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Biomedical subjects

B S Schoenberg

Publications and source records attributed to B S Schoenberg.

At least 19 recordsLinked to original sources

Tapia's syndrome. The erratic evolution of an eponym.

The syndrome first described in 1904 by the Spanish otolaryngologist, Antonio Garcia Tapia, has been variously interpreted by subsequent authors such that there is little current agreement as to the site of the lesion responsible for the condition or the specific symptoms included in this disorder. The confusion arose in part because Tapia's original patient had associated neurologic findings. Careful review of Tapia's reports reveals (1) that he regarded the syndrome as consisting of ipsilateral hemiplegia of the larynx and tongue with normal function of the soft palate and (2) that he believed the lesion resulting in these signs was outside the CNS.

Eponyms

Paralysis of divergence in an adult with aqueductal stenosis: case report.

Paralysis of divergence was observed in an adult with membranous aqueductal stenosis. This association has not previously been reported, although the clinical syndrome of divergence paralysis has been described in several other neurologic disorders, which are reviewed. Recognition of the clinical syndrome of paralysis of divergence is important, since it may occur as an early sign of increased intracranial pressure and since it has been observed in several conditions that are amenable to treatment.

Adult

Moyamoya disease in children.

A review of the recent Mayo Clinic experience with stroke in children having cerebral angiography revealed five patients with moyamoya disease. The disease commonly presents as recurrent strokes and only rarely as a seizure disorder. The angiographic pattern suggests that the telangiectasia characteristic of this condition represents normally present dilated vessels.

Arterial Occlusive Diseases

Cerebrovascular disease in infants and children: a study of incidence, clinical features, and survival.

A 10-year review of the Mayo Clinic experience with childhood cerebrovascular disease unrelated to birth, intracranial infection, or trauma identified 69 patients (38 with ischemic stroke, and 31 with subarachnoid or intracerebral hemorrhage). Although children with cerebral infarction had better survival, they experienced more residual disability than children with cerebral hemorrhage. The medical records-linkage system for Rochester, Minnesota residents made it possible for the first time to study cerebrovascular disease in a well-defined childhood population. Records from all medical facilities serving this population (average of 15,834 resident children) showed four strokes over 10 years (average annual incidence rate of 2.52 cases per 100,000 per year).

Age Factors

The resolution of discrepancies in the reported incidence of primary brain tumors.

Population-based morbidity studies of primary intracranial neoplasms reveal a general pattern of age-specific incidence: a small childhood peak, followed by a taller peak between ages 50 and 80. One notable exception is Rochester, Minnesota, where there is a sustained increase in incidence with increasing age, together with higher age-specific rates than seen in data from other locations. Comparing data from Rochester and Connecticut reveals that the larger percentage of cases first diagnosed at autopsy in Rochester accounts in large part for these discrepancies and suggests that a substantial number of brain tumors remain undiagnosed in the elderly during life.

Adolescent