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Biomedical subjects

B S Siegel

Publications and source records attributed to B S Siegel.

17 recordsLinked to original sources
PubMed1993

Survival of breast cancer patients receiving adjunctive psychosocial support therapy: a 10-year follow-up study.

PURPOSE: The impact of an adjunctive psychosocial support program on length of survival with breast cancer was evaluated in a retrospective cohort study. The duration of observation of survival was extended 10 years beyond a previous study of the same cohort of patients. PATIENTS AND METHODS: One hundred two nonparticipants were individually matched to 34 participants on major prognostic factors. Both groups were monitored from the date of cancer diagnosis (1971 through 1980) until March 1991. The support program consisted of weekly cancer peer support and family therapy, individual counseling, and use of positive mental imagery. Survival analysis controlled for the effects of other major prognostic factors in the outcome of breast cancer. RESULTS: The mean +/- SD survival time from date of cancer diagnosis to last date of follow-up was 96.0 +/- 53.2 months in the participant group compared with 85.1 +/- 63.4 months in the nonparticipant group, a nonsignificant difference (P = .1). Median survival was 84.0 months for participants (95% confidence interval [CI], 59 to 133) and 66.0 months for nonparticipants (95% CI, 48 to 105). A second analysis restricted nonparticipants to those who had a survival time > or = that of the matched case at time of entry into the support program. Survival increased to a mean of 101.1 months (median, 105.0; 95% CI, 71 to 132) for nonparticipants and remained unchanged for participants, also a statistically nonsignificant difference (P = .9). CONCLUSION: While the program may have beneficial effects on quality of life, this study does not indicate a significant favorable impact on survival with breast cancer or that the program is serving as a social locus for the gathering of exceptional survivors.

Adult↗
PubMed1992

Readers' responses ... medical noncompliance.

The Second Opinion staff invited a number of its readers who are physicians to respond to our recent Case Stories section on medical noncompliance, which included a case story by Kevin Coleman and commentary and overview by Arthur W. Frank (Second Opinion 17, no. 3 [January 1992]). Our thanks to those who shared their reflections, a number of which have been excerpted here.

Attitude of Health Personnel↗
PubMed1990

Agenesis or hypoplasia of major salivary and lacrimal glands.

We described a young man with almost total absence of the parotid glands, hypoplasia of both lacrimal glands, marked hypofunction of both submandibular glands, and left nasolacrimal duct atresia. Lack of tearing, severe dental caries, and conjunctival scarring following chronic xerophthalmia and conjunctivitis serve to alert pediatricians to this autosomal dominant disorder with considerable variation in expressivity.

Abnormalities, Multiple↗
PubMed1990

A comparison of diagnostic outcomes with and without pupillary dilatation.

To compare the quality of fundus evaluations conducted with natural and dilated pupils, 500 typical adult subjects, divided into five age categories, were examined using both techniques. Direct and monocular indirect ophthalmoscopes were used with the natural pupils; direct and binocular indirect scopes were used for the dilated examinations. Retinal anomalies were classified on the basis of posterior pole or peripheral location and whether the anomalies would require significant action by the doctor. Of the 32 posterior pole anomalies which required action, 38% were missed during the natural pupil examination; 51% of the anomalies not requiring immediate action were also missed. These miss rates, along with the 287 anomalies found in the periphery (20 of which required immediate action), suggest that dilation should be strongly considered for all patients so as to optimize the probability of detecting fundus anomalies.

Adult↗
PubMed1985

Helping children cope with death.

When confronted with the death of a loved one, children usually behave according to their developmental level. In the young child, death may be perceived as separation, as the result of magical thinking, or as punishment. Children over six can understand explanations about the cause of death. Parents may seek advice from their family physician about such issues as how the child will react to the death, what the child should be told about death, and whether the child should attend the funeral.

Adaptation, Psychological↗
PubMed1984

The impact of a psychosocial support program on survival with breast cancer: the importance of selection bias in program evaluation.

A retrospective follow-up study was conducted to assess the impact of a psychosocial support program on survival with breast cancer. One-hundred and two nonparticipants were individually matched to 34 participants on several prognostic factors, and both groups were followed from date of cancer diagnosis (1971-1980) until December, 1981. Preliminary findings suggest a strong beneficial effect of the program on survival, which is statistically significant. However, this observed effect is due largely to a selection bias caused by the failure to match on the duration of the lag period between cancer diagnosis and program entry. Correcting for this bias in the analysis results in a small, nonsignificant program effect. We are not able to rule out a possible effect, however, because of the relative lack of statistical power and because of a modest, though nonsignificant benefit observed for women who entered the program shortly after diagnosis. Furthermore, the program might have other beneficial effects on the quality of life.

Adult↗
PubMed1981

Holistic medicine.

Explore the source record for details and available documents.

Attitude to Health↗
PubMed1981

Long-term trends in migratory behavior in a developing country: the case of Mexico.

Comparable lifetime migration relationships are estimated for Mexico for 1950, 1960, and 1970. Moreover, migration flows from each state to every other state are separately examined for each year. A number of significant changes over time are evident in the responsiveness of Mexican internal migrants to various socioeconomic stimuli, and appreciable differences are also evident across space. Moreover, a threshold is observed such that up to about 340 miles higher origin earnings deter migration, but beyond this distance higher earnings actually encourage migration.

Demography↗