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Biomedical subjects

B Rosengren

Publications and source records attributed to B Rosengren.

At least 55 records · Page 3Linked to original sources
PubMed1980

Transient intestinal ischaemia induced by degradable starch microspheres. Experiments in the cat.

Temporary ischaemia was induced in cat small intestine by degradable starch microspheres. Regional arterial and tissue blood flow immediately fell by 85 per cent with subsequent normalization within 26 min after microsphere injection. Degraded 99Tcm-labelled microspheres were exponentially removed from intestinal vessels and accumulated in the liver. Provided near-total arteriolar obstruction is induced, external isotope detection may permit assessment of the duration of the induced ischaemia, which implies a selection of the appropriate time for radiation therapy.

Animals↗
PubMed1980

Effects of proton irradiation of the lumbar intumescence on intra-axonal transport of acetylcholine and cholinergic enzymes in rat sciatic nerve.

The content and intra-axonal transport of acetylcholine (ACh) and the cholinergic enzymes cholineacetyltransferase (CAT) and ACh-esterase (AChE) in sciatic nerve were investigated in rats following single dose proton irradiation of the lumbar intumescence of the spinal cord with 60 Gy or 200 Gy. One, 7 or 30 days after irradiation nerve-crush operations were performed 12 hours before killing and the levels of ACh and enzyme activities in nerve segments relative to the crushes were estimated by biologic (ACh) or chemical (enzyme) methods. The results indicate that alterations in intraneuronal dynamics of ACh and related enzymes are not a major cause for the development of neurologic symptoms of the motor system after irradiation, and that descending myelinated axons are of minor importance for the regulation of cholinergic substances in rat motor nerves.

Acetylcholine↗
PubMed1977

Immobilization of the eye. Evaluation of a new method in retinal detachment surgery.

Experiments on eye phantoms (closed chambers filled with suspensions of lipoid particles in water) have shown that saccadic rotational movements induce liquid currents flowing back and forth through a hole in a latex membrane mounted inside the chamber. It is postulated that rapid (saccadic) eye movements generate similar motions in the liquid vitreous, capable of moving a detached retina. Sixty-five non-selected eyes with primary rhegmatogenous retinal detachment were immobilized by traction sutures, usually for 2-3 days (range 1-5 days) prior to surgery. An almost complete "spontaneous" reattachment occurred in 45% of the cases, a partial reattachment (i.e. more than half of the detached area) was seen in 37%, but no reattachment took place in 18%. This rate of reattachment is higher than that obtained by bilateral eye patching and complete bed rest. Rapid (saccadic) eye movements are considered to be one crucial factor counteracting retinal reattachment. Eyes, in which preoperative reattachment is achieved, can be cured by simple surgical procedures and have a favourable prognosis.

Adolescent↗
PubMed1977

Retinoblastoma treated with a 60CO applicator.

The 60Co applicator for treatment of retinoblastoma, described in 1963, has the advantage of exact local positioning. It is suitable in cases with solitary small tumours. The complications and the results of treatment in 20 patients followed up for at least 2 years are reported and discussed.

Cataract↗
PubMed1977

The effect of translatory and rotatory movements upon the eye. Their significance in the development of retinal detachment.

It was shown in experimental models that translational movements of a closed chamber do not induce liquid flow in the chamber, but rotational movements do induce a current. It was also demonstrated in the experiments that rotational currents are able to elevate a rubber membrane if there is a hole and that a liquid flow is then passing through the opening. These observations initiated the idea of fixation of the eye in cases of retinal detachment in order to promote a reattachment.

Humans↗
PubMed1977

Active immobilization of the eye in the treatment of retinal detachment.

40 eyes with retinal detachment were immobilized by traction sutures under the inferior and medial rectus muscles in order to study the rate of "spontaneous" reattachment following such fixation. There was an almost complete reattachment in 45% of cases, and partial reattachment (at least half of the detached area) in 40%. Little or no reattachment was observed in 15% of cases. Reattachment of the retina prior to the operation is considered advantageous for the success of surgery.

Adolescent↗
PubMed1976

Hydrodynamic events in the vitreous space accompanying eye movements. Significance for the pathogenesis of retinal detachment.

The powers elicited in the vitreous body by eye movements have hardly been subjected to examinations, and the same goes for currents in the vitreous. Model experiments have demonstrated that intra-ocular currents are not elicited by translatory, but so much more by rotatory movements. Furthermore, it is demonstrated that a thin perforated membrane fitted on the inside of the wall of a glass cylinder filled with water, will detach, with rotatory movements. Even minimal rotational movements cause a flow through the hole. It is discussed whether these findings apply to the eye in vivo.

Adult↗
PubMed1975

Blood-brain barrier lesions in acute hypertension in rabbits after unilateral X-ray exposure of brain.

Acute hypertension was induced by metaraminol at different time intervals following irradiation in rabbits exposed to unilateral X-ray irradiation against the brain (3000 R) and in control animals. Hypertension resulted in a few areas of Evans blue extravasation in control animals. In the irradiated animals there was a marked increase in tracer extravasation on the half of the brain exposed to X-rays, indicating an increased vulnerability of cerebral vessels to blood pressure increase after irradiation.

Acute Disease↗