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Biomedical subjects

B Ujma

Publications and source records attributed to B Ujma.

9 recordsLinked to original sources
PubMed1983

T lymphocytes modifying factors in sera of patients with Myasthenia gravis.

The examination of patients with Myasthenia gravis revealed that before thymectomy the number of T and B cells in the peripheral blood did not deviate from the norm. It was also observed that their sera contained factor stimulating T lymphocytes to the spontaneous rosette formation, theta antigen generation in xynogeneic system and hydrocortisone-resistant thymocytes. No factor inhibiting the spontaneous rosette formation by T lymphocytes or causing the transmission from Thy-1.2+ cells to Thy-1.2-cells was detected in these sera. Thymectomy resulted in the immediate fall of T lymphocytes number in the peripheral blood of the patients examined. Besides, serum of most patients almost totally lost the stimulating factor. The fall of T cells number did not involve the appearance of the inhibitory factor in the patients' serum. Different than in others results gave blood and serum analysis in the patient tymectomized 10 years earlier. Her blood contained the normal number of T and B lymphocytes and the stimulatory factor of a "limited" activity. It displayed only the ability of generating hydrocortisone-resistant cells, it appeared nonactive in generating theta antigen or restoring the ability of rosette formation by T cells.

Adolescent↗
PubMed1982

[Various lipid components in the serum of alcoholics].

In a group of 57 alcoholics, patients of disaccustoming ward, and a group of 61 controls the level of adipose bodies in blood serum was determined. The comparison showed a significantly higher level of cholesterol and triglycerides in alcoholics than in controls. Other lipid components, beta lpoproteides, total lipids and fatty acids exhibited similar values in both groups. The authors analyse, basing on a survey of literature, the expected mechanism of changes responsible for disturbed metabolism of fats in chronic alcoholism.

Adult↗
PubMedDate not supplied

[A case of cerebral form of tropical malaria].

The authors describe a patient with the cerebral form of tropical malaria. The diagnosis was made about one hour after admission to hospital, and owing to this it was possible to start successful treatment with 4-quinoline preparations. The clinical diagnosis was confirmed by examination of stained preparation of peripheral blood. It is stressed that manifestations of acute encephalitis regressed rapidly after administration of 4-quinolines, and that parasitaemia persisted for a long time after regression of the acute phase despite absence of objective and subjective abnormalities.

Adult↗
PubMedDate not supplied

[Effect of tensilon on the behavior of optokinetic nystagmus in myasthenia].

In 14 myasthenics tensilon test was performed together with electronystagmographic recording of optokinetic nystagmus. The mean amplitude of deflections and the mean frequency of nystagmus were calculated before and after intravenous administration of tensilon 10 mg. The results were compared with those obtained in a control group. The test was positive in 11 myasthenics: the amplitude and frequency of nystagmus beats increased and extinction at the end of the test was absent or diminished. In the control group the test was negative, with the exception of 3 cases in which a slight increase in amplitude and frequency was observed. The authors stress the advantages and disadvantages of tensilon test and state that it is diagnostically valuable in myasthenia and myasthenic syndromes in subjects sensitive to the drug.

Adult↗