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Biomedical subjects

B Remington

Publications and source records attributed to B Remington.

At least 19 recordsLinked to original sources

Anomalous elastic response of silicon to uniaxial shock compression on nanosecond time scales.

We have used x-ray diffraction with subnanosecond temporal resolution to measure the lattice parameters of orthogonal planes in shock compressed single crystals of silicon (Si) and copper (Cu). Despite uniaxial compression along the (400) direction of Si reducing the lattice spacing by nearly 11%, no observable changes occur in planes with normals orthogonal to the shock propagation direction. In contrast, shocked Cu shows prompt hydrostaticlike compression. These results are consistent with simple estimates of plastic strain rates based on dislocation velocity data.

Journal Article↗

The application of moxidectin formulations for control of the cattle tick (Boophilus microplus) under Queensland field conditions.

OBJECTIVE: To assess the control of the cattle tick (Boophilus microplus) and the performance of commercial cattle treated with the macrocylic lactone endectocide, moxidectin, formulated either as an injection or as a pour-on. DESIGN: Groups of 10-12 tick infested cattle were treated with moxidectin injection, moxidectin pour-on or remained untreated (28-day trials) or were treated with deltamethrin-ethion as a dip (140-day trials). The cattle were exposed to natural tick challenge under field conditions. PROCEDURE: Tick numbers on trial cattle were recorded in each trial before the initial treatment and in the 28-day trials at 7, 14, 21 and 28 days or in the 140-day trials, at 28-day intervals before each of the treatments and at the final inspection. Body weights of the cattle were also recorded prior to the initial treatment and at the termination of each trial. Cattle were observed on the day of each treatment and at each inspection for evidence of any reactions to treatment. RESULTS: 28-day trials: Significant reductions in tick counts were recorded in both treatment groups when compared with cattle in the untreated group. Weight advantage was recorded in the moxidectin treated groups. 140-day trials: All three treatments resulted in zero or low tick counts at each inspection with the exception of the pour-on treatment at week 8 in one trial and week 9 in the other trial. Additional weight gain was recorded for both the moxidectin treated groups, relative to the deltamethrin-ethion dip groups, but was significant only for the pour-on groups. There was no evidence of any local or systemic adverse reaction in any treated cattle in any trial. CONCLUSION: Good to excellent control of the cattle tick (Boophilus microplus) was demonstrated with the moxidectin formulations in all trials, the injection being particularly effective. An improved performance was recorded in all trials in cattle treated with both moxidectin formulations when compared with the untreated cattle and with cattle treated with the deltamethrin-ethion dip. There was no evidence of any local or systemic adverse reaction to treatment with either moxidectin formulation.

Administration, Topical↗

Naming, the formation of stimulus classes, and applied behavior analysis.

The methods used in Sidman's original studies on equivalence classes provide a framework for analyzing functional verbal behavior. Sidman and others have shown how teaching receptive, name-referent matching may produce rudimentary oral reading and word comprehension skills. Eikeseth and Smith (1992) have extended these findings by showing that children with autism may acquire equivalence classes after learning to supply a common oral name to each stimulus in a potential class. A stimulus class analysis suggests ways to examine (a) the problem of programming generalization from teaching situations to other environments, (b) the expansion of the repertoires that occur in those settings, and (c) the use of naming to facilitate these forms of generalization. Such research will help to clarify and extend Horne and Lowe's recent (1996) account of the role of verbal behavior in the formation of stimulus classes.

Attention↗

Experienced and inexperienced health care workers' beliefs about challenging behaviours.

Within a behavioural framework, staff responses to challenging behaviours have been identified as likely to ensure the long-term maintenance of such behaviour. However, little has been done to understand why staff behave as they do. The present paper hypothesized that staff's beliefs about the causes of challenging behaviours may be an important factor in determining staff responses to it. Beliefs about causes of three topographies of challenging behaviour (self-injury, stereotypy and aggression) were elicited from 148 experienced and 98 inexperienced institutional staff and nursing students using a questionnaire measure. Results showed that experienced participants held beliefs that were more consistent with contemporary theories of challenging behaviours than inexperienced participants. Experienced participants also distinguished between the behaviours in terms of their causes. These data were interpreted as reflecting a 'needs-based' rather than a 'functional' approach to intervention for challenging behaviours. Implications for staff training, community living and future research on staff behaviour were briefly considered.

Adult↗

Adults' responses to self-injurious behavior. An experimental analysis using a computer-simulation paradigm.

The behavior of staff who care for people with mental retardation has been identified as a significant factor in the development and maintenance of challenging behaviors. In a recent analysis, Hastings and Remington (1994a) suggested that both environmental contingencies and rules from other people may affect staff actions. The present study tested this analysis by asking participants to respond to a computer simulation of a work situation involving the care of two individuals who engaged in self-injurious behavior. Fifty participants "interacted" with an attention-seeker and a social-avoider on a simulated teaching task. Results showed that rules were the main factor governing performance. The aversive nature of the contingencies between the self-injury and participants' "attending" behavior also appeared to be influential. The implications of these results for work with care staff, the analysis of challenging behaviors, and experimental research on rule-governed behavior are discussed.

