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Biomedical subjects

B Page

Publications and source records attributed to B Page.

At least 91 records · Page 5Linked to original sources
PubMed1992

[Aseptic osteonecrosis of the knee induced by corticoids. MRI aspects].

Authors report the results of a series of 29 knees examined by magnetic resonance imaging in 16 patients subjected to a long-term corticosteroid therapy (6 systemic lupus erythematosus and 10 kidney transplanted people). Abnormal signals of condyles or tibial plateaus were observed in 12 patients (19 knees). Lesions, which were asymptomatic in 37% of the cases studied, mostly showed (12/24 condyles) a fatty signal area marked out by a hypointense signal strip in T1 edged with a hyperintense signal in T2. Some developed lesions were hypointense whichever the sequence. Our study confirmed the frequency of the lateral condyle involvement (60%) and the bilateral aspect of the lesions (50%) in osteonecrosis of the condyles following the corticosteroid therapy. The associated lesions of articular surfaces (3 cases) could be well assessed through magnetic resonance imaging on T2 or T2* weighted images. In two cases, the abnormal signals of the condyles suggesting a medullary edema (hypointense signal in T1 and hyperintense signal in T2) spontaneously disappeared 6 and 9 months after their discovery. Abnormal signals related to medullary infarcts (10 knees) were always associated with abnormal condyles. Most time their aspect in magnetic resonance imaging, except old calcified lesions, was characteristic: serpiginous hypointense signal isolating areas of fatty signal edged with a hyperintense signal strip in T2. In risk patients, magnetic resonance imaging allows early detecting knee necroses, precising the extent of epiphyseal and metaphyso-diaphyseal lesions and their impact on articular surfaces.

Adult↗
PubMed1991

Treatment of strabismus after retinal detachment surgery with botulinum neurotoxin A.

Thirty-one consecutive patients were treated with injections of Botulinum Neurotoxin A to rectus muscles for strabismus following retinal detachment surgery. In 14 cases the presenting problem was diplopia and in 17 cases the presenting problem was cosmetic appearance. A total of 67 injections was given. Twenty-seven cases had nine months or more follow-up. Of these, four of 11 cases with diplopia had fusion restored, four were shown to have no fusion potential, and three had temporary improvement only. In 16 cases with a primary cosmetic problem there was no useful effect in two, three had surgery as an alternative, three were realigned long-term, and eight had continuing maintenance therapy with toxin. Over half the series had undergone multiple detachment surgery, often for giant tears and other complex pathology.

Adult↗
PubMed1990

Behaviour of small children before induction. The effect of parental presence and EMLA and premedication with triclofos or a placebo.

The effect of the prescription of triclofos 70 mg/kg orally 90 minutes before operation on the behaviour of 263 children aged 1 to 5 years was studied in a blind, randomised, placebo-controlled trial. EMLA was applied to the dorsum of one hand when the premedication was administered, and all the children were accompanied by a parent during induction of anaesthesia. The frequency of satisfactory behaviour was significantly higher in the triclofos group (p less than 0.02), but the time spent in the recovery ward was increased.

Age Factors↗
PubMed1990

Effects of chewing behavior and ruminal digestion processes on voluntary intake of grass silages by lactating dairy cows.

Four primiparous Holstein-Friesian cows (518 kg average BW) with ruminal and duodenal cannulas were used to examine voluntary intake of direct cut (DC) or wilted (W) grass silage in relation to ruminal characteristics and chewing behavior. Dry matter content of the silages was 17.0 and 38.1%, concentrate DM intake was restricted to 5.0 and 5.3 kg/d, and voluntary DM intake from silages averaged 7.4 and 9.5 kg/d (P = .008), respectively. The acetate/propionate ratio in ruminal fluid decreased from 4.0 on DC to 3.3 on W silage (P = .021). The protein content in milk increased from 26.3 to 27.5 g/liter (P = .042) and the protein yield from 469 to 574 g/d (P = .038). The distribution of concentrates (38% of DM intake) with a mean particle size of .04 cm reduced differences in fecal mean particle size between diets. There was a shift from eating to ruminating on W silage with regard to daily duration (min/d) and number of jaw movements (no./d). However, ruminating index (no./kg DM intake) remained unchanged, irrespective of wilting and chop length of the silages or physiological state of the animals. These results are interpreted to indicate that the time lag for functional density of feed particles in the reticulorumen to increase, as affected by ruminating activity, not rate of reduction of the particle size, limits voluntary intake of grass silage by cattle.

Animals↗
PubMed1987

Hereditary amyloidosis: description of a new American kindred with late onset cardiomyopathy. Appalachian amyloid.

A family with hereditary amyloidosis characterized by peripheral neuropathy and cardiomyopathy is described. Lack of eye involvement sets their disease apart from the Indiana/Swiss familial amyloidotic polyneuropathy type II. The disease is of late onset; affected members die of cardiomyopathy after age 60. The late onset and lack of clinically significant neuropathy in several family members has led to misdiagnosis of the cardiomyopathy. Immunohistochemistry using antiprealbumin antiserum showed staining of amyloid deposits in nerve and heart.

Adult↗
PubMed1983

Skin antisepsis during steady-state hyperbaric exposure and subsequent decompression.

A custom-made container for the transfer of bacteriological sampling pads was used in a trial to test the feasibility of human skin disinfection during saturation or steady-state diving and subsequent decompression. Analysis of the results of colony counting and typing from 6 days of pre- and postcleansing samples taken during a recent saturation dive indicates that the skin of hyperbaric chamber occupants can be effectively sterilized in the event of a need to prepare for anesthetic or surgical procedures while still under pressure. A separate survey was also made to establish any pattern of change in bacterial flora of the chamber interior during the trial. Results of this survey are briefly discussed.

Antisepsis↗
PubMed1981

A pilot study of skin disinfection in the hyperbaric environment.

An opportunity was taken to carry out a pilot on human skin disinfection during a recent long-term saturation dive at extremely high pressure. Despite a number of difficulties, results were sufficiently encouraging to suggest that, given ideal conditions, sterilization of the skin in preparation for surgical or anesthetic procedures, or both, in a hyperbaric environment is possible.

Atmospheric Pressure↗
PubMed1976

Multifactor evaluations of surgical trainees and teaching services.

Surgical education has been exposed to increasing challenges as students have moved from the highly structured environment of a university hospital into a variety of clinical settings within the community. Presented with a general surgical service that uses ten relatively autonomous teaching services in seven hospitals, we have developed a computer-based evaluation system designed to provide quality control and a feed-back loop for trainee, teacher, and service. Trainees were rated by comparing them to their peers, with the chief resident as a reference standard. Profiles of each teaching service also were developed and compared one to the other. The results of both studies over a one year period are presented.

Educational Measurement↗