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Biomedical subjects

B Taylor

Publications and source records attributed to B Taylor.

At least 199 records · Page 11Linked to original sources

Etched in stone.

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Alabama↗

The specialty match: a necessity in the equitable resident selection process.

For many years directors of Canadian postgraduate specialty programs have selected candidates in an uncontrolled and haphazard way. Candidates and programs alike have therefore been unfairly treated. Since 1986 the Canadian Intern and Resident Matching Service has offered a centrally coordinated matching program to allow candidates to select specialty programs at centres of their choice and program directors to rate candidates. The result has been an effective method to achieve fairness in the selection of postgraduate trainees for participating Canadian specialty programs.

Canada↗

The effect of hypoxia on rat splanchnic prostanoid output.

The effect of hypoxia on isolated perfused rat mesenteric basal venous prostanoid output was studied. Male rat splanchnic vasculature was removed without (SV) or with its end organ (SV + SI) and perfused with Krebs' buffer with a pO2 of 460 or 60 mm torr. Basal splanchnic venous effluent was assayed for 6-keto-PGF1 alpha, TxB2 and PGE by radioimmunoassay at 30, 60, 120 and 180 min of perfusion. Basal output of SV 6-keto-PGF1 alpha was five and ten fold higher than for PGE and TxB2 respectively and comprised 36% or greater of SV + SI 6-keto-PGF1 alpha output. SV PGE and TxB2 output comprised less than 19 and 12% respectively of SV + SI output. Hypoxia decreased SV + SI PG output, 6-keto-PGF1 alpha being most affected. Hypoxia did not alter SV 6-keto-PGF1 alpha output indicating the SI as the anatomic location most influenced by hypoxia. The relative amounts of distribution of PGE or TxB2 output were not altered by hypoxia. These data suggest that there are two distinct areas of splanchnic prostanoid output, the SV and the SI. Decreased 6-keto-PGF1 alpha output might alter splanchnic blood flow at two levels, the splanchnic vasculature, and/or within the bowel wall.

6-Ketoprostaglandin F1 alpha↗

The political role of the health service executive.

The "politicization" of health care in Canada means an increasing political role for health service executives. This article focuses on the political activities and skills required for administrators to become effective in this expanded role. In the 1990s, the administrator must become increasingly externally oriented and proactive. Two externally oriented skills, networking and information processing, are discussed in relation to the current health care environment. Practical examples are provided to illustrate how these skills can be used to ensure both the success of the executive and the position of the organization.

Canada↗

Hopeful signs.

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Delivery of Health Care↗

Complexities of family grief in a burns unit: some social work dilemmas.

Grief is a complex, emotional, but nevertheless normal, natural and painful process which is necessary and common to us all. The intensity of grief is influenced by many factors, e.g., degree of attachment, quality and length of relationship, length and nature of the illness, and whether the death is sudden or expected. Various stages of grief include numbness, disbelief, anger, guilt, remorse, despair, acceptance. In a medical setting the social worker faces dilemmas when involved with family grief, and some of these are addressed herein.

Adolescent↗

Antibiotic prophylaxis in cardiac surgery: serum and tissue levels of teicoplanin, flucloxacillin and tobramycin.

In this study, the pharmacokinetics of teicoplanin have been studied in serum, fat and bone during and after cardiac surgery with two dose (400 and 200 mg) and three dose (400 mg each) regimens in a total of 49 patients. For comparison, 20 other patients, who had received a regimen of flucloxacillin (500 mg qds for five days) and tobramycin (1.5 mg/kg initially then 80 mg tds for three days), were similarly investigated. The lowest mean serum level of teicoplanin during operation was 6.9 mg/l in the two dose regimen and 9.7 mg/l with the three dose regimen. Mean serum levels of flucloxacillin and tobramycin fell to 7 and 1.4 mg/l respectively by the end of operation. At the end of bypass, fat washings contained a mean of 1.2 mg/l of teicoplanin and bone washings a mean of 6.3 mg/l. Mean tobramycin levels were 0.4 and 0.9 mg/l respectively and flucloxacillin less than 1 mg/l in washings from both tissues. The low levels of teicoplanin in fat may explain an excess of Gram-positive sternal infections in the accompanying clinical trial.

Anti-Bacterial Agents↗