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Biomedical subjects

B Peitersen

Publications and source records attributed to B Peitersen.

At least 37 records · Page 2Linked to original sources
PubMed1994

[HIV antibody positive children in Denmark].

The AIDS-committee of The Danish Society of Paediatrics has done a nation-wide study among infants and children under the age of 15 with AIDS or HIV-antibodies in preparation for planning prevention and treatment. Clinical data have been collected from the Departments of Paediatrics and Infectious Diseases, Haemophilia, Dermatology and Internal Medicine up to 1 March 1993. The study includes 44 infants with a risk of vertical transmission from the mother and 16 children with haemophilia. No cases were found to be infected by blood-transfusion. Twenty of the 44 infants with congenital HIV-antibodies were HIV-infected. Seven of them died from AIDS, 10 currently have AIDS and three are asymptomatic. Seventeen infants are well and HIV-antibody negative after the age of 18 months. Seven infants still have unclarified status, but all are well. Three of the patients with haemophilia are dead. The 13 others do not have AIDS. It is surprising that most of the infected infants' mothers were not known to be infected before the infants got sick. Thus infected infants exist in families who are not suspected to be HIV-infected. The AIDS-committee of The Danish Society of Paediatrics has proposed recommendations for HIV-testing of infants and children. HIV-infected families need comprehensive psychosocial care. The risk-factor from blood-transfusion is now eliminated, but vertical transmission will continue to be a risk-factor. The size of the problem in Denmark will not be known until an epidemiological study of pregnant women has been conducted.

Acquired Immunodeficiency Syndrome↗
PubMed1994

[Morbidity, mortality and late sequelae in extremely premature infants born in the Hvidovre Hospital, 1985-1991].

In the period 1985 to 1991, 80 infants with gestational age below 28 completed weeks were born at Hvidovre Hospital, Copenhagen and transferred to the neonatal intensive care unit of the hospital. The incidence of extreme prematurity was 3.6 0/00. Twenty-eight infants died during the neonatal period (35%) and nine infants died later in infancy (11.3%). Forty-three infants (54%) survived. Forty four percent of surviving infants had one or more sequelae related to their prematurity or neonatal complications, mainly blindness or reduced vision, cerebral palsy and mental retardation. Neither gender, mode of delivery or birth asphyxia were important for survival and sequels. Neonatal complications such as patent ductus arteriosus, septicaemia, necrotizing enterocolitis, pneumothorax and cerebral haemorrhages were significantly related to survival and sequelae.

Birth Weight↗
PubMed1994

Retinopathy of prematurity: review of a seven-year period in a Danish neonatal intensive care unit.

In the period 1985-1991, 21,675 infants were born at the University Hospital of Copenhagen, Hvidovre Hospital, Denmark. Two hundred and twenty-four infants (10.3%) with birth weights < or = 1500 g and gestational ages < or = 32 completed weeks were transferred to the neonatal intensive care unit of the hospital. One hundred and eighty survived to at least 8 weeks of age and 170 had eye examinations. Forty-five of the 170 infants examined (26.5%) had retinopathy of prematurity (ROP) and 18 (40%) of these developed blindness or severely impaired vision, a higher incidence than reported in other studies. Significant differences were found between infants with and without ROP for: birth weight, gestational age, Apgar score at 1 min, resuscitation, ventilator treatment, duration of supplementary oxygen, severe complications in the neonatal period and sequels from the central nervous system. Statistical analysis, corrected for correlations, showed that the occurrence of ROP was related significantly to early intubation, hypotension, persistent ductus arteriosus and necrotizing enterocolitis.

Apgar Score↗
PubMed1993

[Survival in relation to gestational age in delivery before 32 complete weeks of pregnancy with low birth weights, 1,500 g or under].

In a retrospective study, all deliveries at Hvidovre Hospital, Copenhagen, with birth weights < or = 1500 g and gestational ages of 23 to 32 completed weeks were examined to find out how they were recorded and the survival of the baby. Sixty-one were registered as abortions, 151 as births. Sixteen infants (10.2%) were registered as stillborn and 9 (6.7%) were live born without major malformations but died in the delivery ward without transfer to the neonatal intensive care unit (NICU) of the hospital. The survival for infants without severe malformations was 72.4% for all liveborn infants, and 77.6% for infants transferred to the NICU. The youngest surviving infant was born after 24 completed weeks of gestation. Because of different criteria for selection, comparison between different studies is difficult. This investigation shows that registration of very premature deliveries can be heterogenous. This is of great importance for survival and outcome rates because of the small number of very premature infants. We suggest a registration of all deliveries taking place after 22 completed weeks of gestation including birth weight, gestational age, pulse, respiratory movements, lethal malformations and time of death to ensure a better knowledge of the prognosis of these tiny infants.

