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Biomedical subjects

B Srp

Publications and source records attributed to B Srp.

At least 37 records · Page 2Linked to original sources

[Antibiotic prophylaxis in cesarean section].

Childbirth by Caesarean section is associated with 7-10x more complications than spontaneous childbirth [28] whereby the second place is held by infection. One of the possible ways how to prevent these infectious complications is antibiotic prophylaxis. Views on the latter still differ as regards selection of the antibiotic, its effectiveness, onset of administration, dosage, period of administration etc. Prophylaxis should meet the following demands; it should be aimed, of short-term character, bactericide and non-toxic-these demands are met by cephalosporins of the second generation [11]. The objective of the present work was to evaluate the contribution of the prophylactic administration of antibiotics, i.e. a cephalosporin of the second generation-Zinacef (Cefuroxime). The group was formed by 23 women to whom a dose of Zinacef was administered after childbirth by Caesarean section and subsequently twice after 8-hour intervals (1.5-0.75-0.75 i.m.). The control group (23 women) did not have this prophylaxis. In both groups the authors compared the indication of s.c., time of loss of amniotic fluid before s.c., results of cultivations from the cervix, vagina, amniotic fluid, lochiae and sutures. The authors evaluated the postoperative course where they were interested in infectious complications, the temperature curve, period of hospitalization, the necessity to administer another antibiotic or to proceed with the antibiotic therapy after the prophylactic dose. The results are clearly in favour of the prophylactic administration of antibiotics to the risk group of patients delivering by Caesarean section.

Adult↗

[Analysis of estrogen levels in the urine of pregnant women using liquid chromatography].

The gas chromatography estimation using CHROM IV device enables a simultaneous investigation of oestrone, oestradiol and oestriol in urine. It is possible to use sorption on a solid sorbent PRESEP C 18 TESSEK for steroid extraction from biological material which shortens and simplifies the investigation method. The oestriol results gained by the described technique are compared with the values of total oestrogens estimated by the classical fluorometric method after Ittrich. The linear regression analysis gives the following result: Y = 0.7637x-2.7531, r = 0.9431, p less than 0.001 and confirms the correlation of both methods.

Chromatography, Liquid↗