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Biomedical subjects

B Turner

Publications and source records attributed to B Turner.

At least 91 records · Page 5Linked to original sources
PubMed1980

Cardiovascular effects of hot water immersion (suicide soup).

Deaths from thermal stress have been reported in saunas, diving environments, and now hot spa baths. While investigating the physiological effects of hyperthermic immersion and its application to the therapy of hypothermia, some disturbing physiological anomalies were noted in normal subjects. The effects of standing, cold water immersion and of exercise, each following hyperthermic immersion, were examined. This was a pilot study only but it now seems possible that the ectopic beats may be an effect of the hyperthermic environment rather than the return of cold blood to the extremities, as previously assumed.

Adult↗
PubMed1980

A continuum of care for the inner city: assessment of its benefits for Boston's elderly and high-risk populations.

We describe an approach to health care in the inner city: a multidisciplinary system of physicians and mid-level practitioners that provides individualized care to chronically ill, elderly, homebound, and nursing-home residents of urban Boston who would otherwise be forced into an inappropriate reliance on teaching hospitals. Linked to four neighborhood health centers, three home-care programs, and a teaching hospital, and financially self-supporting except for the home-care component, the system cared for 3000 ambulatory, 280 homebound, and 358 nursing-home patients in the representative year described. In-hospital use, particularly hospital days, was reduced when judged by existing data for comparable (though not identical) populations. Based on stable physician practices, the system offers a workable approach to the related problems of care, manpower, and cost in the urban core.

Age Factors↗
PubMed1979

The role of HLA tissue matching in cadaveric kidney transplantation.

The role of HLA match in donor--recipient selection has been studied in 271 patients who received cadaver transplants during a 10-year period. This series included 36 four-antigen matches, 181 three-antigen matches and 54 two-antigen matches. Our results support the concept that better results can be expected when better matched kidneys are utilized for transplantation.

Cadaver↗
PubMed1979

Water-bone transmission of influenza A viruses?

The isolation of influenza A viruses from unconcentrated lake water and from fecal samples on the shore of these lakes is reported for the first time. Influenza A viruses, representative of most of the major antigenic subtypes, co-circulate in ducks on the lakes.

Animals↗
PubMed1979

Incidence and distribution of venous extension in 70 hypernephromas.

Angiographic, surgical, and pathologic observations of 70 patients with single hypervascular renal cell carcinomas were reviewed. To correlate size and location with extension into the renal veins or inferior vena cava, the tumors were divided into three groups on the basis of size. Of the 32 group 1 tumors (3--5 cm), four showed venous extension. Three involved only the right renal vein, while one extended through the right renal vein into the inferior vena cava. Of the 24 group II tumors (5--7cm), 12 showed venous extension. Only one of these was confined to the right renal vein, while 11 extended through the renal vein into the inferior vena cava. Eight of the 13 group III tumors (greater than 7 cm) showed venous extension. Three of these were confined to the renal vein, while five extended through the right renal vein into the inferior vena cava. This investigation indicates that venous extension is more frequent with tumors of the right kidney and with tumors of larger size.

Adenocarcinoma↗
PubMed1978

Novel influenza A viruses isolated from Canadian feral ducks: including strains antigenically related to swine influenza (Hsw1N1) viruses.

Twelve influenza A viruses, antigenically related to the Ho, H1 and Hsw1 subtypes, were isolated from cloacal samples of feral ducks in Canada. Antigenic comparisons showed that these viruses were most closely related to the recent HSW1N1 isolates from man and pigs, whereas in vivo pathogenicity tests revealed differences between the Hsw1N1 viruses from the ducks and those from humans and pigs. Antigenic characterization of 94 additional influenza A viruses from the ducks showed four haemagglutinin subtypes (Hav1, Hav4, Hav5 and Hav7), an unclassified haemagglutinin, and six neuraminidase subtypes (N1, N2, Neq2, Nav1, Nav2 and Nav5) in various combinations, some of which are novel and have not previously been reported. Three of these duck influenza viruses possessed a haemagglutinin antigenically related to that of classical fowl plaque virus. A much higher percentage of virus isolations were from juvenile ducks (18.5%) than from adults (5%). All of the ducks, from which viruses were isolated, appeared healthy at the time of sampling. Serological studies on a limited number of humans and domestic birds living in close proximity to the Canadian ducks revealed no evidence of interspecies transmission. Our findings suggest that these birds serve as a substantial reservoir of antigenically diverse influenza viruses, including isolates antigenically related to the current human and animal influenza viruses. This reservoir in nature may be perpetuated by a cycle involving annual infection of juvenile birds followed by transmission to the remaining susceptible birds until the next congregation during the breeding season.

Animals↗
PubMed1977

Bone marrow acid phosphatase: another look.

Recent reports have indicated that bone marrow acid phosphatase is the most sensitive test in detecting bony metastases. The experience reported herein suggests that falsely positive results may be common, especially in patients with primary hematologic disorders. A plea is made that caution be given to the interpretation of this test so that some patients will not be denied appropriate therapy and the role of bone marrow acid phosphatase can be better defined by long-term followup in such patients.

Acid Phosphatase↗
PubMed1976

Combined blood cell counting and classification with fluorochrome stains and flow instrumentation.

A multiparameter flow cytophotometer was used to count and classify fixed human blood cells fluorochromed with a mixture of ethidium bromide (EB), brilliant sulfaflavine and a blue fluorescent stilbene disulfonic acid derivative (LN). The system measures light scattered by the cells and absorption at 420 nm for all cells. In addition, nuclear EB fluorescence (540 leads to 610 nm) and cytoplasmic fluorescence from LN (366 leads to 470 nm), brilliant sulfaflavine (420 leads to 520 nm) and EB exicted by energy transfer from LN (366 leads to 610 nm) are measured for all nucleated cells. This information is sufficient to perform red and white blood cell counts and to classify leukocytes as lymphocytes, monocytes, basophils, eosinophils or neutrophils. Light scattering and/or nuclear and cytoplasmic fluorescence values may be further analyzed to obtain the ratio of immature to mature neutrophils. Counts produced by the system are in reasonable agreement with those obtained by electronic cells counting and examination of Wright's-stained blood smears; some discrepancies appear to be due to systematic errors in the manual counting method.

Autoanalysis↗