Search PubMed⌕ Search

Biomedical subjects

B Savić

Publications and source records attributed to B Savić.

At least 19 recordsLinked to original sources

Staphylococcus sciuri as a part of skin, nasal and oral flora in healthy dogs.

The coagulase-negative species Staphylococcus sciuri is widespread in nature and is associated with a variety of domestic and wild animals. However, the occurrence of S. sciuri in dogs has received little attention so far. In the present study, we established the prevalence of S. sciuri in a large population of healthy dogs, and characterized isolated strains. Samples from two mucous membrane sites (anterior nares and mouth), and two hair-coated sites (head and withers) were taken from 122 dogs and inoculated into STS agar, a novel selective medium that was introduced and tested in the study. In total, 116 isolates of S. sciuri were obtained from 488 specimens. S. sciuri was isolated from 56 out of 122 (46%) dogs. The occurrence of S. sciuri in the anterior nares and mouth were significantly higher than those in withers and head. No significant association of S. sciuri occurrence in dogs and factors such as sex, age, and living environment (indoor/outdoor) was found. Out of 56 dogs, which tested positive for S. sciuri, 30 (54%) would have it as a resident flora. Thus, we showed that S. sciuri was frequently present as a part of skin, nasal and oral flora in healthy dogs both as a resident and transient carriage.

Animals↗

Evaluation of polymerase chain reaction, tuberculostearic acid analysis, and direct microscopy for the detection of Mycobacterium tuberculosis in sputum.

Tuberculosis remains a major global cause of morbidity and mortality. There is an urgent need for improved bacteriologic diagnosis of Mycobacterium tuberculosis infection. Three methods for rapid identification of M. tuberculosis in sputum samples (direct microscopy, gas chromatography-mass spectrometry [GC-MS], and polymerase chain reaction [PCR]), were compared with culture on Lowenstein-Jensen medium. Growth of M. tuberculosis was observed in 38 of 145 sputum samples. Detection of acid-fast bacilli by direct microscopy gave a sensitivity of 66% and a specificity of 100%. Detection of tuberculostearic acid by GC-MS gave a sensitivity of 55% and a specificity of 87%. Amplification by PCR of a fragment of the insertion sequence IS6110 gave a sensitivity of 95% and a specificity of 93% compared with culture and a corrected specificity of 99% compared with both culture and clinical data. This study indicates that PCR can be adapted for clinical use and is the method of choice for rapid diagnosis of pulmonary tuberculosis.

Base Sequence↗

[Characteristics of sexual offenders in our data].

By analyzing two groups of sexual delinquents: those which have committed rape, attempted rape or committed rape with murder (the first group) and the commiters of indecent acts (the second group), it was established that the named groups are substantially different in relation to some of the studied parameters. In the first group of delinquents, there is considerably less of those who are married (35.48%), in relation to the second group (73.68%). Indecent acts are most often committed in the apartment of the sexual offender (63.16%), while this is the case in 22.58% of the offences from the first group. The victims of indecent acts were only minors. In both groups the most frequent psychiatric diagnosis was psychopathy. Alcoholic state at the time of committing the offence was considerably greater in the first group (87.10%), in relation to the other one (47.37%). There were no important differences relating earlier criminal offences, as well as the psychiatric estimates of accountability between the groups.

Alcoholism↗

[Injuries of the wall of the thorax].

The mortality rate of chest injuries sustained in road accidents stands now at 15-20 per cent. The considerable force of the impact in road accident is, in 60-80 per cent of the cases responsible for chest injuries which involve other organs. Fractures of a single rib needs only analgetica or intercostal blockade. If a rib is broken in several places or if several rib are fractured instability of the chest wall is act to develop in 15-20 per cent of the cases. It manifest itself in paradoxical breathing and ensuing increase in dead space. In these cases required "internal pneumatic splitting" in form of positive pressure surgical stabilisation of the chest wall has regained favour. Wire or plate osteosynthesis screw-less rib plates and steel splints are being used. Primary stabilisation of the thoracis wall is indicated in the cases: with paradoxical breathing, with respiratory insufficiency or in the cases there are other reasons for thoracotomy. In these circumstances surgical intervention ensure that prolonged artificial ventilation and its attendant risks and complications and the demands made on the nursing staff are reduced to a minimum.

