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Biomedical subjects

B Rockstroh

Publications and source records attributed to B Rockstroh.

At least 91 records · Page 5Linked to original sources

Principal component analysis of slow brain potentials during six second anticipation intervals.

The comparison of principal component analyses between seven experimental studies demonstrates a remarkable similarity of the extracted components. Slow scalp-recorded potentials of the brain (SPs) during a constant 6 sec foreperiod can be described by an early frontal, and a late preparatory component. Furthermore, an additional intermediate component may be retained by the PCA. This component seems to reduce the between-subject variance and often describes processes dependent on stimulus repetition. There is evidence favoring the varimaxed solution of the PCA for the parametrization of most of the experimental data.

Biofeedback, Psychology↗

The influence of low-level transcortical DC-currents on response speed in humans.

Low-level direct currents (DC) are thought to polarize brain tissue and to affect brain processes. The present experiments investigated the effects of low-level transcortical DC-currents on response speed and physiological variables in humans. The DC-currents were applied during the warning interval within a constant foreperiod reaction time paradigm. Currents of less than 0.3 mA were applied between a vertex electrode and a noncephalic reference. The polarity of the electrical source varied randomly across trials within subjects. The first two studies showed that subjects respond fastest when the positive pole is applied to the vertex. Under the same conditions higher skin conductance responses were observed as compared to vertex negative conditions. The dynamics of the observed responses suggest that the brain "learns" to respond differentially to the different current polarities. This was confirmed by the third study, which documented different conditioned electroencephalic responses subsequent to current application.

Cerebral Cortex↗

The influence of low-level, event-related DC-currents during time estimation in humans.

Two experiments were designed to investigate further the influence of low-level transcephalic DC currents on human reaction time and time perception. Thirty-two subjects participated in the experiments, with the second one a replication of the first. During a first trial series, subjects responded to the offset of a 6 second tone. Simultaneous to tone presentation a current was applied between vertex and collar bone electrodes. Current polarity varied randomly across trials. During a second trial series, subjects interrupted tone and current when they estimated a time interval of same length as the previously experienced had elapsed. In both studies subjects interrupted the tone/current after a shorter interval when the negative pole was applied as compared to vertex-positive trials. Results suggest that a vertex-negative external current suppresses an internally required state, whereas an external positive current supports internal SP-generation. The brain may tend to terminate the former state earlier than the latter.

Acoustic Stimulation↗

Biofeedback of slow cortical potentials. I.

An experiment was performed to investigate the self-regulation of slow cortical potentials (SCP) found in a previous study (Elbert et al. 1979). Seventeen subjects received continuous visual feedback of their actual cortical shift perceptible as a rocket moving across a TV-screen during intervals of 6 sec; subjects had to direct the rocket into one of two goals representing more or less cortical negativity, depending on the pitch of two signal tones. Within two identical experimental sessions feedback trials alternated with test trials without feedback. Highly significant differences of SCP between the two required polarities were demonstrated. The most pronounced differences were observed during test trials without feedback of the second session in which a positive shift below baseline level occurred when positivity (or less negativity) was required.

Adult↗

Biofeedback of slow cortical potentials. II. Analysis of single event-related slow potentials by time series analysis.

A single trial analysis of slow cortical potentials treating the EEG as a time series was developed. The method was applied to data resulting from an experiment on self-regulation of slow cortical potentials (SCP). Parametric models of the EEG were developed on the basis of autoregressive filter models and a two-component model of SCP (during 6 sec intervals), taking into account ocular influences as a further parameter. Results from different models were compared with each other and with results of averaging SCP data. For the present data time series analysis and traditional analysis provided qualitatively equal results, but fewer trials were necessary for analysis in the single trial approach and more detailed structures of the data became evident. If the EEG was filtered above 5 Hz it could be described by an autoregressive filter model of low order. Ocular influences were estimated as too small in a non-filtered EEG compared to the filtered EEG.

Biofeedback, Psychology↗

Conditional tonic stimulus control of nonspecific arousal.

Subjects performed a reaction time (RT) task in the presence of colored indirect lighting which had previously been associated with either sporadic electric shock (Unsafe context) or no shock (Safe context). Autonomic and cortical processes were influenced by the visual context in two ways. Nonspecific arousal was elevated in the Unsafe context as compared with the Safe context (larger SCR and more accelerative HR change elicited by the RT warning stimulus, and retarded habituation of the middle component of the slow cortical potential during the warning stimulus). In addition, information processing may have been impaired in the Unsafe as compared to the Safe context, since the earliest component of the SCR and the N100 component of the auditory evoked potential were both reduced. Higher frequency of unelicited SCR was observed following changes from a Safe to an Unsafe context than with reverse changes, during the association of these contexts with shock, but this was the only evidence of direct tonic conditioning. In general, the results demonstrate the degree to which psychophysiological processes may be influenced by tonic environmental conditions.

Adolescent↗

Area-specific self-regulation of slow cortical potentials on the sagittal midline and its effects on behavior.

Exteroceptive feedback was given for negative and positive shifts in slow potentials (SPs) recorded from Fz, Cz, or Pz (between groups design). Slow potentials at the feedback site were referred to adjacent scalp and non-cephalic electrodes, so as to confine SP shifts to the feedback location. Area-specific regulation of SPs was obtained at each midsagittal site after 3 days of feedback training. Subjects reported sensorimotor and emotional arousal when negative SP shifts were trained frontally, but not when negative shifts were trained parietally (cognitive/attentional strategies reported after parietal feedback). Area-specific regulation of SPs was subsequently abolished when behavioral tasks were added to further probe frontal/parietal differences (dual-task procedure). These findings indicate that area-specific self-regulation of SPs is possible on the sagittal midline, and that self-regulated parietal SPs (in contrast to frontal ones) arise from non-motoric generators. The source of SP self-regulation was more readily probed by verbal reports of feedback strategy than by study of dual-task relations, because feedback control was disrupted by the dual-task requirement.

Adult↗

Biofeedback produced slow brain potentials and task performance.

Twenty subjects learned to control slow potential (SP) shifts of the brain by means of a biofeedback procedure. Depending upon the pitch of a signal tone, negative SP shifts had to be increased or reduced during intervals of 6 sec each. Visual feedback of the actual SP shift was given. Blocks of training trials alternated with blocks of test trials without any feedback of the SPs. At the end of every test trial a simple arithmetic problem had to be solved by the subjects. Subjects performed the computation in a shorter time interval if an increased negativity preceded task onset as compared to slower response times during suppression of negativity. Results suggest that cortical negativity reflects unspecific preparation for cerebral performance.

Attention↗