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Biomedical subjects

B Orden

Publications and source records attributed to B Orden.

30 records · Page 2Linked to original sources
PubMed1990

[Antimicrobial resistance of Haemophilus influenzae isolated outside of the hospital].

A total of 209 H. influenzae strains isolated from follow-up patients were studied. Twenty eight strains were serotype b (13.4%), 82 corresponded to type I of Kilian (39.2%), and 41 produced beta-lactamase (19.6%). Strains were resistant to trimethoprim-sulfamethoxazole (SXT) in 79.9% of cases, to the erythromycin in 18.2%, to tetracycline in 16.7%, to chloramphenicol in 13.8%, and to cefaclor in 0.1% of instances. There were no strains resistant to cefotaxime nor to amoxicillin/clavulanic acid. Resistances to three or more antibiotics were observed in 14.8% of the strains. The most common of these combinations was ampicillin-chloramphenicol-tetracycline SXT (61.3%).

Anti-Bacterial Agents↗
PubMedDate not supplied

Clonal differences among erythromycin-resistant Streptococcus pyogenes in Spain.

The aim of this study was to determine whether the high levels of erythromycin resistance in Streptococcus pyogenes found in Spain are due to the introduction and spread of one or more clones. Phenotypic and genotypic techniques were used to characterize all erythromycin-resistant S. pyogenes (ErR) isolated in Gipuzkoa, Spain, in the last 10 years and 128 ErR isolated in Vitoria and Madrid during 1996. Of 437 ErR, 97% had the M phenotype; all 283 of the strains studied had the mefA determinant of resistance. After biotyping, T serotyping, emm typing, and genotyping, four major clones were detected. Clones B (biotype I, type T4, emm4, pulsed-field gel electrophoresis [PFGE] II) and D (biotype V, type T8.25, emm75, PFGE IV) comprised 78.8% of all ErR. The resistance of S. pyogenes to erythromycin was mainly due to an efflux mechanism of resistance (M phenotype); few clones were responsible for it.

Anti-Bacterial Agents↗