Congenital Abnormalities↗
PubMed1993

Retinopathy of prematurity in a Danish neonatal intensive care unit, 1985-1991.

During the 7 year period 1985 to 1991, 170 infants born in Hvidovre Hospital, Denmark, with birthweight < or = 1500 g and gestational age < or = 32 completed weeks survived at least 8 weeks or more and had eye examinations carried out. Forty-five infants had ophthalmoscopic evidence of retinopathy of prematurity (ROP). Eighteen developed blindness or severely reduced vision and 6 developed unilateral blindness. In 21 the ROP changes regressed. Eight infants eventually developed severe myopia. The 45 infants with ROP were compared with the 125 without ROP. There was no difference in birth weight, gender, or mode of delivery. Significant difference was found in gestational age, asphyxia, intensive treatment and complications. Particularly infants with ROP born with gestational age 27 to 29 weeks needed prolonged and more intensive treatment than infants without ROP. Infants with ROP had more frequently long term sequels from the central nervous system than infants without ROP.

Blindness↗
PubMed1992

[Congenital tuberculosis. 2 case reports].

Two cases of congenital tuberculosis are presented and the literature is reviewed. One child survived without sequelae while the other survived but was severely handicapped. The importance of early diagnosis and treatment of this rare but serious manifestation of tuberculosis is emphasized.

Child, Preschool↗
PubMed1991

Nasal airway resistance in the newborn.

The present study aimed to provide normative data for nasal airway resistance in the newborn. Anterior rhinomanometry was performed on 17 full term Caucasian infants aged 1 to 4 days, birthweight 3100 to 4150 g. No sedation or decongestion was performed. Average unilateral nasal resistance was 4.86 kPa/l/s (SD = 2.41) at a pressure threshold of 75 Pa. Average nasal resistance calculated from the right and left side recordings was 2.14 kPa/l/s (SD = 0.77). This corresponds to 21.8 cm H2O/l/s (SD = 7.9). The nasal resistance of the newborn thus is approximately 10 times that of the adult.

Airway Resistance↗
PubMed1986

Caliper skinfold measurements in newborns: analysis of a method.

Bilateral skinfold measurements on 10 different sites were performed blindly by 3 investigators in 118 newborns with a mean birth weight from 1,700 to 4,200 g. The caliper method was precise as judged by intra- and interobserver variances. Precision was independent of skinfold thickness, and not related to amount of training. Bilateral measurements of skinfolds over the quadriceps, pectoral and biceps muscles carried the highest precision. Precision was significantly increased by combination of these 3 measurements. There was no significant difference between the precision of these 3 bilateral measurements and 5 selected unilateral sites. For clinical practice, we recommend cumulated measurements of right-sided skinfolds over the quadriceps, pectoral, biceps and triceps muscles and subscapular skinfold.

Female↗
PubMed1986

Vestibular toxicity following netilmicin therapy in the neonatal period.

Thirty-seven children treated with netilmicin during the neonatal period were seen at follow-up at the age of 2-4 years to investigate for possible vestibular damage caused by netilmicin therapy. No definite vestibular damage could be found in these 37 patients, including three patients in whom greatly elevated serum concentrations of netilmicin had been measured. The present study confirms previous findings in adults showing a low ototoxicity of netilmicin.

Female↗
PubMed1980

Treatment of girls with excessive height prediction. Follow-up of forty girls treated with intramuscular estradiol and progesterone.

In a follow-up study of 40 tall girls treated with intramuscular estradiol and progesterone, the final height, bone age maturation, side effects and acceptance of treatment were evaluated. The mean duration of treatment was 18 months. During treatment, mean height increase was 6.5 cm (height velocity 3.7 cm/year), which is nearly 50% reduction of normal growth rate. The mean increase in bone age was 2.7 years (bone age velocity 1.8 years/year), which approximates twice the normal maturation rate. The mean reduction in final height was 5.0 cm as evaluated by the method of Bayley. Pinneau (BP), 2.9 cm by the method of Tanner et al. (TW) and 3.0 cm by the method of Roche et al. (RWT). The reduction was greatest when treatment was started before menarche, according to all three prediction methods. When treatment was started after menarch the calculated height reduction was greatest according to the BP method. There was good agreement between the three prediction methods in girls with a bone age below 12 years before treatment. In girls with a bone age above 12 years the height reduction by the BP method was much greater than when measured by the other methods. Side effects evaluated at follow-up were minimal and first menstruation occurred within 3 months (mean) after cessation of treatment. The number of pregnancies was estimated to be normal for age. All but three accepted the treatment. It is concluded that this type of treatment must be restricted to girls with severe psychological problems due to excessive height prognosis and selection for treatment must be based on an individualized evaluation.

Adolescent↗