[Electrical stimulation in the treatment of chronic pain].
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Biomedical subjects
Publications and source records attributed to B Rutkowski.
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Since 1972, 367 patients with chronic low-back pain have been treated by electrical stimulation (e.s.). Patients with herniated disc lesions and spondylitis and allied conditions were included. Following e.s. 75-100% pain relief was obtained by 53% of the patients 50% pain relief by 27% and there was no improvement in 20% of patients. In a follow-up of 208 patients, 6-36 months later, approximately 70% stated that pain relief was similar to that obtained at the end of treatment.
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A new form of electrostimulation was investigated in a series of 768 patients with chronic pain. The method is based on the insertion of needle-electrodes in symmetrically selected points of the body and the passage of an electrical current of specified parameters. Treatment sessions last about 15-20 min and are repeated at intervals of 1 to 7 days. The procedure is simple and free from undesirable side effects. The investigation was based on 12000 sessions. The results of the treatment are discussed. No hypothesis of the mechanism of the beneficial effects obtained by electrostimulation is given, though the gate control theory of pain is cited.
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Though it is said that some immunosuppressive agents are implicated in the development of hyperlipidemia in kidney recipients, this subject is still controversial. Main plasma lipid parameters, as well as apolipoproteins A1 and B were measured periodically in 39 kidney first cadaveric, nondiabetic recipients during 24 months of clinic follow-up after transplantation. Standard triple immunosuppressive therapy: prednisone + cyclosporine + azathioprine was administrated from the beginning. After the second year of kidney transplantation, a significant reduction refers to values of TC, LDL, apo A1 and apo B. In the group with antirejection - methylprednisolone therapy, and without it only TG in the 24th month and apo B in the 1st month were statistically lower in the latter group (both p < 0.05). In the multiple regression test, a linear coincidence was observed between apo A1, apo B and prednisone cumulative dosage after the 1st month, TG and cyclosporine in the 6th month and LDL and cyclosporine in the 12th month after transplantation. It appears that steroids had an impact on lipids directly after transplantation, while cyclosporine did so thereafter.