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Biomedical subjects

B Velimirovic

Publications and source records attributed to B Velimirovic.

41 records · Page 3Linked to original sources

Plague and Glasnost. First information about human cases in the USSR in 1989 and 1990.

In October 1989 the first case of plague death in the USSR was reported to WHO. This occurrence in man did not surprise plague experts. The country has extensive enzootic areas and the persistence of natural foci, which can be silent for many years, has been well studied. It is known that the plague bacillus can survive and multiply in the soil of rodent burrows and restart local or more extensive transmissions in carrier animals. Isolated cases in man can remain accidental or they may signal a larger epizootic outbreak. The official policy of the comprehensive antiplague services was to eradicate the natural foci by antirodent activities which proved impossible. The present report from the Central Asian part of the USSR in the wake of Glasnost augurs well for the surveillance of plague worldwide as for a period of over fifty years the occurrence of cases in man in this country had been denied.

Animals↗

Toxoplasmosis in immunosuppression and AIDS.

Reactivation of chronic, latent infection of Toxoplasma gondii has been observed previously in transplant patients and malignancies treated with immunosuppressive drugs. Recently it has emerged as the most common recognized central nervous system infection in acquired immunodeficiency syndrome (AIDS) patients, seen in 6-20% of all AIDS cases. It produces diffuse encephalopathy or space-occupying and necrotic lesions. Contrary to classical toxoplasmosis, the serological diagnosis is unreliable and the therapeutical response in most cases is poor.

Acquired Immunodeficiency Syndrome↗

Plague in Vienna.

The history of plague in one city--Vienna, Austria--has been traced from records beginning in the fourteenth century until its disappearance in the eighteenth century. Much of the source material for this review is published for the first time in English and is drawn from records maintained by the city of Vienna at the time of each outbreak. The historical context illustrates the reaction of large populations to deadly disease: fear, helplessness, and acceptance of an ever present threat. Concepts of prophylaxis to ward off the infection were haphazard, empiric, and often dependent on the use of medicaments and treatments that were, in modern terms, irrational. The medical and hygienic concepts of the time were principal impediments to more successful control, as is demonstrated by quotations from official documents dealing with attempts to cope with the epidemic. The development of control measures was painfully slow, and ultimate control was not achieved until socioeconomic improvement and concepts of hygiene both reached the point at which the conditions for the spread of the disease could be minimized.

Austria↗