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Biomedical subjects

B Morag

Publications and source records attributed to B Morag.

88 records · Page 5Linked to original sources

Influenza immunization: serologic and clinical responses in military units.

Two inactivated influenza-virus vaccines were tested and compared in three army training units in Israel. The serological responses to the vaccines and the side-effects were assessed. The vaccines contained the influenza strains which were prevalent in 1974: A2/Port Chalmers/1/73 and B/Hong Kong/8/73. One of the vaccines also contained A2/England/42/72. Both vaccines caused a more than three-fold rise in geometric mean titers against influenza A strains, and about a twofold rise in geometric mean titers against influenza B/Hong Kong/5/73. Approximately 75%-80% of the vaccinees acquired protective hemagglutination-inhibition antibody titers against influenza A strains, while less than 30% acquired protective titers against B strains. In general, there were no significant differences between the serological responses to the two vaccines. More than 50% of the vaccinees experienced at least one systemic side-effect (50.3% with one vaccine and 61.0% with the other). The average number of side-effects per person was between 1.78 and 2.11. However, these side-effects were generally of short duration and caused minimal disability. On the whole, the two vaccines did not differ significantly with regard to the side-effects they caused.

Antibody Formation↗

The value of lymphangiography in chyluria: a report of three cases.

The lymphographic findings in three patients suffering from idiopathic chyluria are described. These findings included lymphangiectases and retrograde filling of kidney lymphatics;bilaterally in two and unilaterally in one patient. In the latter patient, the contrast was also seen entering the renal calyces and pelvis before passing to the bladder. The thoracic duct was patent in all three cases. The value of lymphangiography in patients with chyluria is emphasized.

Adult↗

A study of hepatitis B antigen carriers among schoolchildren in Netanya, Israel.

In the town of Netanya 9162 elementary schoolchildren (age 6-14 years) were tested for hepatitis B antigen (HBsAg) by the counter-electrophoresis method. The overall prevalence was 1.8% with a higher rate for males (2.2%) than for females (1.4%). Higher rates were observed among children born in the autumn and winter, particularly among the boys. This seasonal trend and male-female difference may partially be explained if infection occurs at circumcision. The ethnic distribution showed highest rates among children of Libyan and Yemenite origin (3.9% and 2.6%, respectively), and lowest rates among children of European and Israeli born parents (0.4% and 0.2%, respectively). Prevalence of HBsAg among children from large families and those from families living in poor and crowded quarters was very significantly higher than among children from smaller families living in richer areas and in less crowded conditions. These variables, which are closely associated with social class, remain significant after adjustment for ethnic origin and seem to account for a large proportion of the variation among the Israeli schoolchildren. The variation due to ethnicity is markedly reduced when adjusted for five other pertinent variables: age, sex, season of birth, crowding and family size. Assuming that prevalence of HBsAg in a population reflects the rates of infection (past or present), the results of this study strongly support the hypothesis that type B hepatitis in Israel behaves essentially as a contagious infection manifested primarily as a subclinical disease of early and mid-childhood.

Adolescent↗

Liposarcoma of the renal capsule in a 7 year old girl.

An unusual case is reported of a liposarcoma of the renal capsule in a 7 year old girl. Initial radiological studies revealed a fatty tumor related to the lower pole of the kidney. Selective renal angiography located the tumor to renal capsule and demonstrated its malignant nature.

Child↗

Detection of specific antigen-sensitized T-lymphocytes in human tonsils.

Tonsillar lymphocytes from children immunized against rubella were cultured with various mitogens, including phytohemagglutinin and rubella virus. Sheep red cells were subsequently added to detect rosette-forming T-lymphocytes, and the suspension tested by autoradiography to identify transformed cells. With PHA, 60--80% of the cells were transformed, of which 37% were rosette-forming T-cells. With rubella antigen only 31% of lymphocytes were transformed, but almost all of these formed rosettes. It is concluded that PHA stimulates B- as well as T-cells alone; such stimulation may therefore be a more reliable test of T-cell function and of cell-mediated immunity.

Animals↗

The value of tomography of the sterno-clavicular region.

Nine patients out of a series of 20 are presented illustrating some of the conditions which may affect the sterno-clavicular region (SCR). The value of tomography as a routine procedure in the study of the SCR is stressed, as in many cases the plain film studies fail to reveal clear-cut evidence of pathological changes. Establishing the exact aetiological nature of the lesion is not always possible by means of radiology alone. However, the radiological demonstration of disease in the SCR is invaluable as a guide to the further management of the patient.

