Search PubMed⌕ Search

Biomedical subjects

B Thomas

Publications and source records attributed to B Thomas.

At least 217 records · Page 12Linked to original sources
PubMed1982

Ontogenetic dynamics of delta-amino-laevulinic acid dehydratase activity in chick embryo organs and the changes in hepatocytes after exposure to lead.

1. The activity of delta-aminolaevulinic acid dehydratase (ALAD [EC 4.2.1.24]) was determined in the liver, myocardium, distal proximity muscle and yolk sac membrane of chicken embryos at 7, 10, 13, 16, 19, 21 and 22 d of age. 2. Maximum ALAD activity was found in the liver on the 10th day, in the myocardium on the 13th day, in the muscle on the 10th day and in the yolk sac membrane on the 19th day. 3. Exposure of hepatocytes cultured in vitro to different concentrations of lead chloride for 1 h showed that maximum inhibition of ALAD activity occurred with 10 and 50 mg Pb/l. 4. Scanning electron microscopy revealed changes in the surface structure of hepatocytes exposed to 10 mg Pb/l.

Animals↗
PubMed1981

Multivariate analysis in glaucoma. Use of discriminant analysis in predicting glaucomatous visual field damage.

A discriminant function obtained in 1978 to separate patients with glaucomatous visual field loss from those without visual field loss was shown to have a predictive value in ocular hypertensive persons as to the subsequent development of visual field loss in five years. A prospective discriminant analysis also was carried out to identify those factors that best separate those in whom visual field defects developed from those in whom they did not.

Factor Analysis, Statistical↗
PubMed1981

Ess-theory for finite populations.

On the basis of some principles from the philosophy of science, the inadequacy of the ESS-theory as introduced by Maynard Smith and Price as a biological theory is discussed, and an improved ESS-theory for finite populations is presented which can adopt the ideas of the original formalism, although modified. Resulting are explicit conditions on the population sizes that ensure certain strategies to be evolutionarily stable.

Biological Evolution↗
PubMed1981

Antiseptic and antibiotic resistance in gram-negative bacteria causing urinary tract infection in spinal cord injured patients.

Fifty-seven isolates of Gram-negative bacterial species from urinary tract infections in spinal cord injured patients were tested for their sensitivity to chlorhexidine, cetrimide, glutaraldehyde, phenyl mercuric nitrate (PMN), a phenolic disinfectant (Hycolin) and a proprietary antiseptic containing a mixture of picloxydine, octylphenoxypolyethoxyethanol and benzalkonium chloride (Resiguard). None of the isolates were resistant to glutaraldehyde, Hycolin or PMN but a substantial percentage were resistant to chlorhexidine (44 per cent), cetrimide (26 per cent) and Resiguard (42 per cent). The resistant organisms were members of the genera Proteus, Providencia and Pseudomonas and they were also generally resistant to five, six or seven antibiotics. Significant correlations were observed between multiplicity of antibiotic resistance and the minimum inhibitory concentrations of the three cationic antiseptics. It is suggested that an antiseptic policy for the bladder management of spinal cord injured patients that relies on the extensive use of cationic agents might lead to the selection of a flora of notoriously drug-resistant species.

Anti-Bacterial Agents↗
PubMed1980

Antiseptic and antibiotic resistance in Gram-negative bacteria causing urinary tract infection.

A collection of 802 isolates of Gram-negative bacteria causing urinary tract infections was made from general practice, antenatal clinics, and local hospitals. The organisms were tested for their sensitivity to chlorhexidine, cetrimide, glutaraldehyde, phenyl mercuric nitrate, a phenolic formulation, and a proprietary antiseptic containing a mixture of picloxydine, octyl phenoxy polyethoxyethanol, and benzalkonium chloride. Escherichia coli, the major species isolated, proved to be uniformly sensitive to these agents. Approximately 10% of the total number of isolates, however, exhibited a degree of resistance to the cationic agents. These resistant organisms were members of the genera Proteus, Providencia, and Pseudomonas; they were also generally resistant to five, six, or seven antibiotics. It is proposed therefore that an antiseptic policy which involves the intensive use of cationic antiseptics might lead to the selection of a flora of notoriously drug-resistant species.

Anti-Bacterial Agents↗
PubMed1979

Nutrient intake.

Explore the source record for details and available documents.

Body Height↗
PubMed1979

Chlorhexidine resistance and the lipids of Providencia stuartii.

The lipid composition of Providencia stuartii has been shown to resemble closely that of Proteus mirabilis. The ability of some Pv, stuartii strains to survive exposure to high concentrations of the antiseptic chlorhexidine could not be explained in terms of differences in lipid content between sensitive and resistant strains. In addition, resistance could not be attributed to either reduced adsorption of the antiseptic or to its gross enzymic degradation.

Adsorption↗
PubMed1979

Emergency surgery for acute hyperparathyroidism: anesthetic aspects.

Hyperparathyroid crisis with hypercalcemia which is resistant to medical treatment, is a rare clinical condition which requires prompt surgical intervention. Preoperative problems, anesthetic management and postoperative evolution are discussed. A case report is described.

Acute Disease↗