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Biomedical subjects

B Nielsen

Publications and source records attributed to B Nielsen.

At least 271 records · Page 15Linked to original sources

Malignant thyroid tumors at autopsy in a Swedish goitrous population.

In a series of 500 consecutive autopsies in a Swedish population with a high rate of goiter (29%) the incidence of malignant thyroid tumors was 6.0%. There were 25 papillary, 2 follicular, and 2 medullary carcinomas and 1 non-Hodgkin's lymphoma-immunocytoma. No significant differences in tumor incidence was found between goiter patients and those with normal glands. Notably the tumors occurred more often in men than in women (ratio, 1.5).

Adult↗

Investigation of TSH dependency, circulating thyroid autoantibody, and morphological features of recurrent nontoxic goitre.

Pathogenetical factors possibly responsible for recurrence of nontoxic goitre in a nonendemic area are evaluated. A group of 22 female patients admitted for surgical treatment of recurrent nontoxic goitre was compared with a control group of 86 female nontoxic goitrous patients not operated upon before. Preoperative serum baseline thyrotrophin levels in the recurrent goitre group were low normal and did not differ significantly from those in the control group. Circulating thyroid microsomal autoantibodies, thyroglobulin antibody titers, and the densities of lymphocytic aggregation in goitrous tissue did not differ significantly in the two groups. Thus, none of the parameters studied were likely explanations of regrowth of goitre.

Autoantibodies↗

Attempted suicide in Denmark. III. Assessment of repeated suicidal behaviour.

Ninety-nine patients, randomly chosen among hospital admitted suicide attempters, were initially interviewed at the Department of Psychiatry, Odense University Hospital, Denmark, and then followed up for a period of about 3 years. Half of the patients repeated the attempt in the follow-up period, mostly in the first year. Ten patients committed suicide, half of them in the first 3 months after the interview, shortly after discharge from hospital. The majority of the repeaters were living alone, while those that committed suicide were mostly married women aged 50-60 years. Other characteristic features for the repeaters were previous suicidal behaviour and suicidal behaviour among relatives. Many had a psychiatric record and expressed chronic somatic complaints. Around the time of the attempt, many expressed hopelessness, isolation and suicidal ideation. Pierce's Suicide Intent Scale performed poorly due, in particular, to low specificity. Future work will focus on objective risk factors, those indicated here and others, in order to establish an up-to-date background for assessment and management.

Adolescent↗