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Biomedical subjects

B Moyen

Publications and source records attributed to B Moyen.

At least 55 records · Page 3Linked to original sources
PubMed1984

Cartilage destruction in experimentally induced osteoarthritis.

Section of the anterior cruciate ligament in the knee joint of mature dogs resulted in a progressive fibrillation of both tibial and femoral condylar cartilages. Reduced tissue microhardness and increased water content preceded fibrillation while fixed charge density remained unchanged. A different histological pattern of initial fibrillation was found, however, in femoral and tibial cartilages which exhibited tangential cleft and vertical splits, respectively. Tangential fibrillation alone was associated with necrosis of superficial cells. This suggests that the mechanism of early osteoarthritic cartilage destruction varies in different articular surfaces.

Animals↗
PubMed1983

Hypertrophic repair of articular cartilage in experimental osteoarthrosis.

Section of the anterior cruciate ligament has been performed in the knee of 11 mature dogs. The macroscopically normal cartilage from patella and femoral trochlea of animals killed from 2 to 32 weeks after operation was used for histological, histomorphometrical, and biochemical analysis. Previously undescribed degenerative lesions of the superficial matrix were observed, and there was evidence for secondary healing of these lesions. An early and progressive decrease in superficial cell density and a later progressive increase in cartilage thickness without any change in the cell density of the middle and deep cartilage layers was found. A slight increase in water content with no reduction in glycosaminoglycan content was observed. The results suggest that joint laxity results initially in superficial degenerative changes and later in hypertrophic regenerative changes due to cell proliferation and increased matrix synthesis. Hypertrophic remodeling of articular cartilage in response to abnormal mechanical stresses is postulated.

Animals↗
PubMed1982

[Hemi-epiphyseal lengthening of the ulna in Kienboeck's disease].

The authors report the first results of a hemiepiphyseal lengthening of the ulna in a case of Kienböck's disease. Only the articular portion of the inferior epiphysis of the ulna is lengthened, the position of the styloid ulna being left untouched. The results of 17 cases are analysed. There were no cases of pseudarthrosis. The risk of conflict between the styloid ulna and the triquetrum is avoided.

Adolescent↗
PubMed1979

[The influence of direct electric current on bone formation (author's transl)].

The authors have studied the effects of a 20 microampere current applied to bone in rabbits and dogs. The results have been analysed according to the age of animal, whether mature or immature, and the nature of the electrode (whether steel or platinum). They found no different in the osteogenesis produced in the medullary canal which was constant. The authors further studied the effects of currents on osteotomies of the radius in dogs which generally led to non-union in the absence of electrical currents. They failed to demonstrate any stimulation of bone repair by the current. They conclude that bone formation in the medullary canal of intact bones and the repair of fractures are two different processes.

Age Factors↗