Biomedical subjects
Publications and source records attributed to B Stebbing.
After more than 20 years the extended pedigree of the only known kindred carrying the low frequency antigen Ria (Ridley) was reinvestigated. It is established that Ria is governed by a gene which is part of or very closely linked to the MNSs locus. Further serological and frequency studies are reported.
Two families are described which clearly show that the low frequency antigen Evans is a part of the Rh system, in which it defines a 'new' gene complex.
The second Pt(a+) family is described. Pta is shown to segregate independently from several genetic markers.
A new low frequency antigen, Rba, has been found in three blood donors. Studies on their families show that the antigen is inherited as a Mendelian autosomal dominant character. Rba segregates independently from ABO, MNSs P1, Rh, Kell, Duffy, Kidd, ACP1 and PGM1. Anti-Rba is not common in sera containing multiple antibodies ot low frequency antigens.