Adolescent↗

In vitro correlates of cell-mediated immunity in human tonsils after natural or induced Rubella virus infection.

The techniques of hemagglutination inhibition and in vitro lymphocyte transformation and the assay of migration inhibitory factor were used for study of the development of rubella antibody activity in serum and tonsillar tissue washings and of the appearance of rubella-specific, cell-mediated immunity in circulating and tonsillar lymphocytes in groups of children who underwent tonsillectomy at various intervals after natural rubella infection, subcutaneous immunization with HPV-77 DE/5 vaccine, or intranasal inoculation with RA27/3 live, attenuated rubella virus vaccine. Antibody response in serum and tonsillar tissue washings was detected regularly after natural infection or immunization. Development of specific cell-mediated immunity in circulating lymphocytes was regularly observed after natural infection and frequently after immunization. Natural infection or intranasal immunization with rubella vaccine resulted in the appearance of cell-mediated immunity in the tonsillar lymphoid tissue, and the response was detectable up to several years after natural infection in several cases. It is significant, however, that the level of cell-mediated immunity in tonsils was conspicuously low after subcutaneous immunization. These data suggest the induction of local cell-mediated immunity in tonsillar lymphoid tissue after local mucosal application of rubella virus.

Adolescent↗

Percutaneous transluminal aortic angioplasty: early and late results.

Percutaneous transluminal angioplasty of the infrarenal abdominal aorta (13 patients) and its bifurcation (15 patients) was performed in 28 patients with a total of 32 dilatation procedures. The group consisted of 16 female and 12 male patients and initial successful dilatation was achieved in all. Recurrence within 1 month requiring bypass surgery occurred in 1 patient. Three patients were lost to follow-up. Long-term follow-up in the remaining 24 patients ranged from 1 to 9 years with a mean of 4.5 years. During the follow-up period, repeat angioplasty of the original stenosis was performed in 3 patients and another patient underwent dilatation of a new lesion which developed in the aorta. According to clinical and noninvasive studies, these 4 patients, as well as the other 20, have maintained patency of the treated lesions and are symptom free. No immediate complications requiring surgery occurred. We conclude that angioplasty is the initial treatment of choice in focal lesions of the distal abdominal aorta and its bifurcation.

Adult↗

Qualitative evaluation of antegrade percutaneous transluminal angioplasty by pressure waveform parameters.

When percutaneous transluminal angioplasty (PTA) is performed in an antegrade ("downstream") direction, intraluminal gradient measurements across the stenotic segment are not possible. Pressures recorded proximal to the lesion were evaluated for possible hemodynamic clues of changes in flow in ten consecutive patients before and after PTA. In all patients in whom the procedure was successful, the systolic pressure decreased by an average of 35 mm Hg. This decrease was not evident in the failed procedures. It is concluded that proximally recorded pressure changes can be used as an objective criterion to assess the success of PTA performed in arteries.

Aged↗

True sagittal CT scanning of the elbow.

OBJECTIVE: A new method to obtain true sagittal CT scans of the elbow joint is described. MATERIALS AND METHODS: The patient is placed prone on the CT table with the arm around and under the table. RESULTS: True sagittal images of the elbow joints and all the articulating surfaces were easily obtained in a standard and reproducible manner. CONCLUSION: For CT scanning of the elbow, true sagittal scanning is superior to axial views and is readily obtained by the described method.

Elbow↗

An unusual presentation of pancreatic carcinoma in childhood.

Carcinoma of the pancreas is rare in the pediatric population, with only 58 cases described in subjects under 16 years of age. The clinical presentation generally consists of abdominal pain and mass. We present a case of carcinoma of the pancreas in an 11-year-old girl, with abdominal pain and unusual behavior.

Abdomen↗

The "iliac vein compression syndrome" and lower limb vascular access for hemodialysis.

A chronic renal failure patient requiring an access vein for hemodialysis underwent an a-v shunting procedure in the left leg. Post operative proliferating edema of the limb warranted further investigation and iliac vein obstruction syndrome was discovered which existed occulty until venous insufficiency was precipitated by the construction of the a-v shunt. Ilio-caval by-pass graft was capable of correcting the high venous pressure and ensuring the patency of the a-v shunt. This occult syndrome appears to be present in a high precentage of autopsy findings and occurs predominantly on the left side in young females. It is proposed that this high risk groups undergo radionuclide venography before any vascular procedure is undertaken in order to ensure a patent iliac vein.

Adult↗