Search PubMed⌕ Search

Biomedical subjects

B Rudensky

Publications and source records attributed to B Rudensky.

At least 91 records · Page 5Linked to original sources
PubMed1985

Risk factors for coronary artery disease in 124 Jerusalem medical students.

As part of an epidemiologic teaching exercise, we studied coronary risk factors in two consecutive classes of Jerusalem medical students (n = 124) and calculated a summary coronary risk score for each student. Men were at higher risk than women because of greater body mass, higher blood pressure and more cigarette smoking. Married males were at lower risk than single males because they had lower cholesterol levels and smoked less. Married and single females were at equal risk. Jerusalem students smoked more than most groups of American medical students and less than their European counterparts. There is reason to believe that an exercise of this kind may result in risk-reducing behavior on the part of high-risk students.

Adult↗
PubMed1985

A new temporary synthetic skin substitute.

Eighteen months of experience with a new synthetic temporary skin substitute (Omiderm, Omikron Scientific Ltd., Rehovot, Israel) is presented. The substitute is a thin, transparent, flexible membrane. It is used when a biological dressing would otherwise have been used. Our experience consists of laboratory studies and 75 clinical cases including donor sites application, chronic wounds, ulcers, partial thickness and full thickness burns. The membrane is very elastic, permitting free movement and physiotherapy during the healing process. The material protects the wound and prevents either the accumulation of fluid under it or wound desiccation. It does not interfere with the normal healing process. It reduces pain, prevents bacterial invasion and is very easy to handle. Complications, such as haematoma formation or infection, were quite few. We recommend its use in routine daily practice.

Adolescent↗
PubMed1985

Botulism intoxication after surgery in the gut.

Botulism intoxication is described in a 45-year-old woman who was hospitalized with symptoms suggesting an intestinal obstruction. At intervention a 20-cm length of necrotic small intestine was excised and prophylactic antibiotics were given. Five days after surgery--during which time the patient was fed only parenterally--dryness of the mouth, difficulty in swallowing, general weakness, and difficulty with speech and in keeping her eyes open were noted. The patient was alert and well oriented. The clinical symptoms and the electrophysiological studies suggested the diagnosis of botulism. A serum sample caused death in mice upon inoculation and two samples of feces were positive for the presence of Clostridium botulinum organisms. Supportive treatment with botulinum antitoxin was given and the patient was discharged in good condition.

Anti-Bacterial Agents↗
PubMed1984

Fungal serology in the elderly.

90 geriatric patients without any clinical signs of systemic fungal infection had their sera tested for the presence of candida and aspergillus precipitins and cryptococcal antigens. None of the patients had positive aspergillus or cryptococcal serology. 13% of patients were found to have candida precipitins, but these cases were not significantly correlated with candida colonisation, length of hospitalisation, prior antibiotic therapy, steroid therapy or diabetes. Allowing for 13% false positives, serological testing might be helpful in identifying systemic candidiasis. It is probably highly specific for parenchymal involvement by aspergillus or cryptococcus.

Aged↗
PubMed1983

Cytomegalovirus infection and disease in the Jerusalem area.

We studied the epidemiology of cytomegalovirus (CMV) infection in women and neonates in the Jerusalem area. During the 6-month period from January to June 1982, we recorded the presence of antibody to CMV in pregnant and parturient Jewish and Arab women from West and East Jerusalem, respectively, in 18- to 22-year-old female students at a religious college, in female university students, in 18- to 22-year-old student nurses, and in the nursing staff of the Neonatal Intensive Care Unit in our hospital. In the 18- to 22-year-old age-group, the religious college students not working in a medical setting had the lowest rate of seropositivity. No difference in the rate of CMV infection was found between Jewish and Arab parturient women. In five cases of congenital CMV infection, representing different clinical aspects of the disease, a comparative study of diagnostic procedures for congenital CMV infection was performed.

Adolescent↗
PubMed1983

Epidemiology of group B streptococci in an Israeli hospital.

A technique for the rapid identification and quantification of Group B streptococci (GBS) utilizing timed coagglutination and selective broth media was designed. A prospective study of 283 mothers and 121 newborns based on this methodology revealed a GBS colonization rate of 5.3 and 4.1%, respectively. A retrospective study of 19,875 births revealed a GBS attack rate of 0.2 per 1,000 live births. Both the low colonization and the low attack rates confirm previous anecdotal reports of a low incidence of GBS colonization and disease in Israel. The technique described herein can aid in identifying those infants at risk for invasive disease.

Cross Infection↗
PubMed1983

Surveillance of congenital rubella and the immunity status to rubella in the Jerusalem area.

A retrospective study on the incidence of congenital rubella (CR) in the past 10 years in the Jerusalem area was conducted. After the 1972 epidemic, which resulted in 48 cases of congenital rubella, few sporadic cases of CR appeared each year, and in the 1978-79 period the number of CR cases was relatively small. Immunity to rubella in different categories of population (children 3 months to 18 years, college students, nurses in pediatric, newborn and intensive care units, student nurses, and women of childbearing age) was determined by hemolysis in gel (HIG) and hemagglutination inhibition (HI) methods. Susceptibility was defined as an absence of antibody at a dilution of 1:16 in HI, and hemolysis of less than 7 mm in the HIG test. Compared with previous studies on the incidence of antibodies to rubella in women of childbearing age, a mild decrease in the percentage of sero-negative women was found.

Adolescent↗
PubMed1983

Unusual presentation of Bruton's agammaglobulinemia--Pseudomonas sepsis.

A case of Pseudomonas sepsis and meningitis is described in a family in which the first child died in the first year of life after a fulminant Pseudomonas sepsis. In our patient, the second son, treatment was begun immediately after admission with clinical and bacteriological signs of Pseudomonas sepsis and continued for a 4-week period. Subsequent cessation of the treatment resulted in a relapse, with meningeal involvement. After specific therapy was added for his immunologic incompetence, as well as subsequent antibiotic treatment, the patient was cured of his prolonged illness.

Agammaglobulinemia↗
PubMedDate not supplied

Omiderm, a new synthetic wound covering: physical properties and drug permeability studies.

Omiderm (Omikron Scientific Ltd., Rehovot, Israel), a new synthetic wound covering based on hydrophilized polyurethane, was found to be highly permeable to water. Values in the region of 5000 g/m2 24 h were found for the water permeability of Omiderm in comparison to 1400 and 500 g/m2 24 h for Biobrane (Hall, Woodroof Inc., Santa Ana, CA) and OP site (Smith and Nephew Ltd.), respectively. Permeabilities of antibacterial agents through Omiderm were found to be two to three orders of magnitude greater than those through Biobrane. The in vitro effectiveness of various antibacterial agents in lowering bacterial growth of different bacterial strains were applied to seeded agar plates through Omiderm membrane was investigated. NBH ointment (1% Neomycin, 1% Bacitracin, and 0.5% Hydrocortisone) was found to be the most effective material in inhibiting bacterial growth, except for Pseudomonas aeruginosa where silver sulfadiazine was superior. In in vivo experiments bacterial counts of infected wounds covered with Omiderm and topically treated with NBH were lowered to less than 10(3) organism/g tissue after one day of treatment.

Animals↗