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Biomedical subjects

B S Jeffery

Publications and source records attributed to B S Jeffery.

5 recordsLinked to original sources
PubMed2000

Pretoria pasteurisation: a potential method for the reduction of postnatal mother to child transmission of the human immunodeficiency virus.

HIV can be transmitted by breastfeeding. The virus is inactivated by heating. A simple and inexpensive method has been devised by which expressed breastmilk may be pasteurised in a domestic setting. The method uses the principle of heat transfer from 450 ml of water heated to boiling point in an aluminum pot to a smaller volume of milk in a glass jar placed into the water (Pretoria Pasteurisation). The aim of this study was to test the reliability of Pretoria Pasteurisation under a range of conditions. Pretoria Pasteurisation was performed using differing starting values for each of the following parameters: volume of milk (between 50 and 150 ml); initial temperature of milk (between 37 degrees C and the ambient temperature); and ambient temperature. Each of the parameters was varied within the range indicated while all other conditions were kept constant. A graph of milk and water temperature against time was constructed with 95% confidence intervals. The ideal temperature range was considered to be between 56 and 62.5 degrees C. Milk temperature remained between 56 and 62.5 degrees C for between 10 and 15 min depending on the combination of variables. The peak temperature and duration of time in the ideal temperature range was minimally sensitive to volume of milk, starting temperature of milk, and ambient temperature. Pretoria Pasteurisation is feasible and reliable under a range of conditions. The method requires refinement and further testing under different conditions.

Breast Feeding↗
PubMed2000

The impact of a pregnancy confirmation clinic on the commencement of antenatal care.

OBJECTIVE: To introduce a pregnancy confirmation clinic as part of antenatal care and to determine whether this would alter the gestational age at which patients commence antenatal care. SETTING: Three municipal antenatal clinics in Atteridgeville and Central Pretoria. METHOD: A pregnancy confirmation clinic was set up at three sites. At the clinic any woman wishing to confirm whether she was pregnant was offered a urine beta-HCG test. If this test was positive, on-site testing for syphilis, anaemia and rhesus status, dipstick testing of the urine, clinical examination and ultrasound examination were performed. Women with abnormal test results were commenced on appropriate treatment immediately and women requiring further medical care or investigation were referred appropriately. RESULTS: The study recruited 382 women, 145 of whom were defaulters from contraception. Half of the women (191) had a positive pregnancy test. The mean presenting gestational age was 12 weeks 4 days (standard deviation 5 weeks, range 5 weeks-25 weeks 2 days). Treatable conditions with the potential to influence pregnancy outcome were identified in 37 of the pregnant women (19.4%) Forty-three of the pregnant women intended to terminate the pregnancy. CONCLUSION: It is possible to shift the commencement of antenatal care to an earlier gestational age.

Adolescent↗
PubMed1989

Phaeohyphomycotic cutaneous disease caused by Pleurophoma in a cardiac transplant patient.

A 56-y-old female cardiac transplant patient treated with cyclosporine and prednisone noted the onset of three nontender red nodules on the legs and arms after gardening. Biopsy of all lesions revealed inflammatory cells and hyphal elements in the dermis. The dematiaceous fungus cultured from biopsy tissue was a pycnidial-forming organism of the genus Pleurophoma. The lesions responded to the topical application of miconazole.

Female↗