Fine needle aspiration biopsy for the diagnosis of secondary amyloidosis.
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Amyloidosis↗
Biomedical subjects
B Stenkvist
Publications and source records attributed to B Stenkvist.
Flow cytometry and interactive image cytometry in endometrial carcinoma. A comparative and prognostic study.
Comparative DNA measurements were performed in 139 women with endometrial carcinoma using flow cytometry (FCM) and interactive image cytometry (ICM). Ploidy level and the percentage of S-phase cells were determined by FCM and ploidy level and the percentage of cells with a DNA content exceeding 2.5c, 3c, 4c and 5c, respectively, were calculated by ICM. The aim was to compare ploidy level obtained by the two methods and to evaluate the prognostic value of all the above-mentioned parameters. Recurrence or residual disease after completing treatment were used as end-points. Follow-up time was 18-48 months. An agreement was obtained in 85% of the cases as regards ploidy level, but in 15% the tumors were regarded as near-diploid by one method and as grossly aneuploid by the other. Both ploidy level (both methods) and S-phase rate (FCM) were correlated with histopathologic grade (p less than 0.001 and p less than 0.05, respectively). In univariate analysis, ploidy level (obtained either by FCM or ICM) correlated with recurrence rate, with a more favourable prognosis for near-diploid cases. When using multivariate models (Cox analysis) including clinical variables, ploidy level by FCM (but not ICM) was still significant as regards prognosis. In the multivariate analysis, S-phase fraction (as measured by FCM) also yielded independent prognostic information. In a separate analysis the proportion of cells with a DNA content greater than 5c gave independent prognostic information besides that of the S-phase fraction and ploidy level. We conclude that measurements of the percentage of cells exceeding 5c give prognostic information beyond the information obtained from flow cytometric determination of ploidy level and S-phase fraction.
Aged↗
A computerized recording system for cytopathologic diagnoses.
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Computers↗
The imprint method for the cytodiagnosis of lymphadenopathies and of tumors of the head and neck.
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Adenoids↗
Membrane properties of lymphatic cells in fine needle biopsies of lymphomas. I. Cap formation after exposure to fluorescein conjugated concanavalin A.
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Binding Sites↗
Transnasal aspiration biopsy of central skull base destructions.
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Biopsy, Needle↗
Evidence of a modifying influence of heart glucosides on the development of breast cancer.
Patients on digitalis medication at the time of diagnosis of breast cancer seem to develop tumors that have a lower growth potential than do patients not on such medication. These tumors are photometrically characterized by small nuclei with lower DNA-RNA content and less variation in morphometric characteristics.
Breast Neoplasms↗