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B Schulze

Publications and source records attributed to B Schulze.

140 records · Page 8Linked to original sources
PubMedDate not supplied

[Clinical pedographic radiological findings after basal valgus osteotomy of metatarsal 1--a prospective study].

AIM: This study investigated the influence of valgusizing base wedge osteotomy of metatarsal 1 (MT 1) subsequently on the entire forefoot. METHOD: Pre- and post-operatively 22 cases were investigated between 1998 and 2000 both clinically and radiologically with pedographic analysis in 20 of these cases. RESULTS: According to the Kitaoka Score we could establish preoperative 37 and postoperative 72 out of 100 possible points. Following the MT 1-base wedge osteotomy with a distal soft-tissue procedure, the central forefoot region (MT 2/3) showed reduced pressure-induced pain, unchanged callus development, and reduced maximum load pressure. When the Plus-Index (MT 1 longer than MT 2) could be preserved in the valugusizing MT 1-base wege osteotomy, the metatarsalgia in the central forefoot region not only improved generally, but also the maximum loading pressure was clearly reduced. In cases with a post-operative Minus-Index (MT 1 shorter than MT 2), as well as in those Plus-Index cases undergoing a Keller procedure in the valgusizing base wedge osteotomy, the elevated pressure values in the central forefoot region persisted. CONCLUSION: In valgusizing MT 1-base wege osteotomy with preservation of the Plus-Index (MT 1 longer MT 2), metatarsalgia can be improved and the maximum loading pressure in the central forefoot can be reduced.

Adult↗
PubMedDate not supplied

Serine proteases as mediators of radiographic contrast media toxicity.

Iodipamide, iodoxamine, iothalamate, diatrizoate, and ioxitalamate exhibit a dose-dependent prolongation of coagulation time of global and monospecific functional coagulation tests. This is due to an inhibition of fibrin polymerization induced by these contrast media. Furthermore, a dose-dependent generation of fibrinolytic split products by RCM was found. At low doses, biliary RCM cause hypercoagulation by binding to spontaneously existing fibrinolytic products. Biliary RCM cause a dose-dependent decrease of hemolytic complement activity and decrease of complement factors of C3, B, and, to a lesser extent, C4. Nephrotopic RCM do not show these effects. By crossed immunoelectrophoresis B and C3 split products were not detected after in vitro incubation of iodipamide in serum or EDTA-blood. In contrast, zymosan, inulin, and dextran sulfate incubation of sera readily resulted in Bb and C3b generation. The failure to demonstrate complement split products was not due to artifacts. As a working hypothesis unspecific binding of RCM to blood proteins followed by interference with antithrombin and antiplasmin inhibitor functions is proposed. Possibly other antiproteases might be involved too. This results in a lowering of the clinical manifestation threshold of coagulation and fibrinolysis. The mechanism of complement activation remains unclear, since it is not influenced by EDTA, aprotinin, steroids, or by specific sera depleted of prekallikrein, Hageman factor, C2, and gamma-globulins.

Animals↗