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Biomedical subjects

B S Edeiken

Publications and source records attributed to B S Edeiken.

8 recordsLinked to original sources

US-guided implantation of metallic markers for permanent localization of the tumor bed in patients with breast cancer who undergo preoperative chemotherapy.

Metallic markers were implanted with ultrasonographic guidance in 51 malignant breast tumors in 49 patients to tag the tumor bed in anticipation of complete or almost complete response to preoperative neoadjuvant induction chemotherapy before breast-conservation surgery. The markers were the only remaining evidence of the original tumor site in 47% (23 of 49) of the patients preoperatively. This technique effectively addresses the problem of preoperative localization of the tumor bed in complete or nearly complete response of breast cancer to neoadjuvant chemotherapy.

Adult↗

Giant solitary synovial chondromatosis.

The purpose of this report is to describe giant solitary synovial chondromatosis, a previously unrecognized feature of synovial chondromatosis that may histologically and radiographically mimic a malignant neoplasm. Giant solitary synovial chondroma is an intra- and/or extraarticular lesion measuring over 1 cm in size and sometimes as large as 20 cm. The radiographic appearance is that of a large, well-marginated mass either of irregular feathery calcification from coalescence of multiple small synovial chondromas, or a rounded calcified mass from the growth of a single synovial chondroma. Radiographically, giant solitary synovial chondromatosis may appear similar to chondrosarcoma and parosteal osteosarcoma.

Adult↗

Remedial program for diagnostic radiology residents.

OBJECTIVES: We describe a 1-year remedial program for radiology residents with deficiencies in basic medical sciences that cause difficulty in the understanding and application of basic radiologic principles. METHODS: Six of 107 residents participated in the remedial program at separate times during an 8-year period. The design of the remedial program was based on the following: 1) reassignment to first year basic radiology rotations with 1-year delayed advancement to the subspecialty rotations; 2) comprehensive radiology texts that contain a detailed review of related embryology, anatomy, physiology and pathology; 3) instruction in the study of the texts; and 4) repetitive learning accomplished by intermittent reassignment of rotations in which difficulty was demonstrated. Resident performance was evaluated by correlation of monthly written faculty evaluations, the results of the American College of Radiology Intraining Examination, and the American Board of Radiology (ABR) written and oral examinations. RESULTS: During the period of remediation, faculty evaluation revealed improved performance in all six residents from below-average ratings (mean = 2.3) to above-average and superior ratings (mean = 8.3). These results were correlated with the American College of Radiology Intraining Examination scores, which improved from the lowest quartile (range 0% to 28%) to the highest (range 78% to 99%). Each resident successfully passed the ABR written and oral boards on the first attempt. Two additional residents who were offered but did not accept remediation eventually dropped out of the program or repeatedly failed the written ABR examination. CONCLUSIONS: Ultimately, strengthening basic medical science knowledge facilitated interpretation of radiographs by enabling the integration of basic radiologic and scientific principles and understanding the underlying basic medical, radiologic, and clinical significance.

Female↗

Subtle early osteosarcoma.

Seven cases of osteosarcoma in their very early stage of development are presented. With the exception of two cases the tumors were overlooked in the first radiographic examination. Two cases demonstrated increased density, three revealed subtle erosion or lytic destruction, and one case had no definite abnormality in plain radiographs but the computed tomography was abnormal. The value of additional radiographic modalities is outlined. The necessity of a high degree of suspicion for early diagnosis of osteosarcoma is stressed.

Adolescent↗

Slipped proximal humeral epiphysis: a complication of radiotherapy to the shoulder in children.

Slipped proximal humeral epiphyses as a sequela of radiotherapy were identified in two children treated for Ewing's sarcoma in whom the shoulder was included in the field of treatment. The radiation doses were slightly greater than those in children developing slipped capital femoral epiphyses following radiotherapy. The lesser stress about the shoulder compared to the hip is believed to be the reason this is an infrequent complication of radiotherapy.

Bone Neoplasms↗

Radiotherapy changes of the pediatric hip.

Significant radiation-induced abnormalities (aseptic necrosis of the femoral heads, slipped capital femoral epiphysis, radiation-induced sarcoma) were identified in eight of 44 patients aged 16 years or younger at the time of radiotherapy and followed for at least 3 years. The incidence is 18% in the entire group and 25% (8/32) if only patients with radiographs of the hips 3 or more years after therapy are considered. The first evidence of abnormality developed 13 years after irradiation in one patient. The need for long term follow-up of therapeutically irradiated children is stressed.

Adolescent↗