meteorological) parameters on radon in the atmosphere.

Air Pollution, Indoor↗

[Zoo-anthroponoses in Vojvodina. IV. Epidemiologic characteristics of trichinosis in Vojvodina].

Epidemiological characteristics of trichinellosis in Vojvodina have been analyzed on the basis of registered cases of the disease, registration of epidemics and also epidemiological investigation of exposed persons. In the period 1984-1993, 1802 diseased persons were registered, 958 male and 844 female. Death was registered in one case. Average morbidity was 8.9/10(5). Trichinellosis affects all age groups. At younger age the disease affects both sexes, but in the group over 20 years of age the disease is statistically more frequent in males. During the observed period 70 epidemics of trichinellosis were registered. The main source was the domestic swine. Epidemiologically the greatest risk were domestically produced sausages causing 80% of epidemics. Consequently the season for pork meat preparation is the most significant for trichinellosis. Analyzing the origin of affected meat it has been established that regions of Srem and South-West Backa are considered to be hyperendemic foci. 94.3% of epidemics were caused by affected meat from these regions.

Female↗

[Zoonoses in Vojvodina. II. Epidemiologic characteristics of leptospirosis in Vojvodina].

On the basis of reported cases of sickness--death due to leptospirosis and the epidemiologic investigation of 38 sick individuals, epidemiologic characteristics of anthropozoonosis in Vojvodina were analyzed. It has been established that this disease is registered in the form of individual cases, mostly in persons belonging to the productive population. Infection usually happens during the summer months and due to contact with contaminated water. High lethality and antibodies of leptospirosis icterohaemorrhagiae in 55.3% of samples of the serum of the sick point to the fact that only clinically severe forms of the disease were registered.

Female↗

[Zoonoses in Vojvodina. III. Results of a seroepidemiologic study of leptospirosis in Vojvodina].

2697 persons professionally exposed to leptospira working in contaminated waters and grounds or due to contact with infected animals or their products were seroepidemiologically examined. It was established that the presence of leptospirosis in certain categories of examined persons is three to more than ten times higher in relation with it's presence in the control groups. The most frequent serotype was Leptospira pomona. None of the seropositive persons gave data about having leptospirous infection which might be the consequence of asymptomatic infection or unidentified and not registering of the clinically manifested diseases.

Adolescent↗

[Rubella in Vojvodina. VI. Serologic status of women of reproductive age during the time of endemic manifestations of rubella 1978-1985].

In first phase of a study on congenital Rubella syndrome incidence in Vojvodina population, we examined serologic status of 1225 non-pregnant and 846 pregnant women of generative age, as well as the level of exposure to the Rubella virus. On the basis of antihemagglutinin antibody titre 93.2% of women were found to have antibody titre level above or equal to 1/8. There were no significant differences between the proportions of seropositive women in different age groups (x2 = 1.20; P = 0.88). The percentage of seropositive women varied from 82 to 97% (x2 = 29.85; P = 0.005), according to the year of the investigation. The lowest percentage was registered (1980). Rubella virus susceptibility index was 13.1%. On the basis of proven seroconversion the examination of even Rubella serum samples showed the morbidity rate of 7.18%. The level of exposure of pregnant women to the Rubella virus was 71.0%, during all the period of pregnancy. In such circumstances total Rubella morbidity of pregnant women was 2.13%; the highest level, 21%, was in persons form 18 to 19 years of age. It was not possible to make an analysis of pregnancy outcomes and the consequences in pregnant women.

Adolescent↗

[Epidemiologic characteristics of Lyme borreliosis in Vojvodina].

In the period 1988-1992 in the region of Vojvodina diseases caused by Borrelia burgdorferi were investigated for the first time. This investigation encompassed 398 persons with tick bites. There were 340 clinically healthy and 58 affected by Lyme borreliosis. Lyme borreliosis was registered in all age groups. The youngest patient was 5 and the oldest 75. Erythema migrans, clinical disease marker, was found in 94.8% of affected persons. Rheumatic disorders--arthralgiae were found in 3.5% and Sclerodermia circumscripta in 1.7%. Antibodies to Borrelia burgdorferi antigen were found in 46.9% of 32 patients tested by IFA test. In 55 (94.8%) patients the infestion took place in region of Vojvodina.

Adolescent↗

Thoron activity level and radon measurement by a nuclear track detector.

