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Biomedical subjects

B Saunders

Publications and source records attributed to B Saunders.

At least 37 records · Page 2Linked to original sources
PubMed1995

The impact of a brief motivational intervention with opiate users attending a methadone programme.

During the 1980s Motivational Interviewing emerged as one of the memes of the addictions field. This occurred despite the lack of scientific evidence supporting its utility. In this paper findings of a controlled trial of a brief motivational intervention with illicit drug users (n = 122) attending a methadone clinic are reported. Clients who met the study's inclusion criteria were randomly allocated to either a motivational (experimental, n = 57) or educational (control, n = 65) procedure. Over the 6-month follow-up period the motivational subjects demonstrated a greater, immediate, commitment to abstention, reported more positive expected outcomes for abstention, reported fewer opiate-related problems, were initially more contemplative of change, complied with the methadone programme longer and relapsed less quickly than the control group. There was, however, no difference in terms of the severity of reported opiate dependence and the control group fared better on reported self-efficacy. It was concluded that motivational interventions of the type investigated are useful adjuncts to methadone programmes.

Adolescent↗
PubMed1995

Perinatal outcomes in the pregnancies of asthmatic women: a prospective controlled analysis.

Prior studies have found an increased incidence of adverse perinatal outcomes of pregnancies in asthmatic mothers, but these studies have been poorly controlled for asthma therapy and other confounding factors. The purpose of this study was to assess perinatal outcomes in actively managed pregnant asthmatic women as compared with matched nonasthmatic controls. Using an inception cohort design, we studied a volunteer sample of 486 pregnant (< 28 wk) women with documented asthma and 486 pregnant nonasthmatic controls with normal pulmonary function. Cases and controls were matched for age, smoking status, parity, and year of delivery. Asthma was managed with step therapy to prevent acute asthmatic episodes and asthma symptoms that interfered with sleep or normal activity. Chronic hypertension was significantly more common (p = 0.007) in asthmatic subjects (3.7%) than in matched controls (1.0%). However, no significant differences in incidences of preeclampsia, perinatal mortality, preterm births, low-birth-weight infants, intrauterine growth retardation, or congenital malformations were observed in the pregnancies of the asthmatic women as compared with the matched controls. Trends were observed toward relationships between more severe asthma requiring emergency therapy or corticosteroids and increased incidences of preeclampsia and low-birth-weight infants, but these associations were not statistically significant. These data suggest that the overall perinatal prognosis for women with actively managed asthma during pregnancy is comparable to that for the nonasthmatic population.

Adult↗
PubMed1993

Electronic three-dimensional imaging of intestinal endoscopy.

Endoscopists, especially those investigating the colon, need to know where the tip of the instrument is and whether the tube is kinking. A three-dimensional real-time imaging system consisting of sensors, within or taped to the endoscope, to detect weak electric currents in a wire grid below the mattress yields the information needed and should greatly facilitate performance and teaching of endoscopy.

Colonoscopes↗
PubMed1993

Women with alcohol problems: do they relapse for reasons different to their male counterparts?

A sample of 44 women and 50 men attending an alcohol treatment facility were assessed on a range of demographic, social and psychological measures in order to determine whether women and men relapse for different reasons. Clients were monitored for a 3 month period after the initial intake interview whereupon follow-up interviews were conducted. The data were analysed by the use of survival analysis techniques. The results indicated that there were different predictors of relapse across the three levels of post treatment alcohol use investigated. Gender differences were present at two of these levels. The implications of these differences are discussed.

Adult↗
PubMed1993

Guarding the guardians: influencing the regulation of alcohol promotions in Australia.

Alcoholic beverage advertising in Australia is allowed provided it conforms with a Code of Conduct approved by the Media Council of Australia (a collective of media proprietors). This system, known as self-regulation, has come under increasing critical scrutiny. It is argued from a systemic perspective that research has been one factor that has led to this increased scrutiny of alcoholic beverage advertising. Important other factors include the advent of the Australian National Campaign against Drug Abuse (which crucially included alcohol on its agenda), some erosion of the alcoholic beverage producers political status, declining per capita consumption, and an increase in media reporting on alcohol and drug issues. By examination of five research reports recently released on alcohol advertising it is argued that, in order to influence policy makers in an area where there is substantial opposition to change, research must be deftly marketed, contain information of political relevance, such as opinion poll material, and be used as a lobbying tool. The role of researchers in this process is considered.

Adolescent↗
PubMed1993

Ophthalmic assessment of physically disabled children attending a rehabilitation centre.