Fracture Fixation↗

[The importance of experimental surgery].

Experimental surgery is an integral part of experimental medicine, and by rights should be present especially in the larger medical (clinic) centers that today have yet to be realized. In would provide the cadres that can enlighten scientific projects of fundamental and applicable significance. It would enable experimental research on a number of clinical and operational techniques and technical problems as well as introduce innovative methods and operational procedures. In terms of educating medical and other natural science students, it would open new perspectives for directly including these cadres, during the course of their studies, in the performance of a number of operations. And such experience provides the student with grounds, in a directional sense, for making future life decisions. Thus, experimental surgery could fill a noticeably empty space in the process of student education. The section formed in Novi Sad has obtained appropriate space. There is a keen interest among the cadres. The equipment is on the way toward completion. A surgeon is in charge of this section. During the course of his service as a representative, he will have the opportunity to acquire experience on an international level. This section has already developed a number of functions to perform. It offers cooperation with other similar sections in our country as well as with clinics and cadres interested in working in this field of medicine and surgery.

Education, Medical↗

[Disease of metalgrinding workers (author's transl)].

It is a specific clinical picture with extensive soft tissue gas and swelling of the forearm. Usually, the clinical course is without any other symptoms. Therapy is not necessary because gas disappears in few days. The etiology of the disease is not clear. Gas can be generated by the chemical reaction between a metallic foreign body and tissue fluid. Spread of benzine evaporation has been considered as a possible source as well. The disease is very rare and its knowledge is important in differential diagnosis of gas gangrene.

Adult↗

[Ulcerative tracheo-esophageal fistula--a complication of longterm respiratory support (author's transl)].

A case of ulcerative tracheoesophageal fistula following long term respiratory support is described. After establishing the diagnosis of TEF, an attempt at surgical repair should be made as quickly as patient's condition permits it, ideally immediately. We suggest right side thoracotomy with the resection of the fourth rib, thereby facilitating preparation of a pedicled flap which should be interponated between trachea and esophagus after the closure of the esophagus defect by sutures has been performed.

Adult↗

[Surgical interventions in pacemaker patients (author's transl)].

In this paper 44 operations in patients with cardiac pacemakers have been reported. Electrosurgical instruments were used in almost all cases. It was noted, that neither a disturbance of the pacemaker nor of the heart stimulated by it occured during or after operation. A premature exhaustion of the battery was not observed.

Abdomen↗

[Homotransplantation of the spleen].

A report of experiences and results on 63 homotransplantations of spleen in dogs is given; 50 of the transplantations were performed in an orthotopic and 13 in a heterotopic way. 10 of the latter had undergone an earlier splenectomy and 3 an earlier orthotopic transplantation, followed by a complete resorption of the first transplant. The course of the transplant was observed by scintigraphy, the function of the anastomosis was controlled by angiography. The immunological and hematological changes were analyzed together with the changes of the protein-electrophoresis and those of the fibrinogenic factors. Scintigraphy has proved to be very useful for the diagnosis of transplant rejection; the measurement of the activity of the lysozyme in the serum compared with the pathoanatomical findings showed a characteristic increase of the activity of the lysozyme during the rejection crisis.

Animals↗

[Diagnosis and therapy of pulmonary sequestration (author's transl)].

Pulmonary sequestration is a rare malformation which is characterised by lacking connection to the bronchial system and by atypical arterial blood supply. Unidentifiable tumorous, cystic or infiltrative lung diseases, especially of the lower lobes, should always lead to aortography to exclude pulmonary sequestration.

Adult↗