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Biomedical subjects

B Mozzanega

Publications and source records attributed to B Mozzanega.

29 records · Page 2Linked to original sources
PubMed1982

Post treatment behaviour of cervical intraepithelial neoplasia - grade III.

The behaviour in time of cervical intraepithelial neoplasia grade III has been evaluated in 141 patients treated for CIN III. It was observed that surgery ensures the higher healing-rate, whether hysterectomy or conization are performed, while diathermocoagulation seems unsatisfactory. Colposcopy, colpocytology and sight biopsies of the cervical canal, portio and vagina, which provide a precise lesion-map, are then essential investigations to make the subsequent treatment a truly radical one. A very close monitoring of patients, treated for CIN III, seems required in the first year after surgery, when we observed the highest rate of persistence and recurrences, while, subsequently, their incidence decreases as time passes by.

Biopsy↗
PubMed1981

GnRH--test in menopause. Its possible use in identifying the subjects at risk for dysplastic endometrial pathology.

The Authors, after reviewing the results of their previous studies on the endocrine situation in post-menopausal endometrial carcinoma and considering what emerges from the present work, suggest GnRh-Test as a mean to better identify the subjects at risk for this neoplasia; in patients already affected with endometrial cancer, it could be an indirect index in recommending or not endocrine therapy.

Aged↗
PubMed1981

Steroidogenesis in menopause and endometrial pathology.

After considering the postmenopausal variations in the hypothalamic-hypophyseal-ovarian feed-back system, the Authors review the medical literature about ovarian and adrenal contribution to postmenopausal steroidogenesis. Comparisons are made between postmenopausal sex-hormone levels in controls and in endometrial cancer affected patients; estradiol is given the main attention: its higher level in cancer patients seems closely related to their higher mean weight; indeed, no estradiol level difference is found between patients and controls correctly matched as to the body weight. The possible role of estradiol in the pathogenesis of endometrial cancer is then discussed basing on data obtained from women affected with diseases generally considered to be estrogen dependent.

Androgens↗
PubMed1981

Nephrotic syndrome in pregnancy: cortisone and prednisolone treatment: clinical case.

A case of a woman affected by a nephrotic postnephritic syndrome and treated during pregnancy with cortisone and prednisolone, is reported. The patient delivered at the 40th week of gestation a neonate with no malformations or clinical signs of adrenal deficiency. No interference between corticosteroid therapy and estrogen metabolism was noticed, and the intrauterine fetal growth, evaluated measuring the biparietal diameter, appeared normal.

Adult↗
PubMed1981

Inadequate luteal phase and benign breast disease.

The Authors compare E2 and Progesterone plasma levels in the luteal phase of twelve normally menstruating women whose basal body temperature curves were biphasic and in which breast micronodularity and mastodynia were present, with those of ten breast disease-free controls. The significant difference (p less than 0.001) found in Progesterone levels gives strength to the opinion that Progesterone supply therapy can effectively improve both mastodynia and the clinical picture objectively documented.

Adult↗
PubMed1980

Estrogen therapy in menopause and endometrial cancer.

The hormone dependency of endometrial cancer and the increase of its incidence seem to be generally accepted. The Authors expose the results of a four year retrospective epidemiological research aiming at verifying the possible role of menopausal estrogen assumption in the etiopathogenesis of the above mentioned disease. Two groups of post-menopausal patients were examined, who underwent total abdominal hysterectomy and bilateral salpingo-oophorectomy: 168 were endometrial cancer free, 50 were affected. The percentages of estrogen users, the exposition time and type of therapy were carefully analyzed in them. No correlation could be found between estrogen consumption, which resulted much lower than in the U.S.A., and endometrial cancer incidence. The relatively short assumption times, the different drug associations, and the hypoestrogenic origin of the most disturbing menopausal symptoms can help to explain this finding which is however, in agreement with what emerges from studies carried out in different countries by several Authors.

Estrogens↗
PubMedDate not supplied

[The Roux-en-Y jejunal loop in extrahepatic bilio-digestive anastomoses. Technic, indications and early complications in 101 cases].

Personal experience with Roux's Y loop in 101 cases in which bilio-jejunal anastomosis was performed for mechanical icterus of malignant (66 cases) and benign (35 cases) origin is described. It is felt that this operation does not present particular technical difficulties. End-to-end anastomosis is preferable. While bilio-duodenal and bilio-jejunal anastomoses are both sound practice, Roux's Y loop offers greater possibilities of application.

Adult↗