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Biomedical subjects

B Stein

Publications and source records attributed to B Stein.

At least 199 records · Page 11Linked to original sources
PubMed1976

Correlation of behavioural inhibition or excitation produced by bromocriptine with changes in brain catecholamine turnover.

The dopamine agonist, bromocriptine, produced either inhibition or stimulation of motor behaviour in rats depending upon the dose and time after administration. Stimulation of motor activity occurred only with high doses after a 1-2 h delay. Both inhibition and stimulation were associated with decreased turnover of dopamine in the brain. Release of noradrenaline in brain and noradrenaline plus adrenaline in adrenal varied with motor activity. It is suggested that low doses of bromocriptine inhibit behaviour by activating an inhibitory presynaptic receptor, resulting in reduced synthesis and release of dopamine, whilst high doses cause behavioural excitation by activating the post-synaptic dopamine receptor.

Animals↗
PubMed1975

[Minimal brain dysfunction and social class (author's transl)].

The dependence of early occuring minimal brain dysfunction on the standard of living was tested. 1355 6-15 year old patients with psychosomatic and psychiatric disorders were examined and divided into the 3 groups: "no brain dysfunction", "suspected brain dysfunction" and "brain dysfunction" (diagnosed medically). A highly significant correlation between brain dysfunction and a low socio-economic status--evaluated in terms of living conditions and the fathers occupation--was found. A similar dependence of both, early mortality and morbidity on the living standard of different groups of the population is described in the literature.

Adolescent↗