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Biomedical subjects

B O Khatri

Publications and source records attributed to B O Khatri.

23 records · Page 2Linked to original sources

A technique for easy vascular access in patients undergoing plasmapheresis.

Gaining vascular access in some patients undergoing plasmapheresis procedure may prove to be difficult. Twenty-four percent of our patients had either a poor vascular access or poor blood flow. This report describes a technique for obtaining good vascular access in otherwise difficult patients, which we believe to be easy, safe, time saving and cost effective.

Catheterization↗

Plasmapheresis with acute inflammatory polyneuropathy.

Eleven children with acute inflammatory polyneuropathy were treated with a short course of intensive plasmapheresis. The 5 males and 6 females ranged in aged from 19 months to 16 years (mean: 7.8 years). The interval from disease onset to the initiation of plasmapheresis therapy was less than 7 days in 5 patients and less than 2 weeks in the others. At the time of the first plasmapheresis, 3 patients were on respirators (Grade 5 on the Guillain-Barré syndrome scale 0-6); 7 were bedridden (Grade 4); and 1 required assisted ambulation (Grade 3). One week after the last plasmapheresis, all but 1 patient had improved by 1 or more grades on the Guillain-Barré syndrome scale. At subsequent examination 6 months later, all patients were ambulatory and 9 of 11 had no significant neurologic findings. Electrophysiologic studies performed shortly before treatment initiation revealed predominant demyelinating neuropathy in 9 and axonal changes in 2. During the 76 plasmapheresis procedures, no severe complications were encountered. Although the number of patients treated is small, the clinical response observed would indicate plasmapheresis to be a safe and effective therapy in children with acute inflammatory polyneuropathy.

Adolescent↗