Actinomycosis revisited--pelvic actinomycosis associated with the intrauterine device.
Explore the source record for details and available documents.
Biomedical subjects
Publications and source records attributed to B R King.
Explore the source record for details and available documents.
In contrast to the reported response of inbred male mice [Beeker et al. (2)], young male rats with differing preferences for ethanol (P and NP lines) exhibited no significant change in brain cyclic AMP-binding activity following free-choice consumption of ethanol for 28 days. However, for the NP line, phosphorylation of the kinase regulatory subunit (RII) by basal kinase activity in the cytoplasmic fraction was significantly suppressed by free-choice ethanol consumption but the preferring (P) line showed no such changes. Thus the changes in phosphorylating activity appeared to be associated with differences in the animals' responses to ethanol exposure. The lower preference line (NP) consumed a smaller amount of ethanol (mean = 1.7 +/- 0.1 g/kg/24 hours) and showed a significant decrease in phosphorylating activity relative to vehicle-treated animals whereas the high preference line (P) showed no such change in kinase catalytic activity relative to controls, even though these animals consumed a significantly larger dose of ethanol (mean = 5.9 +/- 0.7 g/kg/24 hours). The data suggest that the P and NP lines differ as to their sensitivity to ethanol-induced changes in the phosphorylation of brain protein kinase regulatory subunit, an important parameter in the overall regulation of kinase activity.
INTRODUCTION: Prehospital (EMS) personnel routinely enter patient's homes and often are the first trained persons to evaluate an ill or injured child. Therefore, it is vital for these individuals to recognize child abuse (CA), and to understand the proper procedures for reporting suspected cases. METHODS: A questionnaire was administered to prehospital care-givers participating in a seminar on pediatric emergencies. Questions were designed to test factual knowledge of CA and the correct reporting procedures, as well as to evaluate attitudes toward CA. RESULTS: There were 48 responses to the questionnaire; 34 (71%) were paramedics, the remainder were emergency medical technicians (EMTs) and/or registered nurses (RNs). Thirty-three (69%) practiced either in a rural or suburban setting. Subjects had an average of 10.8 years of prehospital emergency-care experience. Twenty-eight (58%) reported no previous training in CA. All participants understood the nature of CA, were able to identify the various forms of CA, and believed CA to be a significant problem. However, 33 (69%) did not understand the legislation that mandates reporter status, and while 27 (56%) claimed to have reported CA, only 16 (33%) had made a report either to police or to children's services workers. Of the 21 who never had reported a case of CA, 14 (67%) believed that they never had encountered an abused child. The remainder were not certain, and therefore, did not report, or thought that the hospital staff would report. CONCLUSIONS: While this subject deserves further study, it seems that many EMTs and paramedics lack a complete understanding of their role in the identification and reporting of CA. This information should be emphasized further in EMT and paramedic education, and should be reinforced through continuing education.
INTRODUCTION: Many colleges and universities appear to exist in relative isolation from community-based emergency medical services (EMS) systems. In response, some have developed their own EMS systems. OBJECTIVE: To determine the extent of this phenomenon and to delineate the characteristics of these systems. DESIGN/METHODS: Questionnaires were mailed to 1,503 colleges/universities in the United States and Canada. The questionnaire asked whether the institution had an EMS system and included 19 questions about the characteristics of the system. RESULTS: A total of 919 (61%) responses were received. Of the institutions responding, 234 (25%) had an EMS system and 31 (3.4%) were considering starting a system. Characteristics of the systems were as follows: 1) Types of patients-the two most common call types were medical and trauma/surgical; 134 (57%) reported one-fourth of calls to be medical and 91 (39%) reported one-fourth of calls to be trauma/surgical. 2) Type of service-133 (57%) services transport patients; 195 (83%) respond only to the campus or other university property; the remainder also respond to the community; and 135 (58%) function all year. 3) Dispatch-178 (76%) are dispatched by the campus police, although most services are dispatched by several sources; 46 (20%) use 9-1-1. 4) Personnel-two systems (0.85%) exclusively employ paramedics; 141 systems (60%) have at least one emergency medical technician; the remainder use emergency care attendants and first-aid providers; 118 (50%) have medical directors, of these 76 (64%) are student health physicians and 21 (18%) are community physicians. 5) Demographic Information-The majority of the campus-based EMS systems exist on small campuses in urban areas. CONCLUSIONS: A significant number of colleges/universities have EMS systems and one-half transport patients. However, the level of training of the personnel and medical direction may be below the standard for the EMS systems in the communities in which these campus-based systems exist.