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Biomedical subjects

B Segal

Publications and source records attributed to B Segal.

At least 55 records · Page 3Linked to original sources

Progression of isolated aortic stenosis: analysis of 29 patients having more than 1 cardiac catheterization.

Factors related to progression of nonrheumatic aortic stenosis (AS) were analyzed in 29 adult patients who underwent serial hemodynamic studies over a mean of 71 months. AS was congenital in 8 patients and degenerative in 21. The patients were divided into 2 groups on the basis of the change in aortic valve area between the 2 studies. Twelve patients had a greater than or equal to 25% reduction in aortic valve area (Group I) and 17 patients had less than 25% decrease in aortic valve area (Group II). There were no significant differences between the 2 groups in age, interval between studies, cardiac output, left ventricular end-diastolic pressure, left ventricular peak systolic pressure and origin of AS (congenital or degenerative). Group I patients had significantly larger initial aortic valve areas than did Group II patients (1.3 +/- 0.9 cm2 versus 0.8 +/- 0.4 cm2, p = 0.02). Also, the initial peak transaortic pressure gradients were lower in Group I than in Group II (27 +/- 19 versus 58 +/- 38 mm Hg, p = 0.01). Group I patients had a significantly greater increase in pressure gradient and a greater reduction in cardiac output than did Group II patients (24 +/- 21 mm Hg in Group I versus -0.1 +/- 24.5 mm Hg in Group II, p = 0.01, and -1.0 +/- 1.3 liters/min in Group I versus 0.10 +/- 1.4 liters/min in Group II, p = 0.03). Thus, AS progressed in 41% of a selected group of patients who underwent repeated cardiac catheterization.(ABSTRACT TRUNCATED AT 250 WORDS)

Adolescent↗

Development of a competency-based training curriculum for substance abuse counselors in Alaska.

The development of a comprehensive competency-based substance abuse curriculum is reviewed and described. The curriculum, which is designed to help persons to further their understanding of alcohol and drug abuse, and/or to help strengthen counseling skills, can be adopted to meet a wide variety of delivery methods. The curriculum, which can be delivered at a university or within a treatment setting, offers a flexible and innovative way of providing substance abuse training to alcohol and drug workers and to those in health and health-related professions.

Alaska↗

Psychological aspects of drug-taking behavior.

A review of recent research identifying antecedents and correlates of drug-taking behavior is presented, together with a brief discussion of their implications for prevention of drug use. Emphasis is given to the need to perceive drug-taking behavior as a multidimensional phenomenon, in which the choice of drug, personality, and social factors, among many other variables, need to be interrelated. The efficacy of an interactionist approach is presented as a means of furthering an understanding of drug-taking behavior.

Humans↗

A factor analytic study of the relationship of experience seeking and trait anxiety to drug use and reasons for drug use.

The relationship of measures of sensation seeking and trait anxiety to drug use and reasons for drug use was studied among a sample of 92 detained or adjudicated adolescent males in a residential detention facility. Experience seeking was found to be related to drug use in general, and especially use of "hard" drugs. Anxiety tended to be related to drug avoidance, except in the case of marijuana and alcohol use. Reasons for drug use which related with experience seeking were excitement and thrill oriented, whereas reasons associated with anxiety were related to feelings of discomfort for this sample. In general, experience seeking was a stronger factor than trait anxiety in these findings. Implications for more action-oriented and less insight-oriented treatment are discussed in light of these results.

Adolescent↗

Alcohol and alcoholism in Alaska: research in a multicultural and transitional society.

Working and living in Alaska, where social and cultural transitions are taking place, allows one the opportunity to reflect on the methods and procedures involved in one's discipline and/or research orientation. This article thus provides a review of what is happening in Alaska with respect to alcohol use by Alaska Natives and reflects on the issues involved when traditional cross-cultural research procedures are followed. Questions are also raised concerning what the focus of research might be, and suggestions for more culturally relevant research are advanced.

Adult↗

Drugs and youth: a review of the problem.

Recent research concerning motives for alcohol and drug use is summarized and reviewed in the context of seeking common reasons for using alcohol and other drugs. Common motives were found which correlated with both drinking and other drug-taking behavior, and specific motives were also found which were related to use of alcohol, marijuana, and other drugs. The implication of these findings for both primary and secondary prevention efforts is discussed.

Adolescent↗

Patterns of reasons for drug use among detained and adjudicated juveniles.

Self-reported reasons for drug use were examined among a sample of detained and adjudicated juveniles at a state residential facility. By means of a series of factor analyses, three common motives or reasons for using a variety of drugs were identified: (1) an expanded awareness-insight motive, (2) a drug effect motive, and (3) an increased activity motive. No relationship was found between type of offense and drug use. The overall findings suggest that drug use may be a means of coping with stress as well as a means of altering consciousness.

Adolescent↗

Reasons for drug and alcohol use by college students.

Interest in examining more precisely the relationship between specific motives for drug and alcohol use and personality prompted the undertaking of this study. By means of a series of canonical correlation analyses, patterns of self-attributed reasons for drug and alcohol use were interrelated to a battery of individual difference variables drawn from the domains of personality needs, daydreaming and mental style, optimal level of stimulation, and locus of control. The findings indicate that drug and alcohol use are linked to individual differences in a more complex way than is typically studied.

Adult↗

Prediction of college drug use from personality and inner experience.

The purpose of this study was to determine the extent to which subjects comprising substance use criterion groups (nonusers, alcohol only users, marijuana only users, polydrug users) could be differentiated on the basis of theoretically relevant personality and inner experience constructs. The test battery included variable from the domains of needs, daydreaming and mental style, optimal level of stimulation, and locus of control. Separate stepwise discriminant analyses were computed for males and females in order to predict drug-use pattern. The analyses were replicated, and the best set of predictor variables was used to predict classifications in different samples. The results indicate that it is possible to differentiate among the criterion groups in a statistically reliable manner on the basis of well-conceived assessment instruments with an accuracy of 60 to 65%. The consistency of the obtained discriminant results across four different samples suggests that rather than seeking some superordinate personality trait to differentiate substance users from nonusers, a general cluster of variables which may be described under the rubric "hang loose ethic" will best separate the groups.

Exploratory Behavior↗

Chronic pyoderma in splenectomized patient.

This is a report of a case with a chronic peculiar intractable pyoderma. The process started a year after splenectomy because of trauma. In the absence of an apparent other reason, we assume that a relationship exists between the operation and the skin disease.

Adolescent↗

Right heart failure secondary to compression of the right pulmonary artery by a syphilitic aortic aneurysm.

A 68-year-old man presented with right heart failure due to compression of the right pulmonary artery by a syphilitic aneurysm of the ascending aorta. The diagnosis was made by cardiac catheterization and angiography and it was proven by autopsy. This complication is unusual and supports the experimental evidence that unilateral pulmonary obstruction may be responsible for the development of pulmonary hypertension.

Aged↗