Search PubMed⌕ Search

Biomedical subjects

B S Thomas

Publications and source records attributed to B S Thomas.

54 records · Page 3Linked to original sources
PubMed1971

Effect of hormonal therapy on plasma testosterone levels in prostatic carcinoma.

Plasma concentrations of testosterone were estimated in normal men, in patients before treatment for prostatic cancer, and in patients who had had various forms of endocrine treatment for prostatic carcinoma. There was no decline in plasma testosterone levels with age. Patients with non-metastatic disease had levels similar to those of normal controls, but in advanced metastatic disease the levels were low. After orchidectomy the plasma testosterone level fell to that found in normal women. In every patient stilboestrol in doses as small as 1 mg three times a day suppressed plasma testosterone at first to negligible amounts, irrespective of the clinical response. Subsequently a small but significant rise in the concentration was always observed over a period of six months' oestrogen therapy. Pituitary ablation with yttrium-90 lowered the plasma testosterone concentration again to negligible amounts in patients who had been on stilboestrol. In advanced metastatic disease this was often associated with relief of pain. Preliminary studies with aminoglutethimide indicate that it can produce biochemical and clinical effects similar to those of pituitary ablation.

Age Factors↗
PubMedDate not supplied

Computer-assisted decision making: a strategy for primary prevention of substance abuse.

A series of six computer-assisted instruction (CAI) programs were developed for primary prevention of substance abuse. The target population, objectives, content, and strategies for the programs were determined from three sources: a literature review of prevention research, theories of learning, and principles of instructional design regarding use of computer technology. Because the focus of the programs is on helping children make responsible choices, the central theme of the programs is on improving decision making.

Adolescent↗
PubMedDate not supplied

Identifying priorities for prepared childbirth research.

Priorities for research on prepared childbirth were identified by means of a statewide Delphi Study. Sample groups of childbirth educators and maternity nurses formulated research topics and set priorities among the topics. Overall, 50 items were specified in four categories: Prenatal Education/Preparation, Labor and Delivery (normal), Postpartum, and Complications. Data were analyzed to identify priorities in each category and to determine the levels of consensus among samples. The need for research on specific areas of prepared childbirth, as perceived by these sample groups, is reported. Although a high level of consensus is apparent, interesting differences emerged.

Delivery, Obstetric↗
PubMedDate not supplied

Efficacy of minocycline as a root conditioner in comparison to citric acid and tetracycline. An in vitro evaluation.

This study compared the root surface characteristics produced by Minocycline HCl, Citric acid and Tetracycline HCl. when used as a root conditioner. This study included 5 groups of 10 extracted teeth each with advanced periodontal disease. Diseased root surfaces of group B,C,D and E were planed with Gracy curets and solutions of Citric acid, Tetracycline HCl, Monocycline Hcl and Tween 80 of PH 2.5, were applied to the surface in respective groups with cotton pellets for 5 mts. Group A was not subjected to root planning or application of any root conditioner and was used as a control. The teeth in all five groups were then washed, sectioned processed and examined under scanning electron microscope. These results revealed that the surfaces of acid treated sites differed from each other and with specimens treated sites differed from each other and with specimens treated with root panning alone. The efficacy of Minocycline and tetracycline in the removal of smear layer and exposure of dentinal tubules were comparable and Minocycline HCl though not as effective as Citric acid can probably be recommended in view of its antibactrial activity, anti collagense and substantivity properties.

Acid Etching, Dental↗
PubMedDate not supplied

A comparison of the fatty acid profiles of subcutaneous fat from women with breast cancer, benign breast disease and normal controls.

Using gas chromatography, the fatty acid profile has been measured in subcutaneous fat obtained from women undergoing biopsy for benign and malignant breast conditions. There was a similar proportion of saturated and unsaturated fatty acids in both types or fat, suggesting that long-term differences in fatty acid constituents of diet are unrelated to risk of breast cancer.

Adipose Tissue↗