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Biomedical subjects

B Scholz

Publications and source records attributed to B Scholz.

At least 37 records · Page 2Linked to original sources
PubMed1986

Organization of the thymidylate synthase gene of herpesvirus saimiri.

Herpesvirus saimiri codes, unlike most other herpesviruses, for a thymidylate synthase (TS). The TS gene of herpesvirus saimiri is unusual in structure and regulation of expression. It is transcribed into a nonspliced mRNA of 2,190 nucleotides. The single open reading frame of the viral TS gene, instructing a polypeptide of 33.5 kilodaltons, has extensive sequence homology with the corresponding TS coding sequences of human cells and of various procaryotes; the putative polypeptide derived from the nucleotide sequence of the herpesvirus saimiri TS gene is 70% identical with the human enzyme. The untranslated regions of the herpesvirus saimiri TS gene do not share homology with the other characterized eucaryotic or bacterial TS genes. The 5' untranslated sequence has 22 ATG triplets shortly followed by stop codons. The herpesvirus saimiri TS gene, which may be weakly transcribed during immediate early and early times of virus replication, is maximally expressed at the late phase. Various parameters suggest that the TS gene has been acquired in virus evolution by an ancestral herpesvirus from the cellular genome.

Amino Acid Sequence↗
PubMed1981

[Sexual development -- sexual advice -- sexual education -- Paedagogico-psychological aspects in gynaecological practice (author's transl)].

Sexuality of man is conceived as a psycho-physical phenomenon, and in gynaecological practice particular attention must be given to psychogenic components, whenever it comes to disorders of sexual organs and functions. It is also desirable and necessary to attend to patients not only in terms of medical findings and their communication. They also should be offered advice and recommendations. Fears and anxiety should be taken from them regarding their own sexual behaviour and experience and partnership relations. Findings obtained from empirical studies into sexual development together with results of an analysis of expectations and attitudes of gynaecological patients. -- Recommendations are given on how to brief patients, with particular reference being made to group briefing. -- Conclusions are suggested for training and upgrading of gynaecologists under the auspices of the Society of Gynaecology and Obstetrics.

Adolescent↗
PubMed1979

[Common antigen for serological detection of urinary tract infections during pregnancy (author's transl)].

All urinary tract infections cannot be safely detected by bacterial urine testing during pregnancy. Therefore, the question was studied whether detection of antibody to the "enterobacterial common antigen" (ECA) might be important to screening of pregnant women for urinary tract infections. Tests were applied to 202 sera obtained from 42 pregnant women with urinary tract infection, with pathological titres having been recorded from 21.8 per cent.--Detection of antibody to ECA, consequently, is not believed to be helpful in improving diagnosis of urinary tract infections during pregnancy.

Antigens, Bacterial↗
PubMed1977

[Demonstration of antibody-coated bacteria in the urine of pregnant women].

Urinary sediments of 64 pregnant women with significant bacteriuria which has been demonstrated several times before, have been investigated for the presence of antibody coated bacteria. Antibody titers were determined in the corresponding serum samples in addition and the results were compared with the clinical diagnosis. In 50% of pregnant women with pyelonephritis antibody coated bacteria could be demonstrated, while 60% of them had elevated serum titers. Taking into account both results in 80% of the pregnant women the clinical diagnosis of pyelonephritis could be confirmed. Pregnant women with asymptomatically significant bacteriuria never gave positive results, whereas pregnant women with cystitis mainly did have negative results. The demonstration of antibody coated bacteria in the urinary sediments of pregnant women with significant bacteriuria as well as the detection of elevated serum antibody titers with the indirect immunofluorescence technique against the urinary strain were found to be of importance for the valuation of a significant bacteriuria.

Antibodies, Bacterial↗