Search PubMed⌕ Search

Biomedical subjects

B Petrov

Publications and source records attributed to B Petrov.

16 recordsLinked to original sources

[Post-cystectomy derivations - a rule or control of technical skills?].

Limitations in gaining better understanding of bladder tumor responsiveness do exist, and accordingly the therapeutic interventions undertaken in diverse forms of the disease are conspicuous for discrepancies (M. J. Droller, 1990). E. Bricker in 1950 is the first to practically implement ileal conduit for urine derivation, and thus initiates the new and newest continent derivations. Over the period 1992-1998, in the Chair of Urology are performed 76 cystectomies with different urine derivations, using seven methods for the purpose: [table: see text] Also discussed are the conditions a derivation should mandatorily meet. Emphasis is laid on the fact that the choice of derivation is still largely dependent on the skill and experience of urologists.

Adult↗

Optimization of a high-performance liquid chromatographic method for the determination of nucleosides and their catabolites. Application to cat and rabbit heart perfusates.

A high-performance liquid chromatographic method is described for the separation of nucleosides and related compounds in a single isocratic run. The separation of a standard mixture of at least thirteen compounds is achieved within 15 min on a new type of reversed-phase column 25 cm long, filled with 5-micron particles of Select B. Pre-treatment of the silica particles before silanization has given this type of reversed-phase material unique characteristics for basic and acidic compounds. Chromatograms are shown to compare the effectiveness of the Select B column for the separation of nucleosides with that of other C18 and C8 phases. The separation is achieved with 0.3 M ammonium dihydrogen phosphate (pH 4.00) and a mixture of methanol, acetonitrile and tetrahydrofuran. Detection is carried out with a variable-wavelength UV detector at 254 nm. Sample preparation and the influence of the organic solvents, pH and buffer concentration are described. To illustrate the applicability of the method, representative chromatograms are shown of perfusates of Langendorff preparations and the working hearts of cats and rabbits. Remarkable differences were obtained before and after ischaemia and before and after treatment with a nucleoside transport inhibitor. Baseline separation of cytosine, orotic acid, cytidine, uracil, uric acid, hypoxanthine, xanthine, inosine, guanosine, xanthosine, allopurinol, thymine and adenosine was achieved. The detection limit for these compounds was less than 1 ng per injection.

Animals↗

[Not Available].

Explore the source record for details and available documents.

History, Modern 1601-↗

[Rhabdomyosarcomas in the field of otorhinolaryngology].

The authors describe rabdomyosarcoma of different location in two patients of different age. One patient, 51 years old, had rabdomyosarcoma located in the larynx. Its detection was late because its late manifestation. The patient refused the suggested treatment and the issue was lethal within the first year after the first symptoms had been discovered. The second patient was a child, aged 5, with rabdomyosarcoma on the upper lip. The tumour was detected relatively early and it was cured (operatively, by radiation and chemio-therapy). Unfortunately the result was lethal two years after the beginning of the illness.

Child, Preschool↗