A retrospective analysis was conducted of 397 children, ranging in age from 2 to 19 years, attending the Regency Park Centre for Young Disabled in Adelaide. The disorders represented included cerebral palsy, head injury, spina bifida, severe speech and/or language disorders, muscular dystrophy and a number of less common conditions. The incidence of significant ophthalmic abnormalities in this population was 51%, with the highest incidence being 69 and 62% among children with head injury and cerebral palsy, respectively. Children with severe speech and language disorders had an incidence of 24%. Overall, routine examinations revealed previously unsuspected significant eye abnormalities in 31% of the children. A complete ophthalmic examination should be part of the evaluation of all physically disabled children to ensure early identification and treatment of abnormalities, and to optimize rehabilitation.

Adolescent↗
PubMed1993

What prevents prevention? Lessons from the failure of a university alcohol and drug policy.

This paper describes an investigation of why an attempt at alcohol and drug problem prevention failed. Between 1986 and 1991 a comprehensive policy on alcohol and drug use was developed in a university in Western Australia. Using a key-informant approach, 26 'players' central to the decision to reject the policy were interviewed, and relevant university documents were examined. The failure of the initiative was found to be caused not only by bad policy formulation (for example, the perceived poor tone of the document, concerns about content and general presentation) but also to bad process. Lack of effective consultation, suspicions about the origins of the policy, distrust and dislike of the policy presenters and concerns about the aim of the policy were cited as major impediments. The central tenet of the policy, that in order to reduce alcohol problems everyone must reduce their drinking, was rejected by most of the decision makers. Perceptions that members of the policy working party were taking an anti-alcohol stance engendered criticisms that the policy reflected the work of 'wowsers' and 'health zealots'. The major lessons learned were that policy formulation, presentation and negotiation are skilled tasks. Preventers need a range of abilities with perhaps the foremost being the capacity to listen to criticism, consult genuinely and implement change slowly. The notion that preventers know what is good for other people needs to be avoided. Preventive policy, if it is to be implemented, has to be introduced by invitation not imposition.

Alcoholism↗
PubMed1992

Drug education: an appraisal of a popular preventive.

Drug education is a popular preventive. In this paper, school-based drug education programs as currently conceived and implemented are critically appraised. The evidence indicates that while such education influences knowledge and attitudes, it has little impact on behavior. It is contended that in most drug education programs the value and meaning of being a drug user is misunderstood and the benefits of drug use underestimated. It is argued that existing health promotion models have in the main failed to adopt a systemic approach to drug use and have focused too much attention on individual change at the expense of a broader social understanding of behavior. It is proposed that with regard to illicit drugs, future educational endeavors should take the form of training in "low(er) risk" drug use within a harm-reduction paradigm, and that with regard to alcohol, such strategies need to be augmented by social and legislative changes. It is concluded that if a harm-reduction and systemic approach is adopted, then education will lose some of its popularity, since such an endeavor will be a more challenging, politically difficult, and socially complex enterprise.

Adolescent↗
PubMed1989

Alcohol and other drugs: the prevention paradoxes.

This paper asks what prevents the prevention of alcohol and drug use problems. Five prevention paradoxes can be identified, all of which may well be interfering with our attempts to reduce the problems associated with drug use. Drug problem preventers should be aware of these paradoxes and, thus, be able to avoid becoming ensnared by them.

Adolescent↗
PubMed1989

Legislative and humanitarian impetus for development of alcohol and other drug policy at an Australian university.

The rationale for comprehensive alcohol and other drug policy at a tertiary institution is presented here as a health promotion strategy for educating University policy makers. Particular emphasis is placed on a discussion of humanitarian issues, that is, the right to a healthy environment, and the potential for legal liability in an environment where alcohol is readily available and other drugs are present. There is little attention paid to drug use related legal issues in the University, but at the same time drawing the attention of policy makers to the organisation's vulnerability to lawsuits has been reported to be a motivating force for adoption of drug use policy. Universities do experience problems related to alcohol and other drug use by staff and students. Problem reduction, and better management of problems, are the major goals of policy in this area. Local initiatives, for example at the organisational level, make important contributions to the overall drug prevention efforts of the nation. Well-developed policy and procedures and effective implementation constitute an important structural health promotion strategy. Such policy would comply with the immediate requirements of Occupational Health, Safety and Welfare legislation and provide some protection against wrongful dismissal claims and negligence lawsuits, as well as providing long-term educative effects. Situations for which policies are needed, range widely due to the University's unique environment and complex roles.

Adolescent↗
PubMed1988

Laterality defects in conjoined twins: implications for normal asymmetry in human embryogenesis.

