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Biomedical subjects

B Russell

Publications and source records attributed to B Russell.

136 records · Page 8Linked to original sources

An effort to upgrade perinatal nursing practice in Albania.

In 1994 the Jacobi Medical Center in Bronx, New York, and the University Hospital in Tirana, Albania, entered into a partnership designed to upgrade certain aspects of the health care system in Albania. During a 2-week trip, an American contingent of nurses and nurse-midwives worked to increase the knowledge base of Albanian nurses about some of the most important issues in perinatal care and of the roles of nurses and nurse-midwives in the United States as patient advocates and educators.

Albania↗

Comparison of two indices of glycemic control in diabetic subjects: glycosylated serum protein and hemoglobin.

Glycosylated serum protein (GSP) and glycosylated hemoglobin (GHb) were measured in 263 insulin-dependent and 41 non-insulin-dependent diabetic subjects. Both indices provided useful information in type II diabetes, but were extremely poor in judging control in type I diabetes. In both groups, there was poor correlation of the fasting serum glucose with either GSP or GHb. Only 4% of type I diabetic subjects had normal values for both GSP and GHb. Of subjects with elevated GSP, 98% had elevated GHb; 25% of subjects with elevated GHb values had normal values for GSP.

Age Factors↗

Keratolysis following excimer laser phototherapeutic keratectomy in a patient with keratoconus.

PURPOSE: We report a case of keratolysis following phototherapeutic keratectomy (PTK) for a subepithelial nodule in a patient with keratoconus. METHODS: A 29-year-old male with keratoconus who became contact lens intolerant because of a raised subepithelial nodule was treated with excimer laser phototherapeutic keratectomy (PTK). RESULTS: The epithelium failed to heal postoperatively, and progressive keratolysis led to a central descemetocele by the eighth postoperative day. The patient was managed with a penetrating keratoplasty. CONCLUSIONS: Excimer laser phototherapeutic keratectomy has been shown to be an effective treatment for subepithelial nodules in patients with keratoconus. Rapidly progressive keratolysis is a potential complication of this procedure.

Adult↗

Cerebrospinal fluid serology--is its routine use justifiable?

Although neurospyhilis has become a rare disease, requests for cerebrospinal fluid (CSF) syphilis serology tests at the Colorado Department of Health have increased in recent years. Because of the low rate of positive results, questionnaires were sent to the physicians who requested these tests to determine the criteria for their use. Neurosyphilis was neither suspected nor an important consideration to rule out in 63 percent of the 337 patients sampled. Of the patients whose ages were specified, more than half were under age 40. No concomitant reports of blood serology were available for 63 percent of the study patients, and only 13 percent of the available blood serology reports indicated reactivity. One of the two patients with positive test results was appropriately treated, but the other patient for whom the test was ordered 'routinely' to rule out neurosyphilis was lost to followup. One-half of the tests were requested by neurologists, neurosurgeons, and orthopedists. The survey findings indicated that most of the CSF serologic tests for syphilis were done without appropriate preliminary testing for patients who had no evidence of syphilis by physicians who perform lumbar punctures as a consequence of their specialties. The authors recommend that use of the test be reviewed in light of the changing epidemiology of the disease. They further suggest that directors of laboratories performing CSF serologic tests are in a unique position to initiate an educational exchange and a consequent change in physicians' behavior.

Adolescent↗

Erythroleukemia of childhood and infancy: a report of two cases.

Two rare de novo cases are presented of pediatric erythroleukemia (EL), AML-M6 in a four-month-old (patient A) and four-year-old (patient B) African-Americans who presented to the Medical College of Georgia from 1989 to 1995. The clinical, morphologic, immunophenotypic and cytogenetic features of both patients are reviewed. The purpose of this study is to correlate the bone marrow morphology with the immunophenotypes and the karyotypes of the neoplastic cells. The patients were both female, presented with flu-like symptoms, and were noted to have hepatosplenomegaly on physical examination. The peripheral blood examination was significant for anemia (Hb 54 (A), 84(B)g/L), and thrombocytopenia (86 (A), 70(B) x 10(9)/L). The bone marrow contained 75 percent (A) and 76.8 percent (B) erythroblasts and showed myelodysplastic changes in the erythroid cell line. Cytochemical analysis was performed, and greater than 10 erythroblasts per 100 cells were periodic acid-Schiff positive. Immunophenotypes of the pretreatment bone marrow showed glycophorin-A, CD71, and CD11b positivity. The karyotypes of both patients contained complex (> 3 per clone) cytogenetic abnormalities. Our data suggest that the initial presentation and course of disease are different in adults and children. However, once the adult form reaches the acute leukemia stage, the laboratory findings are similar to those at initial presentation in pediatric EL.

Acute Disease↗