Adolescent↗

Alcohol as an unconditioned stimulus in human classical conditioning.

Recent experiments with human subjects have shown that drug cues (e.g. sight of beer or needle and syringe) elicit different responses than do neutral stimuli. However, because conditioning has not been carried out in the majority of cases, it is not clear why drug cues have different response eliciting capacities; associative and nonassociative mechanisms may both play a part. In this experiment a counterbalanced differential conditioning procedure was used to isolate the role of associative processes in the development of physiological, behavioural, and subjective conditioned responses to cues for alcohol over the course of repeated conditioning sessions. Twelve healthy volunteers took part in the experiment which involved each subject attending for ten sessions. On physiological measures evidence was found for conditioning of skin conductance and cardiac inter-beat interval responses to cues for alcohol delivery. Over the course of conditioning on behavioural measures of drink consumption there were changes in the rate of consumption and number of sips taken as a function of whether or not the drinks contained alcohol. Finally, on subjective measures, there was a differential change in subjective state in response to alcohol and soft drink expectancy as conditioning progressed.

Adult↗

Staff behaviour and its implications for people with learning disabilities and challenging behaviours.

Many people with learning disabilities engage in challenging behaviours which, behaviour analytic models suggest, are social behaviours sensitive to the actions of others in the environment. In this paper, the research literature on the behaviour of staff, especially that pertaining to interactions with people with challenging behaviours, is reviewed. Empirical evidence is found to support the hypothesis that staff actions affect clients' challenging behaviours. In addition, studies of staff behaviour show that their behaviour is often counter-habilitative. Firstly, staff spend little time interacting with clients and the quality of these interactions is often poor. Secondly, observational studies have shown that staff respond intermittently to challenging behaviours, and self-report studies indicate that many of these responses are of a nature that may reinforce such behaviours. Finally, although limited, evidence suggests that behavioural programmes for clients with challenging behaviours are rare and where they do exist they are often not carried out by staff. To date, interventions for staff behaviour (training and management approaches) have acted to change these ways of behaving but have not been founded on adequate analyses of staff action. A call is made for analyses of staff behaviour, and other implications for research and practical work with staff are discussed.

Humans↗

An analysis of labels for people with learning disabilities.

There have been many changes in the terminology used to describe people with learning disabilities in recent years. One of the arguments for 'new' terms is their more positive connotations. This claim was investigated in a study in which sixth-form pupils (age 16-19) completed semantic differentials for contemporary and older labels referring to learning disabilities. Apart from the label 'exceptional', all had very similar negative connotations. The problems arising from using denotative terms inaccurately in order to foster more positive images of individuals with learning disabilities are briefly discussed. Alternative ways of deciding between labels are suggested.

Adolescent↗

Different drink cues elicit different physiological responses in non-dependent drinkers.

Different kinds of physiological response to stimuli which have been associated with alcohol ingestion have been observed in human subjects. A literature review shows that when subjects are exposed to alcohol associated stimuli without consuming the drinks then increases in arousal, as indexed by skin conductance and heart rate increases, tend to occur. If subjects consume drinks which have been associated with alcohol ingestion, then decreases in arousal tend to occur. Forty non-dependent drinkers were asked to either consume or hold drinks which either had a history of alcohol association or did not. Interactions were observed between the activities subjects engaged in with the drinks and the degree of alcohol association of the drinks. Presentation of alcohol associated drinks produced smaller increases in arousal than non-alcohol associated drinks if the drinks were consumed but vice versa if the drinks were just held. The results support the conclusions drawn from the literature review and have implications for current theories of conditioned responses to drug cues and the related theories of the motivational processes involved in the regulation of drug intake.

Adult↗

A method for producing alcohol placebos.

A method for producing placebo drinks that are hard to discriminate from alcoholic drinks is described. Subjects received a series of paired comparisons, each involving a distinctively flavoured alcoholic drink and one of six different placebo versions of it. Following each such comparison, rating scales were used to record the 'alcoholic strength' and 'sensory intensity' of a placebo drink relative to the alcoholic drink. The procedure was replicated using another distinctive alcoholic drink and another set of placebos. Based upon a multivariate analysis of subjects' ratings, the version of the placebo that was most difficult to discriminate from it's corresponding alcoholic drink was identified for both alcoholic drinks. The method is intended to be a general one for producing placebo versions of alcoholic drinks which do not differ on any dimensions which can be shown to be important in producing a response.

Adult↗

The role of referential speech in sign learning by mentally retarded children: a comparison of total communication and sign-alone training.

We conducted two experiments to assess the role of referential speech during sign training in which the spoken words corresponding to signs were receptively known to the participants. An alternating treatments design was used to compare sign acquisition across two teaching conditions in which referents were presented either with or without the corresponding verbal label. During the first experiment, signs were taught concurrently; during the second experiment, signs within each of the respective conditions were taught in a serial fashion. In both experiments, signs taught by total communication were acquired faster than those taught by sign-alone training.

Child↗