Early cardiac anaesthesia at Green Lane Hospital.
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Biomedical subjects
Publications and source records attributed to B R Hutchinson.
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Volume and pH of gastric contents were measured after anaesthetic induction in 99 in-patients undergoing general and vascular surgery scheduled for either morning (50) or afternoon (49) lists. Significantly fewer patients in the morning group had pH values below 2.5. The mean pH value of the morning group was significantly higher than that of the afternoon group. There was a positive correlation between duration of fast and pH (the longer the more alkaline) for the groups combined. No significant relationship could be shown for any factor with volume.
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Three groups, each of forty children aged less than five years and prepared for elective surgery, had their gastric contents' volume and pH measured. The control group showed an incidence of 67-5 per cent with high acidity (pH equal to or less than 2-5). In the second and third groups magnesium trisilicate mixture was given within thirty minutes prior to induction of anaesthesia. The second group, sampled after induction of anaesthesia, showed a marked reduction in acidity, while the third group, sampled at the termination of anaesthesia and surgery, demonstrated that in most cases the neutralization of gastric acidity was still effective.
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The incidence of Mendelson's syndrome in the four major Auckland hospitals is reviewed. The frequency of this condition was reduced following the pre-operative administration of magnesium trisilicate mixture in two hospitals. A trial was conducted in a third hospital and this showed that a 52 per cent incidence of highly acid gastric juice (pH less than 2.5) in patients prepared for elective surgery was reduced by administration of magnesium trisilicate mixture at the time of premedication. When the magnesium trisilicate mixture was given within the 30 minutes prior to induction of anaesthesia, the number of patients with highly acid gastric content fell to one per cent.
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