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Biomedical subjects

B Pertuiset

Publications and source records attributed to B Pertuiset.

At least 73 records · Page 4Linked to original sources

[Neuropathological study of adult intracranial hemorrhage. General data in 500 cases].

The systematic pathological study of 500 patients with intracranial hemorrhages (ICH) [341 (68 P. 100) CEREBRAL HEMORRHAGES (C.H.); 119 (24 p. 100) meningeal hemorrhages (M.H.); 39 (7,8 p. 100) subdural hematomas (S.H.) and, at last, one extradural hematoma] has been practiced. Those cases were issued primarily from neurological and, at a lesser degree, from neurosurgical departments. Etiological data, complications, associated findings and causes of death have been analysed. High blood pressure is the main etiological factor in C.H. This is confirmed by the statistical comparison between the incidence of this factor in our material and in the whole French population. However, nearly 50 p. 100 of ICH occuring in normotensive patients are C.H. The incidence of cirrhosis is much higher in our study than in other reports from the literature. The frequently associated high blood pressure does not seem to enhance the incidence of CH in patients with liver cirrhosis. Although this last factor can be found alone, its real etiological importance in CH cannot be assessed on account of the lack of data concerning the incidence of liver cirrhosis in the French population. The incidence of anticoagulant therapy is high in S.H. On the contrary, this factor does not seem to enhance the risk of high blood pressure induced C.H. The traumatic etiology of S.H. is significantly higher than the anticoagulant therapy etiology which, however, is very high in our study.

Adult↗

[Chronology of diagnostic and therapeutic activities in the 3 weeks following rupture of an intracranial saccular aneurysm (series of 316 cases)].

The authors advocate to operate grades I, II and III patients on the 6th or 7th day following the onset of SAH, that is to say between the "oedema" period and the rebleeding period. They study all investigations and therapy which are necessary previously to the operation and advocate to perform a CT scan as the first investigation as well as to control the intraventricular pressure. Their opinion is based on the study of 316 cases admitted over a period of 5 years 218 have been operated upon by a team of 7 neurosurgeons with an overall mortality of 18.3 p. 100. The mortality in grade I and II patients has been 13.3 p. 100. This percentage includes all fatalities occuring in the six months following surgery. The senior author assumes that a good audio-visual teaching of the trainees can improve the results.

Aged↗

[The treatment of trigeminal neuralgia by retro-gasserian differential electro-diathermy. One hundred cases (author's transl)].

Controlled thermocoagulation of Gasserian ganglion has been used in 100 patients presenting trigeminal neuralgia. Facial pain disappeared immediately in all cases, except four where it persisted at a minor degree during few days. Post-operative deficits are quite minimal and consist of hypoalgesia more or less marked; numbness to touch has never been observed except in a limited area in 12 patients. There have been no corneal problems. Paresthesias were noted immediately in 10 patients; they disappeared gradually and were troublesome only in four. The rate of recurrence (with a mean post-operative survey of 11 months is 13%). This technique of controlled thermocoagulation re presents the safest way of treating trigeminal neuralgia when it is uncontrollable with drugs.

Adolescent↗

Delineation of pituitary adenomas by angiotomography.

The supra sellar extension of even small sized pituitary adenomas can be delineated with accuracy by angiotomography. This technique avoids the discomfort of pneumoencephalography in many patients. Angiotomography is also useful for the differential diagnosis of empty sellae.

Adenoma↗

Diagnosis of pinealoblastomas by positive response to cobalt-therapy.

Surgical excision of pineoblastomas is considered dangerous, and relief of raised intracranial pressure by shunting followed by cobalt therapy is the preferred treatment. Demonstration by pneumoencephalography of tumour shrinkage after therapy confirms the diagnosis of pineoblastoma. Failure of the tumour to become smaller indicates a different pathology which calls for a surgical approach, except in the case of a brain stem tumour.

Adolescent↗

Temporary external valve drainage in hydrocephalus with increased ventricular fluid pressure. (Experiences with 202 cases). (Experiences with 202 cases).

When the ventricular fluid pressure has reached a level of 120 to 150 mm H2O, there is a risk of rapid internal herniation. The effects of corticoids and hyperosmolar drugs on this are not as striking as they are on brain oedema. The only efficient therapy is the establishment of an external ventricular drainage system proposed for the first time in 1941 by Ingraham and Campbell and regulated with a valve system by White et al. 1967. From our experience of 202 cases we review the technique, the indications, and the complications of ED.

Brain Neoplasms↗

[Total removal through the ventricle in 2 cases of pallidocaudal arteriovenous abnormalities under deep hypotension].

Two cases of A.V.M. situated in the pallido-caudal area and directly nourrished by the anterior perforated space arteries have been investigated using three angiographic techniques: selective internal carotid angiography, angiotomography including pneumoencephalography and angiography under deep hypotension at 30 mm Hg (mean pressure) induced by sodium nitroprusside. These investigations led to the conclusion that the A.V.M. could be removed through the lateral ventricle. Both were radically removed using the retrograde technique under deep hypotension and the operative microscope. Both patients are alive without additional neurological deficit.

Adult↗

[Chronic functional dislocation of the cervical spine with radiculo-spinal effects. Discectomy by anterior route and fusion without graft].

X ray dynamic study of cerevical spine movements in 12 patients with neurological impairment has shown an abnormal mobility between two vertebrae in the anterior or posterior direction. This abnormal mobility which has been called functional dislocation, is situated usually over major discarthrosic lesions rather than under. This dislocation, which appears during voluntary and automatic movements of the head and neck has been qualified chronic. A discectomie through an anterior surgical approach and a bony fusion of vertebral bodies without any graft at the dislocation site lead to 10 good results. 2 failures have been imputed to the fact that there was a 10 years evolution of a tetraplegia before operation. The pathogenesis of chronic functional dislocation of the cervical spine is discussed with regard to compression and stretching of the spinal cord, roots and arteries of both. Traumatism of vertebral arteries during dislocation remain under discussion.

Cervical Vertebrae↗

[Variations in local cerebral blood volume depending on the mean arterial blood pressure in man].

A radio isotopic technique is described to measure and monitor the cerebral blood volume during a controlled arterial hypotension induced by sodium nitroprusside in anesthetised patients (neurolepanalgesia) submited to surgery for a ruptured saccular aneurysm. The study was made in 10 cases from 90 mm Hg to 30 mm Hg mean blood pressure monitored from a transducer connected to an intra humeral microcatheter. The figures obtained show an increase of the cerebral blood volume from 90 mm Hg to 50 mm Hg in every patient and a linear correlation when the pressure is lowered under 50 mm Hg level; therefore under a mean arterial pressure of 50 mm Hg the autoregulation arterial mechanism is out of work.

Blood Pressure↗

Demonstration of cystic brain tumors by angiotomography.

Cysts in cerebral tumours, as small as 1 cm in diameter, have been demonstrated by angiotomography with the sections made in the frontal plane. Two signs suggest a cystic lesion; a geometrically round, vessel-like outline in either the arterial or venous phase, resulting from a cystic cavity under pressure, and, during the parenchymatous phase, a radiolucent area having a radiological contrast identical to the non-injected hemisphere.

Brain Neoplasms↗