Radon activity concentrations in the air were measured with LR-115 nuclear track detectors at three locations in Osijek. The respective equilibrium factors and the effective dose equivalents were determined. Indoor concentrations were from 9.8 to 58.2 Bq m-3 and relative errors of the track etching method were near 19 per cent. The indoor alpha potential energy of the radon and thoron progenies was measured with an ISD detector. Independent measurements, performed with a Radhome semiconductor detector, showed that the indoor thoron concentration was nearly 20 per cent of the radon one.

Air Pollutants, Radioactive↗

[Post-vaccination reactions and complications of pertussis, diphtheria and tetanus vaccines].

Clinical manifestation of postvaccinal reactions and complications and the presence of sensibilizating antibodies to certain components of the applied vaccines was analyzed in 80 children immunized by Di-Te-Per, Di-Te or Te vaccine. Most children showed a mild reaction; concerning statistical significance it was most frequently limited to the site of the vaccine application if the immunization was performed by Di-Te and Te vaccines, as compared to the immunization by Di-Te-Per vaccine. Indirect basophil degranulation test revealed that 50% of the analyzed reactions were of allergic origin. Sensibilizating antibodies to pertussis antigen are statistically significantly more frequent than to other vaccinal antigens (diphtheria and tetanus toxoids) and additives contained in the vaccines (methiolate, sodium benzoate).

Child↗

[Epidemiologic characteristics of viral hepatitis. II. Hepatitis A in Vojvodina].

In Vojvodina, Hepatitis A occurs endemoepidemiologically. The most intensive epidemiological process takes place in schools, so the specific morbidity of the age group of 7-14 years of age is 4.6 times greater in relation to the average value. The results of bacteriological investigation, as well as those carried out on the pulps of the fingers of pupils of all ages, indicate a high degree of fecal contamination of school environment both in urban and rural communities. The high incidence of asymptomatic infections (1:18), causes the late detection of epidemics, while the inadequate maintenance of personal and general hygiene makes their occurrence and spreading possible.

Adolescent↗

[Ecological characteristics of viral hepatitis. III. Hepatitis B in Vojvodina].

The significance of particular risk factors for hepatitis B virus infection in persons of various ages was analyzed by active epidemiological investigation. Among the diseased children, the largest number of them were mentally retarded and accommodated in special institutions. Sexual and professional exposure to the hepatitis B virus is responsible for a considerable percentage of diseased adults, aged 20-49. In persons over 50 years of age, parenteral medical interventions are the most frequent risk factor. By carrying out proper sterilization in medical practice and vaccination of the exposed categories of the population, a significant reduction of the hepatitis B morbidity rates can be achieved.

Adolescent↗

[Clinical manifestations of acute Q-fever].

The participation of asymptomatic infections and clinical forms of acute Q-fever were analysed, using the active epidemiological investigation of the population affected by Q-fever epidemics. Out of the total number of registered Q-fever cases, the asymptomatic infection was present in 8.36%. The occurrence of asymptomatic infection was statistically more frequent by significance in women than in men. Pulmonary form of Q-fever occurred in 65.20% of the diseased. This clinical manifestation was statistically more frequent by significance in men than in women. The difference between the morbidity rates of Q-fever in regard to sexes could be caused by both the difference in the intensity of exposure to the infection and the difference in clinical presentation and recognition of the disease.

Acute Disease↗

[Epidemiologic characteristics of viral hepatitis. I. Analysis of registered cases of viral hepatitis in Vojvodina].

According to reported morbidity rate, viral hepatitis still represents a major epidemiological problem in Voivodina, as well as in the entire country, although some of the epidemiological features of these diseases are changing in the course of time. The present paper contains an analysis of morbidity, changes in the age distribution, the degree of differentiation of the viral hepatitis, participation of hepatitis A and B in the total number of the differentiated cases, as well as their seasonal occurrence.

Adolescent↗

Role of rec genes in SOS-induced inhibition of cell division in Escherichia coli.

The inhibition of cell division induced by bleomycin (BM) and UV irradiation in the set of rec mutants of E. coli K12 was studied. Data presented in this work indicate that BM treatment requires mainly the RecBC pathway for the induction of cell filamentation. In the recB21 mutant cell filamentation is delayed and reduced compared to the wild type. Cell filamentation is BM-induced with similar kinetics in strains with a proficient RecBC recombination pathway (rec+, recF143 and recN262), as well as in the strain with a fully expressed RecF pathway (recB21recC22sbcB15). Induction is completely abolished in the recB21recF143 double mutant. On the other hand cell filamentation was induced similarly by UV irradiation in all strains with a functional recF gene and in the strain with a fully operative RecF pathway, but it was delayed in the recF143 and recB21recF143 mutants.

Bleomycin↗