Search PubMed⌕ Search

Biomedical subjects

B Somaini

Publications and source records attributed to B Somaini.

46 records · Page 3Linked to original sources

Inefficacy of the commercial live oral Ty 21a vaccine in the prevention of typhoid fever.

The efficacy of the live oral typhoid fever vaccine Ty 21a marketed in Switzerland in 1981 was investigated. Forty-seven Swiss travellers to Third World countries contracted typhoid fever in 1982 and 1983; 20 (43%) of these persons had been vaccinated with Ty 21a. The incidence of typhoid fever in vaccinees was 1.1 per 10,000 doses of Ty 21a vaccine sold, which was similar to the incidence of 0.9 per 10,000 doses for the ineffective killed Ty 2 vaccine. Comparison of the incidence of vaccination in patients with typhoid fever in 1983 and in healthy travellers to India revealed vaccination efficacy rates which were not significantly different from zero. It is suggested that Ty 21a vaccine in the form marketed in Switzerland in 1981-1983 is not sufficiently potent or heat-stable, so that the doses of viable bacteria ingested were too low.

Administration, Oral↗

[Teaching social and preventive medicine to pharmacy students].

The new Swiss reglementation for the final examination of students in pharmaceutics make social and preventive medicine a mandatory part of the curriculum. The number of hours attributed to the new subject differ markedly between the various schools of pharmacy. They are influenced by the attitude of the institutes and faculties (schools), professional societies but also by the students involved. The experiences of the first year are briefly discussed. Most important is to use the opportunity to improve the collaboration between the different partners in health care.

Curriculum↗

[AIDS in Switzerland].

Around 4000 cases of AIDS (acquired immunodeficiency syndrome) have been recorded worldwide. In Switzerland 18 cases has been reported to the Federal Office of Public Health up to February 1, 1984, of whom 15 were men and 3 women. Up to now 16 of the patients have died. 9 of the people involved were homosexuals and 6 Africans, but none of them was a haemophiliac or drug addict. Four patients were not in a definable risk group. Most of the AIDS patients had stayed in the USA, Haiti or equatorial Africa before falling ill. Pneumocystis carinii pneumonia was found in 9 of 13 Swiss patients, and Kaposi sarcoma in 5 homosexuals and three African patients. The T-helper/T-suppressor ratio proved to be pathologically reduced in all patients in whom this investigation was carried out.

Acquired Immunodeficiency Syndrome↗