We evaluated six pairs of conjoined twins: four pairs were dicephalus, and two were of the ischiopagus type. In three of the four dicephalus pairs, the right twin had an abnormality of laterality that included a right aortic arch, reversed great vessel orientation, bilateral right-sided isomerism of the lungs, asplenia, and situs inversus of the viscera. The left twin had normal great vessel orientation and situs solitus in each case. The finding that was unique in these three dicephalus twin pairs was their fused hearts, which were similar in orientation and configuration. The fourth dicephalus twin pair had one normally rotated heart, which was located in the midline and had normally placed chambers and great vessels. Each twin of this pair had normal visceral situs. In the two pairs of ischiopagus twins, each pair had two separate hearts, with normal cardiac structure and great vessel relationships. The viscera expressed normal laterality. Documentation of a defect in laterality in the right twin in three conjoined twin pairs with fusion of the hearts, combined with the presence of normal laterality in three pairs without cardiac fusion, has implications regarding the mechanisms leading to laterality of the human embryo. We suggest that rotation of the heart initiates the embryo's process of lateralization and that the laterality defects of the viscera seen in the right twin are a result of their abnormal cardiac rotation.

Abnormalities, Multiple↗
PubMed1988

Sudden infant apnea and insidious hydrocephalus.

Hydrocephalus secondary to intracranial-intraventricular hemorrhage is a common complication in the clinical course of the high-risk preterm newborn. Hydrocephalus in this population may be insidious without obvious intracranial hypertension. Apnea and respiratory arrest continue to cause concern following nursery discharge of the high-risk preterm newborn. We report a child who presented to the neonatology service with episodes compatible with serious sudden cardiorespiratory arrest. Insidious "non-hypertensive" hydrocephalus was documented as being responsible for these episodes, which resolved with treatment of the hydrocephalus. The perinatal neurosurgical consultant should be aware of this syndrome and instruct the parents and the pediatricians of these infants, who at the time of discharge are asymptomatic but have ventricular enlargement on neuro-imaging studies. The information presented here is of current importance, since most neonatologists are unaware of the syndrome of insidious hydrocephalus.

Apnea↗
PubMed1988

Washout of local anesthetic during arthroscopy.

The recommended dose of lidocaine is often insufficient to obtain adequate local anesthesia when performing knee arthroscopy, particularly in bilateral procedures. A prospective study was conducted to identify the quantity of anesthetic washed out of the knee by irrigation solution. Fourteen patients had knee arthroscopy performed with local anesthetic, either for diagnosis or reparative surgery. Anesthesia was obtained using 20 ml of 0.5% lidocaine injected intraarticularly at the beginning of each procedure, augmented in four cases by an additional 20 ml of 0.5% lidocaine during the procedure. Each of three portals was also infiltrated with bupivacaine 0.25% with epinephrine. Analysis of the normal saline effluent from knee irrigation during the procedure revealed that washout of lidocaine was 50% by weight (range, 42-66%). This percentage did not vary with age, operative time, or quantity of irrigation. We conclude that: (a) safe local anesthesia can be obtained in the average patient with less than the maximum dose of lidocaine, and (b) because of the 50% washout, the safe dose of lidocaine can be increased substantially if needed.

Adult↗
PubMed1986

Correlation of plasma hypoxanthine and catecholamine levels in the umbilical vein.

Hypoxanthine and the catecholamines, dopamine, norepinephrine and epinephrine were determined in umbilical venous cord plasma in 27 term babies delivered vaginally. When correlating hypoxanthine with log epinephrine a weak positive linear correlation was found (r = 0.45, p less than 0.05). The correlation between hypoxanthine and log dopamine showed a significant negative linear correlation (r = -0.65, p less than 0.01). There was also a significant correlation between log epinephrine and pH (r = 0.72, P less than 0.01) and base deficit (r = 0.46, P less than 0.05). In four babies who suffered intrauterine hypoxia, hypoxanthine was significantly elevated compared with non hypoxic babies (21.4 +/- 5.1 versus 6.3 +/- 6.6 mumol/l, P less than 0.01). In these babies norepinephrine (3710 +/- 3888 vs 789 +/- 718 Pg/ml, P less than 0.01) and epinephrine (298 +/- 229 vs 148 +/- 116 Pg/ml, P less than 0.05) were significantly elevated as well, in contrast to dopamine levels (188 +/- 94 vs 169 +/- 134 Pg/ml N. S.). This finding seems to indicate that dopamine synthesis goes down during hypoxia probably because the rate limiting enzyme in dopamine synthesis, tyrosine, hydroxylase, is inhibited in hypoxia.

Catecholamines↗