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Biomedical subjects

B Shearer

Publications and source records attributed to B Shearer.

5 recordsLinked to original sources
PubMed1985

Outer surface changes of Pseudomonas aeruginosa in relation to resistance to gentamicin and carbenicillin.

The outer surface structure of clinical isolates of Pseudomonas aeruginosa resistant to carbenicillin or gentamicin or both was studied by thin-section electronmicroscopy and compared with that of sensitive isolates. The latter had a fairly smooth outer layer. Strains resistant to both antibiotics were characterised by extrusions that appeared to constitute extensions of the outer membrane. The outer membrane appeared wavy with distortion of its tripartite structure. The latter findings were also present in isolates resistant to only one of the two antibiotics. The disorganisation of the outer membrane might contribute to the expression of resistance.

Acetyltransferases↗
PubMedDate not supplied

Grateful Med: getting started.

When a local medical library is not available, it is often necessary for physicians to discover alternate ways to receive medical information. Rural physicians, particularly, can make use of a computer program called Grateful Med that provides access to the same literature available to physicians in large cities. This program permits the user to perform database searches on the National Library of Medicine database (MEDLINE), corresponding to the primary index to medical literature, Index Medicus. In this article, we give the procedure for procuring a National Library of Medicine password and for making efficient use of the Grateful Med program.

Computer User Training↗
PubMedDate not supplied

A primer for users of medical bibliographic databases.

A database is electronic information. Perhaps one of the most important information sources in medicine is that which is accessed electronically through a database named MEDLINE, the core medical literature published since 1966. MEDLINE is sold by three major vendors (BRS, Dialog, and the National Library of Medicine) to information experts and to medical experts. Information experts (librarians) and medical experts (physicians) can access MEDLINE by two different methods. This article discusses both and emphasizes use by the medical practitioner. An annotated guide to database vendors is provided, and guidelines are offered that will assist the physician in selecting equipment and assessing services.

MEDLARS↗