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Biomedical subjects

B Radojicić

Publications and source records attributed to B Radojicić.

At least 19 recordsLinked to original sources

[Lumbar spine fractures].

In Special Hospital for orthopaedy, neurosurgery and neurology "Vaso Cuković" in Risan, during last 30 months, 51 patients with lumbar spinal fractures were treated. Surgical intervention was performed in 12% of the patients while 88% of them were treated by postural reduction. In the moment of arrival, neurological deficit was noticed in ten patients, and after the treatment three of them had a significant improvement of the function. During the treatment we had one exitus as a consequence of the polytrauma. The authors analyse the results of the treatment favorising early mobilisation in compressive lumbar spinal fractures and surgical intervention in the patients with neurological deficit.

Female↗

[Prednisone therapy in patients with pernicious anemia (report of 2 cases)].

The effects of Prednisone therapy at two patients with pernicious anemia were studied on haematologic response, gastric secretion and gastric mucosal hystology. The treatment resulted in each case in correctin of the megaloblastic to normoblastic erythropoesis, and increse in reticulocytes, hemoglobin level and red cell count. Schilling-s test was normalised in one case that means that Prednison enchanced B12 absorption. Gastric secretion of acid and gastric hystology were not respond during the Prednisone therapy. It was discused about immunological problems in pernicious anemia which are very important and required continued investigations.

Anemia, Pernicious↗

Chromosome changes in patients treated with "Myleran".

The aim of this study is the determination of chromosomal changes in patients suffering from chronic leucosis, after therapy with the cytostatic "Myleran", to find out whether this cytostatic causes them, because of clinical experience which indicates its value in the treatment of chronic myeloid leukemia. Patients were treated with therapeutic doses of 4 mg per os daily. Analysis with present methods in patients receiving relatively small total doses did not discover the other visible chromosomal aberrations in leucocytes in peripheral blood, except the usual aberrations caused by chronic leucosis.

Busulfan↗

[Case of implantation of human fetal thymus on the immunological reactivity in patients with Hodgkin's disease].

Five patients with Hodgkin's disease (IV stage) were implanted with fetal human thymus. Implantation were performed under the fascia of rectus abdominis muscle. Thymuses were obtained from fetuses 4-5 month old in aseptic condition and stored in tissue culture medium 199, before implantation. Immunological studies carried out during 4-6 months, revealed the elevation of the number of the lymphocyte in the peripheral blood, normalization of the number of rosete forming cells (RFC) as well as the response of peripheral blood lymphocytes to phytohaemagglutinin (PHA) stimulation. Two patients had long improvement of immunological responsiveness, but the other 3 only a transitient one during the first month after implantation. The possibility of the immunologic treatment in the early stages of Hodgkin's disease is discussed.

Adolescent↗